#METABOLOMICS WORKBENCH huntermoseley_20180413 DATATRACK_ID:1370 STUDY_ID:ST000949 ANALYSIS_ID:AN001558 PROJECT_ID:PR000653 VERSION 1 CREATED_ON April 18, 2018, 3:21 pm #PROJECT PR:PROJECT_TITLE NK versus CD8 T naïve and CD8 T memory PR:PROJECT_SUMMARY Exp to look at lactate/ alanine excreted in supernatant, lactate, citrulline and PR:PROJECT_SUMMARY other TCA intermediates inside cells PR:INSTITUTE University of Kentucky PR:DEPARTMENT Markey Cancer Center PR:LAST_NAME Lutz PR:FIRST_NAME Charlie PR:ADDRESS Dept Of Pathology, UKMC PR:EMAIL ctlutz2@uky.edu PR:PHONE 000-000-0000 #STUDY ST:STUDY_TITLE Human NK vs T cell metabolism using 13C-Glucose tracer (part I) ST:STUDY_TYPE isotope tracer ST:STUDY_SUMMARY NK versus CD8 T naïve and CD8 T memory SIRM experiment using 13C-Glucose tracer ST:INSTITUTE University of Kentucky ST:DEPARTMENT Markey Cancer Center ST:LAST_NAME Presnell ST:FIRST_NAME Steve ST:ADDRESS Dept Of Pathology, UKMC ST:EMAIL srpres2@uky.edu ST:PHONE 000-000-0000 ST:STUDY_COMMENTS For additional comments about the study, like listing a publication. #SUBJECT SU:SUBJECT_TYPE Animal SU:SUBJECT_SPECIES Homo sapiens SU:TAXONOMY_ID 9606 #SUBJECT_SAMPLE_FACTORS: SUBJECT(optional)[tab]SAMPLE[tab]FACTORS(NAME:VALUE pairs separated by |)[tab]Additional sample data SUBJECT_SAMPLE_FACTORS - 20150505_NK_plate1-cells cell_type:NK protocol.id=12CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_NK; cell_count=1000000; cell_type=NK; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_NK_plate1; cell_type=NK; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=12CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_NK_plate1-cells; cell_type=NK; protocol.id=cell_quench_collection; lineage_6=Donor_SRP_blood_20150505_NK_plate1-cells-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=-1; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_NK_plate1-sup cell_type:NK protocol.id=12CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_NK; cell_count=1000000; cell_type=NK; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_NK_plate1; cell_type=NK; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=12CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_NK_plate1-sup; cell_type=NK; protocol.id=cells_media; lineage_6=Donor_SRP_blood_20150505_NK_plate1-sup-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=0.388; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_NK_plate2-cells cell_type:NK protocol.id=13CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_NK; cell_count=1000000; cell_type=NK; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_NK_plate2; cell_type=NK; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=13CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_NK_plate2-cells; cell_type=NK; protocol.id=cell_quench_collection; lineage_6=Donor_SRP_blood_20150505_NK_plate2-cells-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=-1; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_NK_plate2-sup cell_type:NK protocol.id=13CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_NK; cell_count=1000000; cell_type=NK; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_NK_plate2; cell_type=NK; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=13CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_NK_plate2-sup; cell_type=NK; protocol.id=cells_media; lineage_6=Donor_SRP_blood_20150505_NK_plate2-sup-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=0.402; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_memory_plate5-cells cell_type:CD8_T_memory protocol.id=12CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_memory; cell_count=870000; cell_type=CD8_T_memory; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_memory_plate5; cell_type=CD8_T_memory; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=12CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_memory_plate5-cells; cell_type=CD8_T_memory; protocol.id=cell_quench_collection; lineage_6=Donor_SRP_blood_20150505_T_memory_plate5-cells-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=-1; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_memory_plate5-sup cell_type:CD8_T_memory protocol.id=12CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_memory; cell_count=870000; cell_type=CD8_T_memory; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_memory_plate5; cell_type=CD8_T_memory; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=12CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_memory_plate5-sup; cell_type=CD8_T_memory; protocol.id=cells_media; lineage_6=Donor_SRP_blood_20150505_T_memory_plate5-sup-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=0.332; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_memory_plate6-cells cell_type:CD8_T_memory protocol.id=13CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_memory; cell_count=870000; cell_type=CD8_T_memory; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_memory_plate6; cell_type=CD8_T_memory; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=13CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_memory_plate6-cells; cell_type=CD8_T_memory; protocol.id=cell_quench_collection; lineage_6=Donor_SRP_blood_20150505_T_memory_plate6-cells-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=-1; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_memory_plate6-sup cell_type:CD8_T_memory protocol.id=13CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_memory; cell_count=870000; cell_type=CD8_T_memory; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_memory_plate6; cell_type=CD8_T_memory; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=13CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_memory_plate6-sup; cell_type=CD8_T_memory; protocol.id=cells_media; lineage_6=Donor_SRP_blood_20150505_T_memory_plate6-sup-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=0.344; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_naive_plate3-cells cell_type:CD8_T_naive protocol.id=12CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_naive; cell_count=650000; cell_type=CD8_T_naive; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_naive_plate3; cell_type=CD8_T_naive; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=12CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_naive_plate3-cells; cell_type=CD8_T_naive; protocol.id=cell_quench_collection; lineage_6=Donor_SRP_blood_20150505_T_naive_plate3-cells-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=-1; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_naive_plate3-sup cell_type:CD8_T_naive protocol.id=12CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_naive; cell_count=650000; cell_type=CD8_T_naive; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_naive_plate3; cell_type=CD8_T_naive; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=12CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_naive_plate3-sup; cell_type=CD8_T_naive; protocol.id=cells_media; lineage_6=Donor_SRP_blood_20150505_T_naive_plate3-sup-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=0.251; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_naive_plate4-cells cell_type:CD8_T_naive