Metabolite_name RefMet_name 1020 1022 517 520 521 836 516 518 560 823 825 1030 1035 519 563 828 829 1019 1031 1032 1033 515 564 565 567 Factors - Sex:F | Genotype:DJ-1 Knockout Sex:F | Genotype:DJ-1 Knockout Sex:F | Genotype:DJ-1 Knockout Sex:F | Genotype:DJ-1 Knockout Sex:F | Genotype:DJ-1 Knockout Sex:F | Genotype:DJ-1 Knockout Sex:F | Genotype:WT Sex:F | Genotype:WT Sex:F | Genotype:WT Sex:F | Genotype:WT Sex:F | Genotype:WT Sex:M | Genotype:DJ-1 Knockout Sex:M | Genotype:DJ-1 Knockout Sex:M | Genotype:DJ-1 Knockout Sex:M | Genotype:DJ-1 Knockout Sex:M | Genotype:DJ-1 Knockout Sex:M | Genotype:DJ-1 Knockout Sex:M | Genotype:WT Sex:M | Genotype:WT Sex:M | Genotype:WT Sex:M | Genotype:WT Sex:M | Genotype:WT Sex:M | Genotype:WT Sex:M | Genotype:WT Sex:M | Genotype:WT 10-heptadecenoate (17:1n7) 10Z-Heptadecenoic acid 84055 76923 84055 142963 88527 106815 89942 119576 68738 84724 69332 111009 102461 115374 92405 114757 102063 76590 70914 97710 99167 91623 78743 104465 88993 10-nonadecenoate (19:1n9) Nonadeca-10Z-enoic acid 12188 16847 19710 18676 16069 15011 21492 16311 15423 17136 17266 16395 18789 23344 21806 20994 20731 17147 17591 17050 14403 11211 14333 8684 18854 15-HETE 15-HETE 141337 119880 126489 120967 136203 137262 129946 124358 128257 128867 119376 145558 134649 165704 120642 123431 101877 114059 125251 147729 107012 113511 149780 111747 118037 1-arachidonoylglycerophosphocholine (20:4n6)* LPC 20:4 23352 22121 28153 33333 33915 37834 39625 37718 26718 40918 26175 22385 22948 46150 40716 25916 31064 25269 19369 32252 33135 27224 41085 20365 29752 1-arachidonoylglycerophosphoethanolamine* LPE 20:4 119709 109265 126619 213261 185428 137678 162511 217422 119378 145848 143623 125864 127252 229432 120878 159182 165271 118370 154723 109349 119660 110511 138520 110721 142508 1-arachidonoylglycerophosphoinositol* LPI 20:4 169050 185703 251221 168322 135153 235420 142438 212307 100725 130087 150857 202677 203178 160245 176510 168322 95938 137047 106334 200208 219562 132765 142562 196812 125114 1-docosahexaenoylglycerol (1-monodocosahexaenoin) MG 22:6 12103 12940 21764 22170 17965 21887 21949 19283 16541 23221 14037 16481 22986 20024 24857 27498 23473 14806 16566 13820 20842 14994 22704 15777 18781 1-docosahexaenoylglycerophosphoethanolamine* LPE 22:6 324657 309519 314823 571254 492250 413883 418007 555709 389069 375048 371451 385564 378539 613308 351288 467126 523631 365106 470497 304994 347632 291352 490776 316080 459683 1-oleoylglycerophosphoethanolamine LPE 18:1 105213 110723 131398 203317 98223 152956 123818 150785 143553 115115 153468 156606 143110 183053 151657 124633 125459 116368 86230 154788 146046 145187 125666 143034 129674 1-oleoylglycerophosphoglycerol* LPG 18:1 55507 56692 65241 160625 141631 64486 60372 149481 73445 134705 64203 60482 75486 138417 53249 117287 189265 68438 56503 66595 43274 59149 144217 62470 70231 1-oleoylglycerophosphoinositol* LPI 18:1 45240 35763 57080 100833 48754 56682 42624 83226 38538 57239 51353 46984 51162 80065 55354 75987 42602 63265 28462 54841 48998 38255 58557 57527 43479 1-oleoylglycerophosphoserine LPS 18:1/0:0 46950 55399 46025 73704 60413 52095 58747 82898 51985 69700 57404 72314 51242 90322 38016 75019 95842 61884 50062 48071 47391 60118 81885 40446 54622 1-oleoylplasmenylethanolamine* LPE P-18:1 or LPE O-18:2 81816 84013 87062 162239 75306 92986 99808 138522 111081 102391 156150 143732 86898 160945 80151 114736 