protocol.id=13CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_naive; cell_count=650000; cell_type=CD8_T_naive; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_naive_plate4; cell_type=CD8_T_naive; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=13CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_naive_plate4-cells; cell_type=CD8_T_naive; protocol.id=cell_quench_collection; lineage_6=Donor_SRP_blood_20150505_T_naive_plate4-cells-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=-1; weight%units=g SUBJECT_SAMPLE_FACTORS - 20150505_T_naive_plate4-sup cell_type:CD8_T_naive protocol.id=13CGlc; lineage_1=Donor_SRP; protocol.id=normal; species=Homo sapiens; species_type=Animal; taxonomy_id=9606; lineage_2=Donor_SRP_blood_20150505; protocol.id=blood_collection; lineage_3=Donor_SRP_blood_20150505_T_naive; cell_count=650000; cell_type=CD8_T_naive; protocol.id=cell_extraction; lineage_4=Donor_SRP_blood_20150505_T_naive_plate4; cell_type=CD8_T_naive; plate_media_tare=-1; plate_media_tare%units=g; protocol.id=13CGlc; replicate=1; replicate%type=biological; lineage_5=Donor_SRP_blood_20150505_T_naive_plate4-sup; cell_type=CD8_T_naive; protocol.id=cells_media; lineage_6=Donor_SRP_blood_20150505_T_naive_plate4-sup-polar_GCMS_A; protocol.id=polar_extraction; replicate=1; replicate%type=analytical; type=polar; weight=0.251; weight%units=g #COLLECTION CO:COLLECTION_SUMMARY Blood collected from a draw. Collection and quench of cells in tissue culture CO:COLLECTION_SUMMARY Media is extracted from plate. CO:COLLECTION_PROTOCOL_ID blood_collection cell_quench_collection cells_media CO:COLLECTION_PROTOCOL_FILENAME WS_Fan_Quench_cell_tissue.pdf CO:SAMPLE_TYPE T-Cells #TREATMENT TR:TREATMENT_SUMMARY Grown in unlabeled glucose. Grown in labeled glucose. Normal human, no TR:TREATMENT_SUMMARY treatment. TR:TREATMENT_PROTOCOL_ID 12CGlc 13CGlc normal #SAMPLEPREP SP:SAMPLEPREP_SUMMARY Cells of interest extracted from the blood. Polar extraction from cells. SP:SAMPLEPREP_PROTOCOL_ID cell_extraction polar_extraction SP:SAMPLEPREP_PROTOCOL_FILENAME WS_Fan_Extract_Polar_Lipid_Prot.pdf #CHROMATOGRAPHY CH:CHROMATOGRAPHY_SUMMARY Targeted GC CH:CHROMATOGRAPHY_TYPE GC CH:INSTRUMENT_NAME GC-EI-MS, Thermo ITQ CH:COLUMN_NAME SGE 0.15 mm i.d. x 50 m fused silica open-tubular column, coated with 0.25 µm BPX-5 (5% phenylmethyl- phenylsiloxane) CH:COLUMN_NAME BPX-5 (5% phenylmethyl- phenylsiloxane) #ANALYSIS AN:ANALYSIS_TYPE MS #MS MS:INSTRUMENT_NAME Thermo ITQ MS:INSTRUMENT_TYPE GC-ITQ MS:MS_TYPE EI MS:ION_MODE POSITIVE MS:MS_COMMENTS GCMS Analytical Experiment with detection of compounds by comparison to MS:MS_COMMENTS standards. Derivitization is done with MTBSTFA MS:MS_COMMENTS (N-methyl-N-[tert-butyldimethylsilyl]trifluoroacetamide). #MS_METABOLITE_DATA MS_METABOLITE_DATA:UNITS normalized peak area MS_METABOLITE_DATA_START Samples 20150505_NK_plate1-cells 20150505_NK_plate1-sup 20150505_NK_plate2-cells 20150505_NK_plate2-sup 20150505_T_memory_plate5-cells 20150505_T_memory_plate5-sup 20150505_T_memory_plate6-cells 20150505_T_memory_plate6-sup 20150505_T_naive_plate3-cells 20150505_T_naive_plate3-sup 20150505_T_naive_plate4-cells 20150505_T_naive_plate4-sup Factors cell_type:NK cell_type:NK cell_type:NK cell_type:NK cell_type:CD8_T_memory cell_type:CD8_T_memory cell_type:CD8_T_memory cell_type:CD8_T_memory cell_type:CD8_T_naive cell_type:CD8_T_naive cell_type:CD8_T_naive cell_type:CD8_T_naive Ala-13C00 0.012284264193835768 0.011357772644171411 0.00715457148422022 0.008863047578767227 0.020250687929927652 0.0062016872499461185 0.028544334131178004 0.00871871029463772 0.013923258515975898 0.0071108127236165315 0.018323625557476783 0.006236527911378493 Ala-13C01 0 0.0005190143133911073 0.0014646981218073812 0.0005556775851206985 0.0017398421642245063 0.0002997794733611611 0.0008904699452066238 0.0005869563470051606 0.0023875463195147874 0.00027657525331793964 0.0011230266409308126 0.00030808633944799045 Ala-13C02 0.0007999375311290242 0.0001380557354167461 8.355706546861143e-05 0.0017118903485191573 0.0002431549777109676 0 0.0005039218599162431 0.0006655633929056354 0 7.879969412655191e-05 0 0.0004331115103464117 Ala-13C03 0.0020645963441702432 6.154372296573176e-05 0.001152853967888571 0.0010116708921476681 0.001031607749584068 0.00016119257747997811 0.0026380354669780625 0.0010191980781223476 0.0028663375542331416 0.0001192932648233296 0.003458839848826038 0.0003766157993642218 Ala-ALL 0.015148798069135036 0.012076386415944997 0.009855680639384783 0.012142286404554751 0.023265292821447195 0.0066626593007872575 0.032576761403278934 0.010990428112670864 0.019177142389723827 0.007585480935884353 0.022905492047233633 0.007354341560537117 Arg-13C00 0.011281543980186031 3.8183004123566233 0.009172579167054011 3.9681423733199046 0.02455638572936718 2.358147143801019 0.14886024846408152 3.521148547786606 0.02094657711991525 2.6373533049521463 0.02067227422005658 2.2793083403724066 Arg-13C01 0 0.30401031262445843 0 0.3421608450996715 0 0.19463554806982256 0.014844992180863542 0.30117290172558564 0 0.1645322241775054 0.01211582753993523 0.16026923472307528 Arg-13C02 0 0.022602253979498665 0.00925257650468811 0 0.005127394867555738 0.022447924296180827 0.011864563073675834 0 0.012141534420453988 0 0 0.04168268352376768 Arg-13C03 0.011140861658178283 0.020944577584329483 0 0.028597523627391805 0 0.009190081706036768 0.006898086877128624 0 0.016984046403796804 0.0014844921217491108 0 0 Arg-13C04 0 0 0 0.005322419971061476 0 0.0002730675614036768 0 0.002291538659152073 0 0.0068419816704028925 0 0 Arg-13C05 0 0 0.00768432903188518 0 0 0.002113006969909568 0 0 0 0.004602875896060723 0 0.0013714324084731046 Arg-13C06 0 0.0006961849753573041 0 0 0 0 0 0.0017150359564640928 0 0 0 0 Arg-ALL 0.022422405638364312 4.166553741520268 0.026109484703627298 4.344223162018029 0.02968378059692292 2.5868067724043726 0.18246789059574953 3.8263280241278075 0.05007215794416604 2.8148148788178644 0.03278810175999181 2.4826316910277226 Asn-13C00 0.023755382701566522 0.9589858630433256 0.01560768434768552 1.2531653865489547 0.02693457741370465 1.0496697366939602 0.06307633389590452 1.5249404786414031 0.024261897228198433 1.2506513922061437 0.0109907065231079 1.0432880184013897 Asn-13C01 0.0011203319798527645 0.04084427466065601 0.002896456919224517 0.04580296320645103 0.00043388578849341017 0.03205310686882838 0.004093861912428697 0.06818358813519179 0 0.054303255229162135 0 0.06592093366773208 Asn-13C02 0 0 0 0.009980284786080026 0 0.008845085285886317 0 0.012452215189233071 0.0026970667116128955 0.0003031365873464196 0 0.020347094129616834 Asn-13C03 0.001482599038795513 9.467838305307876e-05 0 0.003618847001243517 0.002233619193012537 0 0 0 0 0.004015631796935685 0 0 Asn-13C04 0 0.00015095034212808957 0 0 0 0.0012445164696040752 0 0.0005801576708389052 0 0.0024182837998230765 0 0.005492427604844437 Asn-ALL 0.0263583137202148 1.0000757664291628 0.018504141266910037 1.312567481542729 0.0296020823952106 1.091812445318279 0.06717019580833321 1.6061564396366668 0.02695896393981133 1.3116916996194112 0.0109907065231079 1.135048473803583 Asp-13C00 0.33260923826307615 0.335428399358301 0.1651181711880442 0.28890486787549435 0.2920958595591355 0.2305144409122878 0.22274438150602102 0.27805316213424675 0.4233390007913347 0.2253651271929393 0.2522794059614461 0.21936221235991496 Asp-13C01 0.00903277451522116 0.0073315632544229984 0.02818533725736134 0.010187902984119087 0.006378896366321453 0.001557143272795226 0.03816209358785773 