75041 117997 66121 164808 67577 172662 84244 156365 112852 1-palmitoylglycerophosphoethanolamine LPE 16:0 93455 93705 96999 152545 95732 139882 111407 131033 148254 87280 128911 143098 132111 165106 100938 108703 111427 103861 90132 109004 120376 101818 118713 102617 99707 1-palmitoylglycerophosphoglycerol* LPG 16:0 40785 38012 31345 104554 68310 33641 30583 93962 39773 79248 36000 50293 36004 69903 31430 65565 63657 44023 41835 37167 21886 36025 56616 35856 43045 1-palmitoylglycerophosphoinositol* LPI 16:0 56009 51009 82386 131965 59266 113841 60736 94253 46241 64922 68142 63965 84771 75701 79941 78672 51035 95880 43066 96476 89178 67900 65150 79171 62533 1-palmitoylplasmenylethanolamine* LPE P-16:0 or LPE O-16:1 78909 70637 81242 123008 74219 104066 78599 105267 87402 66319 124379 128706 85214 133213 92480 98519 84398 96038 60529 145030 85809 125785 67645 132858 86090 1-stearoylglycerophosphoethanolamine LPE 18:0/0:0 156131 181607 222717 299297 290930 207083 228524 264532 308599 230683 240101 256309 271382 325669 231827 235556 259998 237195 216006 211945 236071 230608 285348 219715 264181 1-stearoylglycerophosphoinositol LPI 18:0/0:0 143644 143671 149640 226607 191842 240078 171069 187326 146338 193322 120893 158288 225421 271201 178942 229105 202991 145567 142074 119786 225635 140113 267225 131697 181844 1-stearoylglycerophosphoserine* LPS 18:0 408779 445669 537029 603479 536053 651193 518682 522871 590048 477433 454179 626474 647497 648820 594000 574405 500654 509879 561077 533503 594767 515643 422271 518141 558926 1-stearoylplasmenylethanolamine* LPE P-18:0 or LPE O-18:1 41422 49651 115836 87488 54872 117339 88312 73150 37830 59480 117776 115829 133376 71866 119362 84213 5891 132673 59969 117823 107411 119812 11530 103312 95313 2-arachidonoylglycerophosphoethanolamine* LPE 20:4 82370 86405 68802 140801 139969 73793 114373 147526 101991 114958 99769 90162 86730 152178 74929 119982 192136 101675 125647 76012 73556 91581 175284 80244 105523 2-arachidonoylglycerophosphoinositol* LPI 20:4 26740 40691 32731 31706 23342 42040 22818 32976 14668 31090 27450 39871 34604 24285 32221 27801 17478 18748 13454 36112 32771 18531 25460 41507 22289 2-docosahexaenoylglycerophosphoethanolamine* LPE 22:6 188413 208676 159637 296457 361033 182391 252977 287487 233431 257088 206909 242146 224748 359068 201483 255600 452384 218689 278230 150963 175248 202664 390224 191552 246728 2-hydroxypalmitate 2-Hydroxypalmitic acid 40692 36097 24416 24611 36448 34123 26066 26041 35318 30543 37925 40144 31707 41561 26144 32604 42900 35476 32598 27522 24858 22766 30653 31940 35587 2-hydroxystearate 2-Hydroxystearic acid 22282 18337 14768 19996 21488 20399 17171 15602 21605 15857 22400 26088 21299 26850 14741 19042 22535 17425 22887 14734 19801 16680 12047 16202 19393 2-oleoylglycerophosphoethanolamine* LPE 18:1 85721 110316 97484 156010 76437 107390 89685 130198 131538 85007 139986 144196 113662 145504 111783 99681 105350 82890 107391 95507 120076 101291 116873 103814 78983 2-oleoylglycerophosphoglycerol* 51529 60412 40782 102757 62103 35591 35288 91972 41736 88129 47896 60595 37559 46134 30579 83187 76798 41406 43298 39347 31093 50048 54642 38546 45011 2-oleoylglycerophosphoserine* 24040 10842 16253 9832 12008 11438 18306 7527 16918 15926 38832 13079 18906 10978 15766 15772 15698 4546 11129 9142 28264 12274 9524 11052 2-palmitoylglycerophosphoethanolamine* LPE 16:0 14828 11636 12209 18638 