0.020352681889642853 0.012666554093697735 0.008183524195071944 0.04633363866144143 0.006654870810452371 Asp-13C02 0 0.0030142546021544787 0.013866736311653713 0.005888522935325967 0.0030676448302868124 0.004482575495088273 0.025846320115347068 0 0.015292448246478374 0.0003543513753927129 0.03192031833249461 0.002038791024573329 Asp-13C03 0.0009339205645570826 0.0011322506498672982 0.005458060435559856 0.0015254999371794226 0.0009990436433550299 0.001941834164929237 0.0036871957112774127 0.001018650837402605 0 0 0.0018745937731477979 0.0018826375016686315 Asp-13C04 0.0020044930878881707 0 0 0 0 0 0.0010832052323997785 0 0 0.0013575290075601692 0.0015650912975905926 0 Asp-ALL 0.3445804264307426 0.34690646786474577 0.2126283051926191 0.30650679373211887 0.30254144439909875 0.2384959938451005 0.291523196152903 0.2994244948612922 0.45129800313151075 0.23526053177096415 0.3339730480261205 0.2299385116966093 Cys-13C00 0 Cys-13C01 0 Cys-13C02 0 Cys-13C03 0 Cys-ALL 0 GAB-13C00 0.005507274709896462 0.0008930311672719026 0 0.0006288589824090538 0 0.00024525124403834453 0 0.00044449661637966563 0 0.0008191424839307891 0.004273362289296595 0 GAB-13C01 0 0.0001638916627353119 0 0 0 0.00014830712559984482 0 0.00027205569295653823 0 0.00030438002880050146 0 0 GAB-13C02 0 0 0 0.0004348796555536378 0 8.747782134084697e-05 0 9.036308369031973e-05 0 5.162381911164705e-05 0 0 GAB-13C03 0 0.0001974765647892898 0 0 0 0.0001683157855176673 0 0.0003043299538185665 0 0.0009916082142025387 0 0 GAB-13C04 0 0 0 0 0 0.00025296478557509954 0 0.00018987494361732502 0 0 0 0 GAB-ALL 0.005507274709896462 0.0012543993947965043 0 0.0010637386379626916 0 0.0009023167620718032 0 0.001301120290462415 0 0.002166754546045476 0.004273362289296595 0 Gln-13C00 0.010844208205604746 6.156708627167193 0.011873596432867591 6.351978873093119 0.015429647829265144 5.045591203938958 0.16874724308956457 7.371279402653941 0.009231174685189678 5.697544967408429 0.004570972050318513 4.818173916446785 Gln-13C01 0.004642776718235078 0.2238693590141917 0 0.31089346228790876 0.0004514602408128222 0.34317086708475497 0.0072014461414844555 0.42203318232800796 0 0.37766395523967394 0.0029619824196029433 0.34835409339042783 Gln-13C02 0 0.08870331170804546 0.0018943464297831235 0.019016131489679993 0 0.018298993048338413 0.00421367237441 0.040737778041557426 0 0.03473155531263633 0 0.0035164812006198416 Gln-13C03 0 0.01440553473257058 0 0.012936217337838816 0 0.00017510607739561283 0.001179360002078096 0.007471874456463232 0 0 0 0 Gln-13C04 0 0 0 0 0 0.002437446631697015 0.0006362559870902157 0.02233199568199579 0 0.009466605221707235 0 0.009999350739825738 Gln-13C05 0 0 0 0.005004318732262236 0 0 0 0 0 0 0 0 Gln-ALL 0.015486984923839823 6.483686832622 0.013767942862650715 6.699829002940809 0.015881108070077966 5.409673616781144 0.18197797759462736 7.863854233161965 0.009231174685189678 6.1194070831824465 0.007532954469921456 5.180043841777659 Glu-13C00 0.4812325165204842 0.41966029989296744 0.31321608059923595 0.38457889227436476 0.6317351933595544 0.2645089650583989 0.38984801704749195 0.32648034770400686 0.467540410393555 0.27454612338975154 0.24354679861109105 0.2396915841934006 Glu-13C01 0.02673803624885302 0.026028494725075856 0.04823190451403234 0.022486037132345062 0.02510261280657001 0.013963914410743499 0.09067985519836662 0.017050709686279808 0.016421953304775222 0.011002432742101867 0.04399015705891213 0.011389744069886265 Glu-13C02 0.003127696894435677 0.008406151817591356 0.055998690783712154 0.020350908026834393 0 0.003582698799030722 0.0668841076598774 0.020472040022456686 0.008817254344904416 0.008855417061377612 0.0444156946828375 0.01735332672737984 Glu-13C03 0.004758838642621844 0 0.010863984461234705 0.2516694896537841 0.006071944496039742 0.00407636761497809 0.04713987807285057 0.25909962362078753 0.00014006381188656525 0.0049073946766827695 0.011654967531321593 0.16215574461978766 Glu-13C04 0 0.0009306893141966622 0.0004913085532518961 0 0.002914857341451855 0.00015511449117128862 0.010003230842539054 0.0010019668278347382 0.004090022788015667 0 0.0070706733251307005 0.002838023282813813 Glu-13C05 0 0 0.004553599390982557 0.004922099136933121 0 0.00040996694795581183 0.0008294901187871164 0.0023899135474918023 0 0 0.0032831445433225124 0.0004275210643369722 Glu-ALL 0.5158570883063948 0.4550256357498313 0.4333555683024496 0.6840074262242614 0.665824608003616 0.2866970273222783 0.6053845789399127 0.6264946014088575 0.49700970464313693 0.2993113678699138 0.3539614357526155 0.4338559439576051 Gly-13C00 0.02408321417459902 0.0700860680444473 0.017420714707843156 0.07560014425131592 0.034890341534993936 0.04566297176212206 0.043972867267703275 0.06986483135544388 0.024126847452530575 0.05048542927681319 0.02752255376062366 0.049984790649871026 Gly-13C01 0.00017137718945858885 0.0025867357700274647 0.0002665066047678693 0.0032498684931297366 0.0032639966042694066 0 0.004353730631510626 0.0013248575974032241 0.0019198483197054132 0.002403680757895027 0.001927595463235993 0.00038836268624796726 Gly-13C02 0.001534194285887675 0 3.5561377938177895e-06 0 0.0022280620112522286 0 0.00024573339919348544 0.0006491193349947413 0.001544784853909135 0 0.0023840487032470393 0.0006917253382174862 Gly-ALL 0.025788785649945283 0.07267280381447476 0.017690777450404843 0.07885001274444565 0.04038240015051557 0.04566297176212206 0.04857233129840739 0.07183880828784185 0.027591480626145123 0.05288911003470822 0.03183419792710669 0.05106487867433648 His-13C00 0 0 0 0 0 0 0 His-13C01 0 0 0 0 0 0 0 His-13C02 0 0 0 0 0 0 0 His-13C03 0 0 0 0 0 0 0 His-13C04 0 0 0 0 0 0 0 His-13C05 0 0 0 0 0 0 0 His-13C06 0 0 0 0 0 0 0 His-ALL 0 0 0 0 0 0 0 Ile-13C00 0.016699168955617374 0.7408327344694159 0.015948310014945045 0.7161561452380429 0.05523860771805032 0.5595839501461042 0.19589697418691285 0.7786361624377044 0.02086917662820714 0.5934991953713779 0.03534867848174124 0.5782665322457318 Ile-13C01 0.002028028845831705 0.05760249207588643 0.002992819636445616 0.051039716882162 0.005668083786167843 0.0567007542283895 0.020282133073835844 0.061656596269240777 0.0024287161193828704 0.051916977599114046 0.0020933540627852357 0.04930634264957426 Ile-13C02 0 0.010093048412607067 0 0.007901650244305902 0 0 0.009332630417510656 0.018305082104978637 0.003291379070708907 0.012498267519798906 0 0.003593904901930275 Ile-13C03 0 0.00010821883468405363 0.004306248389373983 0 0 0 0 0.0019864390506411376 0.003003497182785897 0 0.006425732363511193 0.001715079491017895 Ile-13C04 0 0 0.002666712764872314 0 0 0 0.0013878375273231 0 0 0 0 0.00027295432217855765 Ile-13C05 0 0.001239280240271327 0 3.582263399319393e-05 0.0026754389129842837 0.0003381458138731182 0.0021263719973271034 0.0002876648812549389 0 0.0005212967897799966 0 0.0012301712858464287 Ile-13C06 0 0 0 0.00014313400601903485 0 0.00019635498651173977 0 0.00017433480917436141 0 6.010862422345414e-05 0 0.00021647560202845323 Ile-ALL 0.018727197801449078 0.8098757740328647 0.025914090805636957 0.7752764690045231 0.06358213041720245 0.6168192051748785 0.22902594720290953 0.8610462795529943 0.029592769001084814 0.6584958459042942 0.04386776490803766 0.6346014604983076 Leu-13C00 0.01683335150653187 0.6975820253625404 0.014612614004715788 0.6735175437392162 0.06477741333558272 0.5325970683794056 0.20302023719249362 0.7346987318642727 0.0333900610696493 0.5696899287364273 0.04491350628584666 0.53159904712281 Leu-13C01 0 0.07076691699287628 0.0034347294230563778 0.04140269204885732 0.003795475599279205 0.04439823110713071 0.020166666465193835 0.07318874271265362 0 0.03774104842171011 0 0.055448651143010085 Leu-13C02 0.003473401420499285 0.008240466016475396 0 0.005699143679318712 0.0002934716269640159 0 0 0.0012872822243536522 0.0016621227322515038 0.003039035632606295 0 0.0012132664032857635 Leu-13C03 0.007050561758941043 0.005261148789131381 0.0029319432366117855 0.0022718000657072236 0.005834355077342055 0.002782391956393987 0.0008774820817669448 0.0015536142079580649 0.009693811047404544 0.0006797544136507456 0.008330235359972488 0.001407777249767089 Leu-13C04 0 0 0 0.0009264090905755174 0 0.0009529222460401002 0.003155705106433357 0 0 0.001361013866391996 0 0.00010661025751779212 Leu-13C05 0 0 0.004758330991392669 0.0002481300352785593 0 0 0.002030782761429267 0.0004519267202733246 0 0 0 0.0005816899812747118 Leu-13C06 0 3.8173910533471634e-05 0 0.0003603688978025426 0 0 0 4.538510726284077e-05 0 0.0002737408165847242 0 0.0007091295609062125 Leu-ALL 0.027357314685972196 0.7818887310715571 0.025737617655776618 0.7244260875567561 0.07470071563916798 0.5807306136889704 0.229250873607317 0.8112256828367742 0.044745994849305346 0.6127845218873712 0.053243741645819145 0.5910661717185717 Lys-13C00 0 0.000646900260796065 0 0.0004136343970598722 0 0.00025588821193648574 0 5.388278611139867e-05 0 0.0001169842243041406 0 0.00015976799965529464 Lys-13C01 0 0.00010599617555994708 0 0 0 0.0003576150047677405 0 0.0002587882239377479 0 0.0002242345801762762 0 3.119912833427962e-05 Lys-13C02 0 0.0001198462338843231 0 3.172149764522775e-05 0 8.525785373421356e-05 0 0 0 0.00039418813997065785 0 0 Lys-13C03 0 0.00010674366393773325 0 0.0002059800411815308 0 0.00010347552727546414 0 0.00018729500421194405 0 0.00012369351367425333 0 0.00015353908705748723 Lys-13C04 0 0.00010295945219031262 0 0 0 0 0 4.401703596382361e-05 0 7.141850742290202e-05 0 4.0810779792058816e-05 Lys-13C05 0 0 0 0.00011545752255207381 0 0 0 7.09784663183723e-05 0 0 0 0.0003016172774665054 Lys-13C06 0 0.00014284241949983308 0 0.00023443539076606468 0 0.00017362182694839387 0 0.0003022441264344639 0 5.066065929370663e-05 0 9.773841929144861e-05 Lys-ALL 0 0.0012252882058682143 0 0.0010012288492047693 0 0.0009758584246622979 0 0.0009172056429777504 0 0.0009811796248419366 0 0.0007846726915970742 Malate-13C00 0.003919443276943215 0.0003067483619105504 0.0023368389126143157 0.00031936015321141624 0.003008335411241082 0.00039487662141644923 0.003025619253282216 0.0005077854995719185 0.004641713514639051 0.00032233837875039 0.0027339992894641636 0.0003443281384136456 Malate-13C01 8.629672524476733e-05 1.4780627148929408e-05 0.00047349627731574747 0 7.530140562331726e-05 8.573823051958457e-06 0.0003903863505479138 0 0.00029504640268579186 3.7321260144100926e-05 0.0008160001799103133 6.284498498544932e-05 Malate-13C02 0.00038642102436841285 0 0.00016809085586511803 5.737970525790498e-05 0.00030665126232864374 1.8525181504928755e-05 0.00017015749611680578 4.0893325042699566e-05 0.00013969855693567873 2.4538668983396424e-05 0.00019572537543651174 1.5600361582084532e-05 Malate-13C03 0 0 0 4.985756438827078e-06 0 2.7859424938781213e-05 0 0 0 1.3173109371881646e-05 0 0 Malate-13C04 0 0 0 2.413675600299252e-05 0 0 0 7.459808616613805e-05 0 9.371584240826817e-06 0 2.8228206267435764e-05 Malate-ALL 0.004392161026556395 0.0003215289890594798 0.002978426045795181 0.00040586237091114083 0.003390288079193043 0.0004498350509121176 0.0035861630999469356 0.0006232769107807561 0.005076458474260522 0.00040674300149059583 0.0037457248448109883 0.00045100169124861523 Met-13C00 0.001424866376783723 0.05988099042158355 0 0.06382129666450052 0 0.04775477590065204 0.00873849932178265 0.06620452106097638 0.0020043377165427333 0.0504231820856275 0.0016967640747158317 0.04476482759092992 Met-13C01 0 0.004190292367305764 0 0.003918546353472728 0 0.004329743507428175 0 0.00538599352042005 0.0006689103008252744 0.0032008552516468673 0.0014503100353454393 0.0035977265650315765 Met-13C02 0.0015038131064749503 0.0028460727819382163 0 0.0044844103940675775 0 0.002045869636906083 0.0006545119807599623 0.00265863000455212 0 0.003188565682146119 0 0.0022962982812147407 Met-13C03 0.001008354874607045 0.0005751531947904832 0 0.0005876279301311297 0 2.189340682309495e-05 0.002470201020200555 0.0002862411708710808 0.0013597975919597525 0.00028819515652586344 0.01239453717988566 0.0003797984725480335 Met-13C04 0.0013700833195367155 0.0007874566659674226 0 0 0 0.00038627204133058506 0.0028771552204461324 0.00019275468650784312 0.005300655727344911 0.00016068359857999694 0.0032144031492663573 2.65025171566185e-05 Met-13C05 0.0004394758647358893 0 0 3.641751316467772e-05 0 2.452627043837727e-05 0 0.00011747753080090501 0 0.0002245971580350469 0.0009358144116497726 0 Met-ALL 0.005746593542138324 0.06827996543158543 0 0.07284829885533664 0 0.05456308076357835 0.0147403675431893 0.07484561797412838 0.009333701336672672 0.057486078932561406 0.019691828850863062 0.0510651534268809 OHPro-13C00 0.010071234757736674 0.4872317015188266 0.010706217944023183 0.4698748432066184 0.012510374022101742 0.3453118826629959 0.04039651229759876 0.47693328663091195 0.005461740289795807 0.37304048944368484 0.012937694126809979 0.245394342513271 OHPro-13C01 0.0022702677751710223 0.019515831674142954 0.0018896621708845353 0.0284734374911857 0.002191417464491423 0.01975021597973313 0.0031923321831767376 0.02433389563259675 0.0011628522882196472 0.012675251046194208 0 0.011434531117415062 OHPro-13C02 0 0.002395912433831108 0.00025036420771882157 0 0.00043177385042560715 0.0028076715891102097 0.001989798372876138 0.003191241233493573 0.0007232920337113899 0.007327240958018834 4.185576846031753e-05 0 OHPro-13C03 0 0.0005392318832242946 0 0.0013742335504468893 0 0 0 0.0028202912729336934 0 0.00016568371741557467 0 0.00119198947534974 OHPro-13C04 0 0.0005189367523537778 0 0.007123737528677187 0 0 0 0.0017209548010867787 0 0 0 0.0026906467730551708 OHPro-13C05 0 0 0 0.00011549028354304528 0 0 0 0 0 0.00013232963419007758 0 0.00024369913334748667 OHPro-ALL 0.012341502532907696 0.5102016142623788 0.01284624432262654 0.5069617420604713 0.01513356533701877 0.36786977023183925 0.04557864285365164 0.5089996695710228 0.0073478846117268435 0.3933409947995036 0.012979549895270297 0.2609552090124385 Orn-13C00 0 1.7070497574630232 0 1.6636644176895246 0 0.6506509886770939 0.020637911903759187 0.8635056178166955 0 0.7608988594785452 0 0.6020865856542297 Orn-13C01 0 0.1670718891577568 0 0.10147923269557682 0 0.05965709904248576 0.010722744681383149 0.08054486159096173 0 0.08380343374614302 0 0.04645605609898432 Orn-13C02 0 0 0 0 0 0 0.0050036538469848705 0.01915563279833761 0 0.03397222514914483 0 0.022644625243056864 Orn-13C03 0 0 0 0 0 0.002666331074309684 0.015495219892428115 0 0 0 0 0 Orn-13C04 0 0.010159198197915142 0 0.011799264255860113 0 0 0 0.009499137691252737 0 0 0 0 Orn-13C05 0 0 0 0 0 0.00165943925722519 0 0.0015840849625979822 0 0.0011145111375640863 0 0.0007984625118435341 Orn-ALL 0 1.8842808448186952 0 1.7769429146409617 0 0.7146338580511146 0.05185953032455532 0.9742893348598457 0 0.879789029511397 0 0.6719857295081144 Phe-13C00 0.011263525004954256 