17176 19090 15050 20846 16973 13435 19500 19270 18978 27434 19888 21102 10602 14385 21775 15159 15241 9820 15787 16001 12741 2-stearoylglycerophosphoinositol* LPI 18:0 6736 6928 8749 11019 12010 14485 7473 8164 7308 8365 8843 11466 8969 10655 12110 13910 10937 8478 7356 12766 6938 15746 9093 12399 3-(4-hydroxyphenyl)lactate Hydroxyphenyllactic acid 16784 15380 11297 17434 12124 16004 19503 19370 14334 21680 22481 16696 15315 16557 10087 17601 17072 17785 13733 18382 16392 14464 15495 14549 16801 3^-dephosphocoenzyme A 3'-Dephospho-CoA 3606 3770 3204 4152 3503 4445 3038 3504 2833 2783 3332 3933 2963 4756 3506 3783 3254 3220 3156 2741 2977 3640 3043 3856 3240 3-indoxyl sulfate Indoxyl sulfate 8528 7036 11266 17377 5806 6401 10675 4401 16896 13481 9467 6913 5217 13622 5044 11848 8227 6809 8905 8588 3383 4897 7978 3739 3175 5-HETE 5-HETE 53487 49384 71852 55692 58065 71105 49038 39663 44473 55005 62414 61955 66177 58412 49509 43803 37453 44211 45634 73735 62611 52467 53936 45906 44534 5-oxoproline Pyroglutamic acid 172144 188907 191306 187180 185875 170411 176499 174506 203839 187437 203439 185321 177285 185262 187230 156240 182776 180037 177239 181267 150520 159914 168075 170405 170127 acetyl CoA Acetyl-CoA 3809 7183 4729 1477 3394 1573 2819 2010 2329 2987 3485 2762 2422 1495 2512 3496 3029 2755 2160 2718 2060 3082 2518 2953 adenosine 5^diphosphoribose ADP-ribose 343243 293724 409322 366118 353982 294636 345951 380008 326079 358287 258130 234944 253202 241188 306845 369525 224861 331675 339961 414117 422343 312756 300487 358455 324947 adenylosuccinate Adenylsuccinic acid 10772 12185 15562 11837 10122 7969 15835 10568 13179 12383 9511 11151 12278 7136 8073 8480 8747 11927 11866 16810 23622 10494 9090 10385 8783 adrenate (22:4n6) Adrenic acid 778923 674460 914936 1302202 1068646 882351 421825 977201 572916 442506 602252 468218 409307 1001282 582975 836600 1484419 955665 437322 1411519 1320798 512625 646754 276622 1089799 anserine Anserine 7336 7385 10109 9688 9286 12076 9534 8785 10060 9842 11025 12564 11525 14301 13010 10697 12161 10483 10902 10440 10956 11797 10566 12228 11243 arachidonate (20:4n6) Arachidonic acid 9938313 9923048 10842240 10636192 9087156 10416557 8764126 10600578 7511767 9163036 8246658 9945511 10306034 9888742 8918530 9089146 8039653 8662074 7559046 10195487 9421222 9221103 8381212 9809715 8519348 beta-muricholate beta-Muricholic acid 7183 3612 carnosine Carnosine 86499 90228 96377 93738 106953 110131 96282 84164 98017 105814 118470 104738 110574 108927 106789 100130 100622 101145 106307 113262 100381 117886 101380 105700 97018 coenzyme A Coenzyme A 5992 6006 5637 5279 6041 5480 5749 5761 5128 5701 6092 5441 5642 6524 6292 5835 5673 6301 5662 5384 4496 6669 5179 5254 6161 dihomo-linoleate (20:2n6) 11Z,14Z-Eicosadienoic acid 48098 50671 59179 72534 66979 82306 59595 65787 50522 63866 57129 65989 67101 84370 65040 77984 66870 58520 54444 61509 68059 54856 71363 60507 65363 dihomo-linolenate (20:3n3 or n6) Dihomo-gamma-linolenic acid 206659 194092 177547 266283 232461 259778 191695 303529 171183 264020 190141 240728 240420 315132 209263 306201 224045 263830 210838 250321 235995 223915 291299 222530 261425 dihydroxyacetone phosphate (DHAP) Dihydroxyacetone phosphate 42570 34210 41532 34979 41919 32365 43274 43372 55268 50535 50247 37981 38072 35391 37973 32443 40045 53203 66673 56854 57656 50961 40992 52433 58229 docosahexaenoate (DHA; 22:6n3) LPC 22:6 