0.2676951749871493 0.005406755408946152 0.2697951094378105 0.019424656293573733 0.20222403387684193 0.05661585830002629 0.25613353956827245 0.01013080203068955 0.2010566512381937 0.01623275974807946 0.17722700337009892 Phe-13C01 0.004398366920392411 0.02439201900611186 0.00505358262932315 0.028100216370905772 0.006059872222086581 0.02582993109124576 0.009538814098581715 0.024029006915755397 0.003725059306006775 0.022237662050372645 0.0023587440476307633 0.023727701297957118 Phe-13C02 0 0.00413204366436961 0.0010084075076084438 0 0 0 0 0.001956069366788375 0 0.005268504628009622 0.002826250719549596 0.0022956125025516993 Phe-13C03 0.015294764553417828 0.0003908058852938073 0.016503571634036478 0 0.02079460146037254 0.000711342578050285 0.010719583183712704 0.002620782884889502 0.02717936795311026 0 0.030183602648147005 0.0008114398922719447 Phe-13C04 0.003414408323974572 0.0006832260074528998 0.00221680607652218 0.0002205774135642587 0.008575883124706226 0 0.007247442119770302 0.0008090594151414557 0.009740102813785666 0.0005486636844885263 0.008349225827847116 7.972092574331137e-05 Phe-13C05 0.20312125332249148 0.009924057088227271 0.20205945122185162 0.009374889567808428 0.24698703764316102 0.010962424603551329 0.23563898238157469 0.011064273031703188 0.2944372417290783 0.0098346770872872 0.3454322308772829 0.01280849433703231 Phe-13C06 0.028710886512267803 0.0019131836662151123 0.040165027383150205 0.002336969718848775 0.04231307920350654 0.002401470227503004 0.030982401985669924 0.003310392902735706 0.05827041225892247 0.0029242705944333425 0.04720465061224527 0.002250289146580597 Phe-13C07 0.021694891218940176 0.003021656788248019 0.023891781457583063 0.0033693444347859458 0.03238520653774106 0.0006599708699584162 0.021703277108164554 0.001583356253784299 0.030459214322934282 0.0009559717265462311 0.05174346584631205 0.0014364644171277212 Phe-13C08 0.005295444051720617 1.8164953054931646e-05 0.004428999073812663 0 0.0023291104891353708 0.0006505547005015925 0.006473509912992304 0 0.008011667532874233 2.6452036832617577e-05 0.0027395393837401235 0 Phe-13C09 0.006742899258112343 0 0.0037866692934142706 0.0003317166827506886 0.003821851487357307 6.62555732424241e-05 0.005497705072767326 0.0007216929492552728 0.006835133600670603 0 0.001691593883903189 0.0003611094437239859 Phe-ALL 0.2999364391662715 0.3121703320461228 0.30452105168624827 0.3135288236264743 0.38269129846164035 0.24350598352089473 0.3844175741632598 0.3022281732883257 0.4487890015480722 0.24285285304616389 0.5087620635947375 0.22099783533308762 Pro-13C00 0.012029018209710234 0.1372600496447965 0.009073971542985842 0.13741884593571066 0.01583979748982604 0.10770016442104642 0.03353449568415988 0.14486122995462297 0.010216886712759606 0.11275298056295213 0.010893201439071715 0.10725878021196869 Pro-13C01 0.001701913181009839 0.010202675367211493 0.0008730434967764404 0.003759896883443079 0.0016326600341731276 0.005491418232099888 0.0022430443987593285 0.00965921409149046 0.001432696622889923 0.009067447305610635 0 0.005677624040389999 Pro-13C02 0 0.00258765070964613 0.0008344903965071489 0.0022514537524989248 0.0005381493878656936 0.0012976115643999685 0.0004932797013699698 0 0.0010591572395575223 0.001833364055994476 0 0.004182663590915473 Pro-13C03 0 0 0.0011700069228205694 0.0006452683066433841 0 0.00027926020716398186 0 0.001301583877840597 0 0.0005554816316172852 0 0 Pro-13C04 0 0.0011007483625766058 0 0 0 0 0 0.0007347215277283108 0 0.00017434522572530098 0 0 Pro-13C05 0 0.00031440288159074423 0.002488672870708401 0 0 0.0006562304051788973 0 6.912113026701181e-05 0 0.00010914651041604061 0 0.0005813544963214139 Pro-ALL 0.013730931390720073 0.15146552696582144 0.0144401852297984 0.14407546487829606 0.01801060691186486 0.11542468482988917 0.03627081978428918 0.15662587058194935 0.012708740575207052 0.12449276529231589 0.010893201439071715 0.11770042233959559 Ser-13C00 0.026953981737252768 0.20766624757619193 0.013245685777083075 0.21957119296246005 0.05112176337109895 0.1659255451963929 0.09252955464857832 0.2479132843442098 0.025056886363826896 0.1999558432122359 0.035300920981469905 0.18652105108121828 Ser-13C01 0.0008715929251711218 0.006450844055841038 0.0005342955287013868 0.006060363087391939 0.0025071470921245805 0.007745138381084112 0.005550869980144319 0.002350600136702757 0.0019106788267372057 0.006273808663001057 0.0007145698984183821 0.007849290793187995 Ser-13C02 0 0.002758749326268617 0.00011101683729018825 0 0 0 0 0.0009702295186714425 0 0.004384904512404084 0.0010213847241303186 0 Ser-13C03 0.00044671661236413775 0 0.00010385341185870148 0.0015863875934829356 0 0 0.0006520098862262053 0.0012652114984392734 0.00019660731237881895 0 0.000546855085541676 0.0006283988722685898 Ser-ALL 0.028272291274788027 0.2168758409583016 0.013994851554933352 0.22721794364333492 0.05362891046322353 0.17367068357747703 0.09873243451494883 0.2524993254980233 0.02716417250294292 0.21061455638764104 0.03758373068956028 0.19499874074667486 Succinate-13C00 0.05576713744752695 0.0037442289781234356 0.0336967555123243 0.003575856241169758 0.05516584978377448 0.0025039503509631006 0.0492892665743111 0.0033928033554990558 0.08678468905616113 0.0030631576486356673 0.05512619380236504 0.002916259451630388 Succinate-13C01 0.005177766710207034 0.0006677174645610162 0.0035865762843473818 0.00041587042984800017 0.0026909686168719756 0.0004189959795799868 0.004592375709558063 0.0006143044762591658 0.0033946269475625588 0.000811931385708703 0.00890483452086731 0.0007086494606601924 Succinate-13C02 0.004030978782286827 0.00033037423277960823 0.0025820461991393415 0.00015156410464628502 0.00321257345436313 0.00013979821091786732 0.0029847772983710827 0.00027596816335843466 0.00398721024873903 1.045951006073283e-05 0.005190769089320428 0.00018147099107212046 Succinate-13C03 0 2.83169796857006e-05 0.0001749316497843253 4.085349026641602e-05 0.0007506751525422957 0 0 0 0.00019708685437354364 2.739254748622336e-05 0.001165152389687792 0 Succinate-13C04 0.0005607729110993579 0 0.0006597568035967617 7.016608937273381e-05 0 3.98187756798401e-05 0.0008271498358643101 3.201673883195247e-05 0 0.00017898166029629042 0 2.4322019371285343e-05 Succinate-ALL 0.06553665585112017 0.00477063765514976 0.040700066449192114 0.004254310355303194 0.061820067007551875 0.003102563317140795 0.05769356941810455 0.004315092733948609 0.09436361310683626 0.004091922752187617 0.07038694980224057 0.003830701922733986 Thr-13C00 0.034362166075836656 0.5960572068003073 0.022070511161666518 0.5538502707152165 0.062670721918147 0.41079198003467327 0.1304929166238326 0.645410855383755 0.03261357563766528 0.42462459366486577 0.04747817158746045 0.3415053709084282 Thr-13C01 0 0.027577102985493596 0.001965283679268683 0.025270710343352036 0.005555544305578531 0.026487585163263213 0.009276846581648637 0.03474281290499379 0.002444106164044098 0.017819465381102448 0.0011857773464724647 0.0053341103732977915 Thr-13C02 0 0.0006737074853240462 0 0.0031023667728669424 0 0 0.001045925376804232 0 0 0.004897038201937394 0.003727798129692045 0.002554673654262178 Thr-13C03 0 0.002564421358388058 0 0 0 0.004735290750674508 0.00022799336737363424 0 0 0.00036238755887045326 0 0.0015013079262288494 Thr-13C04 0 0.0001887893191519975 0 0.001573800647381059 0 0 0.001917562030256811 0.0010799826550963976 0 0 0 0.000888109992510962 Thr-ALL 0.034362166075836656 0.6270612279486649 0.024035794840935203 0.5837971484788166 0.06822626622372553 0.442014855948611 0.14296124397991591 0.6812336509438451 0.03505768180170938 0.4477034848067761 0.05239174706362496 0.35178357285472794 Trp-13C00 0 0.0069288165742897615 0 0.008709755550097202 0 0.006314313028000323 0 0.005771808342936044 0 0.0015331586451330476 0 0.0015599541429670838 Trp-13C01 0 0.000591834763342205 0 0 0 0.0004391702247866681 0 0.0016492136492311457 0 0.0008646295053886327 0 0.0008063460996629713 Trp-13C02 0 0.0012062096209608311 0 0.0008272904170751993 0 0.0021262604491593964 0 0 0 0.0023515974619565845 0 0.0058263542334672305 Trp-13C03 0 0.0009028920903737809 0 0.0015232693280768912 0 0 0 0.0063805702653612194 0 0 0 0.0011264274828129024 Trp-13C04 0 0.0009160260290438229 0 0.000976891403057004 0 0.0008169656936670503 0 0.0031582627767664318 0 0.0021332297695549037 0 0.0015772651178096926 Trp-13C05 0 0.0019238924785834747 0 0.00034095216153215007 0 0.0012051770174261616 0 0.0013023784657195888 0 0.002030337274717465 0 0.0013317773652773235 Trp-13C06 0 0.005470134114529216 0 0.0026831781333017685 0 0.0009597736305195439 0 0.004126149572057033 0 0.0013667391366238436 0 0.0014257357038007354 Trp-13C07 0 0.000836906792113107 0 0.0011245652676601472 0 0.0010038392984048929 0 0.0026590242619458962 0 0.004011147380771442 0 0.003089239914820519 Trp-13C08 0 0.0010199287626213602 0 0.003978912428402378 0 0.0024538122259377933 0 0.001483114056686283 0 0.0038546285333598464 0 0.0014632009610960521 Trp-13C09 0 0.00037051945260602377 0 0.008385757114136824 0 0.0006490480050675201 0 0.0006771156042037721 0 0 0 0.0008135355931996035 Trp-13C10 0 0.0019348047534584734 0 0.0038201015048166583 0 0.002514284539369582 0 0.0012393044013509255 0 0.0012856209154691977 0 0.001156717080811797 Trp-13C11 0 0.0008077242235071539 0 0 0 0.0005139416928928023 0 0.0012704743007674216 0 0.0006594868553711439 0 0.001356636313146568 Trp-ALL 0 0.02290968965542921 0 0.032370673308156225 0 0.018996585805231732 0 0.029717415697025757 0 0.020090575478346105 0 0.02153319000887248 Tyr-13C00 0.0014547721583000107 0.11520519865480944 0.000898472849154495 0.11199603696473107 0.0028196842951686164 0.08224933041798674 0.010296202022918666 0.12486786148064455 0.0014753273853471702 0.0883184214708356 0 0.07895387296299239 Tyr-13C01 0.0003903821472773305 0.008211783703444107 0 0.013130070470315069 0.00041176073942195254 0.00850492226080817 0.0017883682828013813 0.013624082871898249 0 0.008669691926154377 0 0.007922696877658557 Tyr-13C02 0 0.0021052307354867054 0 0 0 0.0002547677682693922 0 0 0 0.0010671866523118828 0 0.0010064382326206987 Tyr-13C03 0 1.7883150261122184e-05 0 0.0002011211754984637 0 0 0.00017179351364338675 0.0011213690449964624 0 0.00019904957699679835 0 0.0002027382821516788 Tyr-13C04 0 0 0 3.414768980250957e-05 0 0.0002924835569363835 0 0 0 8.316112379165195e-05 0 0 Tyr-13C05 0 0.0001618791467038018 0 0.0005427200829567775 0 9.497776415042601e-05 0 0.0001660796013942813 0 9.140062711967643e-05 0 0 Tyr-13C06 0 0.0001895579320973245 0 0 0 2.8188028688021426e-05 0 8.99372011358393e-05 0 0.00011561970930986322 0 8.378630489194112e-05 Tyr-13C07 0.0002898757050316538 9.870008941428065e-05 0 1.1105931064392976e-05 0 0.00017290532070356817 0 0.00011412746051651259 0 6.73399227060419e-05 0 0.0003438266152031681 Tyr-13C08 0 0.00011528321876563193 0 0.00013839996592424533 0 0.0001669858948650178 0 0 0.0010780016925758498 0 0 0.00021402541695590563 Tyr-13C09 0.000894294393710191 0.0010719591537585562 0.000640182154178711 0.00011696456020939881 0 0.00022870779231548192 0.0014280559333493621 0.0002310424613949306 0.0011054905371641888 0.0002700904587435576 0 0.0001314672079173184 Tyr-ALL 0.003029324404319186 0.12717747578474098 0.001538655003333206 0.12617056684050193 0.003231445034590569 0.0919932688047232 0.013684419752712796 0.14021450012198083 0.003658819615087209 0.09888196146796946 0 0.08885885190039168 Val-13C00 0.003134246160884187 0.06201112942364296 0.002616226572639 0.06505845823443218 0.008169328533068402 0.057574809655455035 0.01894505474516385 0.07550084619460316 0.004449348234931048 0.057564834396335356 0.0047518565785601785 0.05282042561304257 Val-13C01 0.0005785940130597417 0.005764967347582051 0.000968509414933307 0.004463157715035299 0.0009536861795701189 0.0025796799784079238 0.0011635944272198886 0.004003829982971761 0.0023720664625006215 0.002952127709310583 0.0005960923665771205 0.0035069718254534853 Val-13C02 0.0004950726618874852 0.0007340767694644177 0.0005463844501167223 0.0008611454414898652 0.00023479543201569724 7.6629637286581e-05 0.0005517879226431849 0.0011135906990950076 0.001568918751197648 0.0015267416956791166 0.0020171071527118455 0.0008377287660290458 Val-13C03 0 0 0 0.00012221157316588224 0.0013395270654697668 0.00031548511441247006 0 0.00046907167493872074 0 0 0 0 Val-13C04 0 0.0002091860412302734 0 0 0 0.00015826385395155228 0 0.0005473929448328662 0 1.29394418040128e-05 0 0 Val-13C05 0 4.781412944363054e-05 0 0.00014176555717108119 0 2.6002815848184525e-05 0.0010769223340249636 5.452330683322399e-05 0 7.533828297374077e-05 0 1.587347900920625e-05 Val-ALL 0.004207912835831414 0.06876717371136333 0.004131120437689029 0.07064673852129431 0.010697337210123985 0.06073087105536175 0.02173735942905189 0.08168925480327474 0.008390333448629318 0.06213198152610281 0.007365056097849145 0.057180999683534316 a-glycerol-3P_#1-13C00 0.00469462029409958 0.001211121166059889 0.0018683251084220492 0.0009716059120097863 0.002710309640842408 0.0008343591286880612 0.00502116050132506 0.0007163163603459148 0.006264096140577431 0.0005864127655404579 0 0.0006250225832925019 a-glycerol-3P_#1-13C01 0 0.00017507028412334694 0 0 0.0015194263090908906 2.2740204369378523e-05 0 0 0.001559424359507322 0 0 0 a-glycerol-3P_#1-13C02 0.0002638484664555939 0 0.0009103050640899567 0 0 0 0.0005276529509909813 0 0.0018358786877544888 0.000268551702322197 0 0 a-glycerol-3P_#1-13C03 0 0.00011691400512504606 0 4.9695882181406645e-05 0 0 0 4.267485430985758e-05 0 0 0 1.9906284367234508e-05 a-glycerol-3P_#1-ALL 0.004958468760555173 0.001503105455308282 0.002778630172512006 0.001021301794191193 0.004229735949933299 0.0008570993330574398 0.005548813452316041 0.0007589912146557724 0.009659399187839243 0.0008549644678626548 0 0.0006449288676597364 a-glycerol-3P_#2-13C00 0 0.0020167636265440657 0 0.0009822929151515755 0 0.00038660034891246263 0 0.00044992998916898897 0 0.0005372123380206905 0 0.000627661895020927 a-glycerol-3P_#2-13C01 0 0 0 0.00016071796364545998 0 0.00014011519485364104 0 0.0002715592279869028 0 0 0 0 a-glycerol-3P_#2-13C02 0 0.0001421857841380661 0 0 0 4.237402536912284e-05 0 7.634332740106134e-05 0 5.9244890965338505e-05 0 5.688413094963856e-05 a-glycerol-3P_#2-13C03 0 0.00020249410105681453 0 7.939863253079298e-05 0 0.00014990916523427463 0 0 0 1.2031573030229255e-05 0 2.80429987082651e-05 a-glycerol-3P_#2-ALL 0 0.0023614435117389463 0 0.0012224095113278284 0 0.0007189987343695011 0 0.0007978325445569531 0 0.0006084888020162582 0 0.0007125890246788307 a-ketoglutarate-13C00 0 0.005145856037592126 0 0.003956313927186343 0 0.0008189850614609232 0 0.0002817844217130918 0 0.0013938988967680725 0 0 a-ketoglutarate-13C01 0 0.0021224570572496645 0 0 0 0 0 0 0 0 0 0 a-ketoglutarate-13C02 