1940103 2031953 1869977 1978670 1648536 2102671 1455775 1928443 1257859 1653713 1550830 2115043 1988409 1984736 1849565 1879068 1472838 1605074 1422953 1903763 1784944 1775439 1701922 1929881 1624914 docosapentaenoate (n3 DPA; 22:5n3) DPA 89524 82100 115611 131899 86584 116169 67624 128615 50661 110545 67930 97489 104764 126825 99163 139041 112238 78355 73496 122174 98742 97301 126175 94459 86516 docosapentaenoate (n6 DPA; 22:5n6) Docosapentaenoic acid (22n-6) 20624 24073 34007 19442 23447 29184 31351 14027 30862 16506 12762 22750 18243 19340 23604 42279 22407 16705 21546 12864 22441 13975 18799 eicosapentaenoate (EPA; 20:5n3) Eicosapentaenoic acid 143778 136855 154025 143881 102635 229583 106475 138284 100698 123652 91930 208101 248266 195868 229764 152037 117677 177426 157209 235769 286959 203606 167592 259782 172998 eicosenoate (20:1n9 or 11) cis-Gondoic acid 156764 132862 167949 236444 194477 195170 191470 197444 168808 205123 166177 174394 191226 235208 170981 182078 157640 156649 173693 157278 165540 153528 182431 164278 213582 flavin adenine dinucleotide (FAD) FAD 19491 17144 16816 18226 17305 17188 17260 18172 17884 16514 17502 19723 18776 15484 17752 17148 18372 17178 18442 17352 18408 18073 16837 16989 17100 guanosine 5^-diphospho-fucose 9793 8526 8799 8953 8155 7552 7447 7222 8563 7517 7922 9560 8176 8004 6911 6755 7700 7751 7263 8049 7170 7273 5294 6784 6974 histidine Histidine 46275 52472 60408 53697 51216 58025 58582 57415 69815 55926 62274 46930 47560 54958 38992 47212 46632 51504 53032 54105 55311 61093 45377 49560 55947 homocarnosine Homocarnosine 83531 60005 105551 113921 109126 122063 104493 117398 123079 119160 126426 118777 106232 114743 132411 105150 116187 117995 124046 132766 113184 141949 124269 117493 128394 hypoxanthine Hypoxanthine 98999 96545 91401 107907 98292 93008 92548 98407 94744 105832 115579 106721 92350 108332 92106 90170 96231 98878 90472 94001 85279 93033 101148 89432 93281 inosine Inosine 975502 836983 1170832 1107014 1020000 1023247 985832 1019687 1002496 1041386 1035010 1030893 917125 1001682 1007712 968260 837574 977903 952839 1022930 886257 941758 896026 925820 1017270 Isobar: fructose 1_6-diphosphate_ glucose 1_6-diphosphate_ myo-inositol 1_4 or 1_3-diphosphate 9523 10043 14860 9860 12349 8683 17707 13589 18635 11399 10605 11662 12148 9157 12297 9232 13074 14428 19784 21747 14042 12238 7757 17104 15458 linoleate (18:2n6) Linoleic acid 280178 321797 311790 336780 303123 380396 263458 346115 241914 303856 306173 412362 367154 520925 309391 433322 301192 346500 284510 332370 370136 367491 409852 391783 378828 linolenate [alpha or gamma; (18:3n3 or 6)] Octadecatrienoic acid 20954 23598 25455 24094 15876 35491 18716 19391 12739 17796 20310 33587 37337 50491 32392 30050 18130 22511 20320 33600 37263 32680 32874 50515 31327 margarate (17:0) Margaric acid 157666 140288 160848 192360 166437 198721 165942 183117 162856 162325 158212 174502 181833 204203 166747 215297 197534 156183 159631 177940 196886 151604 175923 156441 164946 mead acid (20:3n9) ETrE(5Z,8Z,11Z) 67672 52148 65390 111526 80093 108919 71793 100026 50103 113391 61146 72490 94394 137380 95272 93072 108787 80678 86147 66768 112711 87204 107006 93649 81258 myo-inositol hexakisphosphate Myo-inositol hexakisphosphate 5492 4866 4107 3560 4456 3617 3747 5314 4689 5372 5701 4642 5157 3666 3903 4174 4314 4790 4702 4428 4847 4580 4503 3500 N-acetylmethionine N-Acetylmethionine 