0 0 0 5.035430470589894e-05 0 0 0 0.00031022132507409553 0 0 0 0 a-ketoglutarate-13C03 0 0 0 0.0015550130345588433 0 0.00010556816190428256 0 7.080381507439332e-05 0 0.00029340703626125987 0 0 a-ketoglutarate-13C04 0 0.0001332809805663235 0 0.0432721242406019 0 0.0004340306000067776 0 0.0011547474252797012 0 9.68530667042585e-05 0 0 a-ketoglutarate-13C05 0 0.00033181025226718656 0 0.001307174470461471 0 5.941159802031258e-06 0 0.0003587801292304796 0 0.00016145679136052838 0 0 a-ketoglutarate-ALL 0 0.007733404327675301 0 0.05014097997751446 0 0.0013645249831740146 0 0.0021763371163717616 0 0.0019456157910941194 0 0 ascorbate-13C00 0.13427119218292452 0.001020460919548456 0.13595792250924388 0.00029739855268076453 0.21208594808896544 0 0.15759285377402998 0 0.2715994200150783 0.0007213552628903881 0.18758541128046724 0.00044584992182760525 ascorbate-13C01 0.011110247239786354 0 0.021967434699386248 0.0005218506711844222 0.017254554408610918 0 0.014392513127737667 0 0.00886704881634325 0.000513450354879275 0.017178517559926634 0 ascorbate-13C02 0.03389389918099706 0 0.029221252157238538 0 0.03342659376073028 0 0.038162561507009085 0 0.04892319009240371 0 0.0003796378194601265 0.0004551961203414321 ascorbate-13C03 0.007718596691878055 0.0007383952713979794 0.002880835676415771 0.0003676854032797546 0 0 0.0048762672157748235 0 0 0 0.0359058501993464 0.0003520323451329671 ascorbate-13C04 0.004866569993761562 0 0.0009205075269840347 0.00042431521241398075 0.009079436398985395 0 0.004993272052218102 0 0 0.00037256010384070673 0 0 ascorbate-13C05 0 0.000557158145766399 0 0.0005376287273263845 0 0 0 0 0 0 0 0 ascorbate-13C06 0 0.0001263597679795838 0 0.0011092912046715253 0 0 0 0 0 0.00042252526828108765 0 0.0003554940691113705 ascorbate-ALL 0.19186050528934753 0.0024423741046924186 0.19094795256926847 0.0032581697715568323 0.27184653265729203 0 0.2200174676767697 0 0.32938965892382527 0.0020298909898914573 0.2410494168592004 0.001608572456413375 bOHbutyrate-13C00 0.024123621505602093 0.010085916438923767 0.03057153571208266 0.008282421509426078 0.037251700951068605 0.005660042488632984 0.03817200680531538 0.007834212115231231 0.039171445122290316 0.004813047671273748 0.04340956398429534 0.004258210198751323 bOHbutyrate-13C01 0.0023902560358578396 0.0006241801600474899 0.0016764452320961474 0.00039689256522986257 0.0022510818975363905 0.0005445343794270108 0.0027397693890851716 0.00019863454828726956 0.001033807103641116 0.0007118516843257158 0 0.00022372872467510874 bOHbutyrate-13C02 0 0 0.003323750947160137 9.100887837943145e-05 0 1.172240240895236e-05 0.0010895278437308394 1.7624405693635688e-05 0 0.00047039099142728673 0 0 bOHbutyrate-13C03 0 3.168481723497007e-05 0 7.362039291050902e-05 0 0.00011676929866482392 0 0.00011745109226245534 0 0 0 0 bOHbutyrate-13C04 0 0 0.0038549527656245226 0 0 0.00010867624248125918 0 0 0 0 0 0 bOHbutyrate-ALL 0.02651387754145993 0.010741781416206226 0.039426684656963466 0.008843943345945881 0.03950278284860499 0.00644174481161503 0.04200130403813139 0.008167922161474592 0.04020525222593143 0.005995290347026751 0.04340956398429534 0.004481938923426431 citrate-13C00 0.0020628713390166385 0.0004590459431910331 0.0015332432421013553 6.899161750443421e-05 0.0018523355077821385 0.0004953264480618334 0.0025500122230630853 0.0002497210794138534 0.002099653585895991 0.0002672194470967818 0.0016544941396451048 0.0003134417743011416 citrate-13C01 0.00047456297538429025 4.2791812442464084e-06 0.00022164335994209882 0.00021448814017368582 0.00026111290844858055 0 0.00043947914735859164 8.028521183470429e-05 2.898381281641927e-05 1.8877156531573374e-05 0.0001932294148112314 0 citrate-13C02 3.8373756344791756e-05 0.00011005233819038147 0.0006170268714136491 0.00014829906745628043 0 3.8366323003746097e-05 0.0004938585328447741 0.0001380048338843104 0.0001816644191659004 4.906670980457528e-05 0 4.642453610250752e-05 citrate-13C03 0 0 0 0 0 0 6.247183109732899e-06 2.306071826239683e-07 0 0 0 2.619788599222369e-05 citrate-13C04 0 7.729970659281904e-05 0 1.3599296535183071e-05 0 5.7735362088402395e-05 0 0 0 4.277921839153869e-05 0 1.310933988355717e-05 citrate-13C05 0 0 0 2.932134657131152e-06 0 0 0 2.1998934105393237e-05 0 0 0 1.7046211281327993e-05 citrate-13C06 0 3.9443400767612505e-05 0 3.3167116098649936e-05 0 6.281897038508235e-07 0 3.073623326476518e-06 0 1.1166504366822507e-05 0 3.491761063011754e-06 citrate-ALL 0.0025758080707457207 0.0006901205699860924 0.002371913473457103 0.00048147737242536454 0.002113448416230719 0.0005920563228578328 0.0034895970863761836 0.0004933142897473619 0.002310301817878311 0.00038910903619129167 0.0018477235544563362 0.00041971150862376975 fumarate-13C00 0.0038206405975671613 0.004932927209963506 0.0025531191249987626 0.002163993114365839 0.0037936316263765934 0.002018618025605738 0.003111552254844793 0.0019491168222710118 0.004282705426208248 0.0017558668553737601 0.005140894263622766 0.0011381724783959052 fumarate-13C01 0.000638096810237385 0.0006843590979147796 0.00043385739251899344 0.00023027789599003453 0 0.00021321020627672774 0.00031508158323280996 0.00012384014542920108 0.00021160802918951356 9.405884639782376e-05 0.00024901099042080687 0.00013279456143736897 fumarate-13C02 0 7.992051877680235e-05 0.00047936956248728044 0.0002905621321002827 0.0003849664757017472 8.975454199056007e-05 0.0003146837059873943 0.0001996017274844855 0 0.00015269378944260097 0.0005557141575551323 0.00013274939302921216 fumarate-13C03 0.000626513795421724 1.624765083521302e-05 0.0005149118962853564 0 0 8.304718537741668e-05 0 2.9758693852495054e-05 0 3.3732218336153458e-06 0 7.915566182450463e-06 fumarate-13C04 0 5.659698577385916e-05 0.0007435619142617165 0.00046592527151061516 0.0009324276128161625 2.310014309596838e-05 0 7.351100013269031e-05 0 3.748776438440263e-05 0 5.237721559521606e-05 fumarate-ALL 0.00508525120322627 0.00577005146326416 0.004724819890552109 0.0031507584139667715 0.005111025714894504 0.0024277301023464108 0.0037413175440649976 0.002375828389169884 0.004494313455397762 0.002043480477432203 0.005945619411598706 0.0014640092146401527 lactate-13C00 3.7571817101564577 0.072316084549604 4.026543478326298 0.0669512035271974 5.903281613977282 0.07940648438789924 5.776610072806342 0.08605691456854157 7.0298206313169995 0.12413591087133473 5.790125017171105 0.11633523671780581 lactate-13C01 0.03615467569807105 0.003000101259328502 0.09395863933353092 0.0026508760590912366 0.21790867631402447 0 0.1386302414371609 0.004950085777123223 0.031626899832754796 0.00244992612488903 0.28032737263122876 0.0013515151693300096 lactate-13C02 0.067621793683208 0 0 0.0027710883006580285 0.050543234703247064 0.0013917118116557646 0 0.0005366331917899736 0.03456539829597727 0 0.06736437578863115 0.0028748915684588456 lactate-13C03 0 0.0006074775126703947 0.01144845149891404 0.016602468923222116 0.0031105059330770192 0.00029835027069455305 0.027726430047179517 0.015501243443908975 0.039735212876750504 0.001136592050228491 0.023230005343400847 0.007817711880905064 lactate-ALL 3.860958179537737 0.07592366332160291 4.131950569158743 0.08897563681016879 6.174844030927631 0.08109654647024955 5.942966744290683 0.10704487698136374 7.135748142322482 0.12772242904645223 6.161046770934366 0.12837935533649972 pyroGlu-13C00 0.050600111729657185 0.41619537412223084 0.028822680861145276 