23175 22429 19109 16775 20430 17599 20547 19375 23584 23651 24548 21165 20392 18135 20093 19620 22451 25656 24307 22733 21692 24297 24107 23326 23123 N-oleoyltaurine N-Oleoyl taurine 10477 17507 14056 33577 28873 15201 12876 43170 15615 27893 12408 15793 13934 31721 16785 31320 26422 17298 15512 19392 11915 20093 30778 20502 14709 N-palmitoyltaurine N-Palmitoyl taurine 32481 38396 31632 55984 33248 31047 21825 63136 22282 37474 21956 42989 27892 42327 26444 49053 37220 28135 21232 42814 28474 35579 35168 34428 25300 N-stearoyltaurine N-Stearoyl taurine 10737 14544 15171 11359 18091 22565 21823 15254 15300 12561 19229 15623 20804 18506 18334 18980 18467 23249 18271 14485 17351 15086 11498 21420 18211 oleic ethanolamide Oleoyl-EA 39846 35680 32671 52144 40754 49809 34154 46394 30454 40917 34764 37415 37962 42161 44259 38462 37458 37927 40987 36135 40503 37072 41316 41003 39084 palmitate (16:0) Palmitic acid 4592306 4100574 4804692 5180387 4998078 5054257 4448735 5221741 3977673 5206167 4796638 4520128 4827028 5822000 4401366 5133034 4360099 4748611 4213022 4734620 4881287 4229426 4572834 4433346 5062332 palmitoleate (16:1n7) Palmitoleic acid 324209 346085 293267 311034 265825 352154 240204 304551 216585 271758 280123 327307 412337 415602 350079 321258 285041 262529 295241 313183 393611 335610 313897 412284 298628 palmitoyl ethanolamide Palmitoyl-EA 37618 34466 30470 51838 43138 45212 38126 44526 36206 45829 34446 36407 41528 46456 35519 36433 36585 34291 35467 29797 32555 36762 37374 32800 44600 phenol sulfate Phenyl hydrogen sulfate 4110 2254 6751 9739 4059 8117 5614 3267 6874 5587 5610 4271 8261 12501 9530 9719 5598 6847 4226 4866 5620 8032 7604 6345 4796 phosphoethanolamine Phosphoethanolamine 68637 70984 73777 69523 68998 64706 79188 68557 69363 70284 70016 69583 67848 67265 64140 67213 65949 65994 71209 68022 70854 65288 67804 67200 74195 prostaglandin D2 PGD2 18570 14976 18441 14770 20981 18979 16272 11908 19322 14925 16656 25552 20853 16971 19898 13221 22690 19618 19320 25719 12398 16431 18781 15185 16069 prostaglandin E2 PGE2 13601 10890 10808 9751 12289 13000 8976 11080 13833 10703 10846 14651 13443 11381 11020 9358 13177 10769 11096 15669 11307 11460 10844 12770 11472 pseudouridine Pseudouridine 13310 12938 11087 8743 11405 12125 11483 11087 11196 11157 12722 12358 12045 10338 13185 9747 12101 11929 11022 12068 12017 10933 12028 12116 9769 S-adenosylhomocysteine (SAH) S-Adenosylhomocysteine 14917 16541 13119 16166 17625 17412 13594 15550 14906 15889 17042 16738 16062 20094 13813 15932 14766 14833 13137 12625 13581 13992 16780 12504 14795 stearate (18:0) Stearic acid 6903942 6783872 7672407 8323678 7953813 7892882 8043163 7901751 7424240 8108426 6880371 6865979 8188607 8853952 6986947 7824647 7292646 6866534 7574026 7131261 8015681 6573987 7356924 6645269 7996089 succinate Succinic acid 12736 9694 8017 15382 11436 14131 11173 14752 12077 11015 10501 12801 12061 14888 9663 13273 10568 11822 11522 12030 12886 10997 13679 10251 12294 sucrose Sucrose 29828 246698 5953 33454 9495 16191 58147 13055 17851 5989 10818 6875 98693 10586 tauro(alpha + beta)muricholate Tauromuricholic acid 5339 53871 taurocholate Taurocholic acid 3459 2685 2987 3686 7373 2503 3285 3698 107966 uridine Uridine 292626 279900 248337 246933 263833 263631 263513 235369 268785 259897 280249 268057 256257 241229 262914 256888 254906 284541 247569 272864 267255 246901 283003 266810 268400