0.35294156012296585 0.08079773755734658 0.29124054967585183 0.12461401472975922 0.41911322476094215 0.04433876620123777 0.3439359204471674 0.044587755187061914 0.3308158419822887 pyroGlu-13C01 0.0022291553909793253 0.03353071082214631 0.003873736945024593 0.0239945727555856 0.006926127387372061 0.022944113096798443 0.01569294229444278 0.03171462571074682 0.003757021987634284 0.023246299700230445 0.0016785572327829485 0.029724076870880183 pyroGlu-13C02 0.020981152273106683 0.1264204210499768 0.010488820960829773 0.1259278390543451 0.03392249459565402 0.10876505030485696 0.0710742989647141 0.14628746165237888 0.01723087782121383 0.12708239266108404 0.0051606102604932575 0.11626677465894573 pyroGlu-13C03 0.0014799900674919938 0.008848017179316178 0.0018820860950733381 0.008907339681807354 0.007697031430871122 0.009498962526786685 0.00624347392291286 0.011897608568610213 0.003534552366850002 0.006074764489470095 0.005427005981912815 0.01015297629389605 pyroGlu-13C04 0 0.002361444172249364 0 0.006697704330691926 0.0005781161933520513 0.003965708721116928 0.0032532048164894637 0.00485652133515659 0.002154066457833113 0 0.003139824393676715 0.0036962816458803623 pyroGlu-13C05 0.0032392686156181905 0.0016899936755199814 0 0.001975713802675538 0.0012815883825170282 0.002839259654129011 0.0024750252672862774 0.0020580155793247156 0 0.001140225719390754 0 0.0002554916117129892 pyroGlu-ALL 0.07852967807685338 0.5892822000298497 0.04506732486207298 0.5204447297480714 0.13120309554711282 0.4402336077970817 0.2233529599956047 0.6159274576071593 0.071015284834769 0.5025329513757893 0.05999375305592765 0.49113968842344113 t-aconitate-13C00 0 0.0006043082553937277 0 0.00010591939949691398 0 0 0 4.537041740280883e-05 0 1.404342866977492e-05 0 3.162049154393492e-05 t-aconitate-13C01 0 0.00012139691898542812 0 3.2289859176579536e-06 0 0 0 0 0 1.9611243637597594e-05 0 0 t-aconitate-13C02 0 0 0 1.2013824264248658e-05 0 0 0 7.011259257214369e-05 0 3.59546489564142e-05 0 2.4534151186936555e-05 t-aconitate-13C03 0 0 0 3.745990800123219e-05 0 0 0 1.8131424965510054e-05 0 5.134355353168549e-05 0 1.6346816797191653e-05 t-aconitate-13C04 0 0 0 0.00042638899431020165 0 0 0 8.842013077592816e-05 0 1.273816441083381e-06 0 9.901366623496824e-06 t-aconitate-13C05 0 2.7138974392930095e-05 0 1.5896302942497566e-05 0 0 0 0 0 8.918297903903242e-06 0 1.2983351094971986e-05 t-aconitate-13C06 0 2.599994955389029e-05 0 0 0 0 0 4.0999158349545436e-05 0 0 0 0 t-aconitate-ALL 0 0.0007788440983259762 0 0.0006009074149327519 0 0 0 0.0002630337240659362 0 0.00013114498914045883 0 9.538617724653194e-05 MS_METABOLITE_DATA_END #METABOLITES METABOLITES_START metabolite_name compound isotopologue isotopologue%type Ala-13C00 Ala 13C00 13C Ala-13C01 Ala 13C01 13C Ala-13C02 Ala 13C02 13C Ala-13C03 Ala 13C03 13C Ala-ALL Ala ALL 13C Arg-13C00 Arg 13C00 13C Arg-13C01 Arg 13C01 13C Arg-13C02 Arg 13C02 13C Arg-13C03 Arg 13C03 13C Arg-13C04 Arg 13C04 13C Arg-13C05 Arg 13C05 13C Arg-13C06 Arg 13C06 13C Arg-ALL Arg ALL 13C Asn-13C00 Asn 13C00 13C Asn-13C01 Asn 13C01 13C Asn-13C02 Asn 13C02 13C Asn-13C03 Asn 13C03 13C Asn-13C04 Asn 13C04 13C Asn-ALL Asn ALL 13C Asp-13C00 Asp 13C00 13C Asp-13C01 Asp 13C01 13C Asp-13C02 Asp 13C02 13C Asp-13C03 Asp 13C03 13C Asp-13C04 Asp 13C04 13C Asp-ALL Asp ALL 13C Cys-13C00 Cys 13C00 13C Cys-13C01 Cys 13C01 13C Cys-13C02 Cys 13C02 13C Cys-13C03 Cys 13C03 13C Cys-ALL Cys ALL 13C GAB-13C00 GAB 13C00 13C GAB-13C01 GAB 13C01 13C GAB-13C02 GAB 13C02 13C GAB-13C03 GAB 13C03 13C GAB-13C04 GAB 13C04 13C GAB-ALL GAB ALL 13C Gln-13C00 Gln 13C00 13C Gln-13C01 Gln 13C01 13C Gln-13C02 Gln 13C02 13C Gln-13C03 Gln 13C03 13C Gln-13C04 Gln 13C04 13C Gln-13C05 Gln 13C05 13C Gln-ALL Gln ALL 13C Glu-13C00 Glu 13C00 13C Glu-13C01 Glu 13C01 13C Glu-13C02 Glu 13C02 13C Glu-13C03 Glu 13C03 13C Glu-13C04 Glu 13C04 13C Glu-13C05 Glu 13C05 13C Glu-ALL Glu ALL 13C Gly-13C00 Gly 13C00 13C Gly-13C01 Gly 13C01 13C Gly-13C02 Gly 13C02 13C Gly-ALL Gly ALL 13C His-13C00 His 13C00 13C His-13C01 His 13C01 13C His-13C02 His 13C02 13C His-13C03 His 13C03 13C His-13C04 His 13C04 13C His-13C05 His 13C05 13C His-13C06 His 13C06 13C His-ALL His ALL 13C Ile-13C00 Ile 13C00 13C Ile-13C01 Ile 13C01 13C Ile-13C02 Ile 13C02 13C Ile-13C03 Ile 13C03 13C Ile-13C04 Ile 13C04 13C Ile-13C05 Ile 13C05 13C Ile-13C06 Ile 13C06 13C Ile-ALL Ile ALL 13C Leu-13C00 Leu 13C00 13C Leu-13C01 Leu 13C01 13C Leu-13C02 Leu 13C02 13C Leu-13C03 Leu 13C03 13C Leu-13C04 Leu 13C04 13C Leu-13C05 Leu 13C05 13C Leu-13C06 Leu 13C06 13C Leu-ALL Leu ALL 13C Lys-13C00 Lys 13C00 13C Lys-13C01 Lys 13C01 13C Lys-13C02 Lys 13C02 13C Lys-13C03 Lys 13C03 13C Lys-13C04 Lys 13C04 13C Lys-13C05 Lys 13C05 13C Lys-13C06 Lys 13C06 13C Lys-ALL Lys ALL 13C Malate-13C00 Malate 13C00 13C Malate-13C01 Malate 13C01 13C Malate-13C02 Malate 13C02 13C Malate-13C03 Malate 13C03 13C Malate-13C04 Malate 13C04 13C Malate-ALL Malate ALL 13C Met-13C00 Met 13C00 13C Met-13C01 Met 13C01 13C Met-13C02 Met 13C02 13C Met-13C03 Met 13C03 13C Met-13C04 Met 13C04 13C Met-13C05 Met 13C05 13C Met-ALL Met ALL 13C OHPro-13C00 OHPro 13C00 13C OHPro-13C01 OHPro 13C01 13C OHPro-13C02 OHPro 13C02 13C OHPro-13C03 OHPro 13C03 13C OHPro-13C04 OHPro 13C04 13C OHPro-13C05 OHPro 13C05 13C OHPro-ALL OHPro ALL 13C Orn-13C00 Orn 13C00 13C Orn-13C01 Orn 13C01 13C Orn-13C02 Orn 13C02 13C Orn-13C03 Orn 13C03 13C Orn-13C04 Orn 13C04 13C Orn-13C05 Orn 13C05 13C Orn-ALL Orn ALL 13C Phe-13C00 Phe 13C00 13C Phe-13C01 Phe 13C01 13C Phe-13C02 Phe 13C02 13C Phe-13C03 Phe 13C03 13C Phe-13C04 Phe 13C04 13C Phe-13C05 Phe 13C05 13C Phe-13C06 Phe 13C06 13C Phe-13C07 Phe 13C07 13C Phe-13C08 Phe 13C08 13C Phe-13C09 Phe 13C09 13C Phe-ALL Phe ALL 13C Pro-13C00 Pro 13C00 13C Pro-13C01 Pro 13C01 13C Pro-13C02 Pro 13C02 13C Pro-13C03 Pro 13C03 13C Pro-13C04 Pro 13C04 13C Pro-13C05 Pro 13C05 13C Pro-ALL Pro ALL 13C Ser-13C00 Ser 13C00 13C Ser-13C01 Ser 13C01 13C Ser-13C02 Ser 13C02 13C Ser-13C03 Ser 13C03 13C Ser-ALL Ser ALL 13C Succinate-13C00 Succinate 13C00 13C Succinate-13C01 Succinate 13C01 13C Succinate-13C02 Succinate 13C02 13C Succinate-13C03 Succinate 13C03 13C Succinate-13C04 Succinate 13C04 13C Succinate-ALL Succinate ALL 13C Thr-13C00 Thr 13C00 13C Thr-13C01 Thr 13C01 13C Thr-13C02 Thr 13C02 13C Thr-13C03 Thr 13C03 13C Thr-13C04 Thr 13C04 13C Thr-ALL Thr ALL 13C Trp-13C00 Trp 13C00 13C Trp-13C01 Trp 13C01 13C Trp-13C02 Trp 13C02 13C Trp-13C03 Trp 13C03 13C Trp-13C04 Trp 13C04 13C Trp-13C05 Trp 13C05 13C Trp-13C06 Trp 13C06 13C Trp-13C07 Trp 13C07 13C Trp-13C08 Trp 13C08 13C Trp-13C09 Trp 13C09 13C Trp-13C10 Trp 13C10 13C Trp-13C11 Trp 13C11 13C Trp-ALL Trp ALL 13C Tyr-13C00 Tyr 13C00 13C Tyr-13C01 Tyr 13C01 13C Tyr-13C02 Tyr 13C02 13C Tyr-13C03 Tyr 13C03 13C Tyr-13C04 Tyr 13C04 13C Tyr-13C05 Tyr 13C05 13C Tyr-13C06 Tyr 13C06 13C Tyr-13C07 Tyr 13C07 13C Tyr-13C08 Tyr 13C08 13C Tyr-13C09 Tyr 13C09 13C Tyr-ALL Tyr ALL 13C Val-13C00 Val 13C00 13C Val-13C01 Val 13C01 13C Val-13C02 Val 13C02 13C Val-13C03 Val 13C03 13C Val-13C04 Val 13C04 13C Val-13C05 Val 13C05 13C Val-ALL Val ALL 13C a-glycerol-3P_#1-13C00 a-glycerol-3P_#1 13C00 13C a-glycerol-3P_#1-13C01 a-glycerol-3P_#1 13C01 13C a-glycerol-3P_#1-13C02 a-glycerol-3P_#1 13C02 13C a-glycerol-3P_#1-13C03 a-glycerol-3P_#1 13C03 13C a-glycerol-3P_#1-ALL a-glycerol-3P_#1 ALL 13C a-glycerol-3P_#2-13C00 a-glycerol-3P_#2 13C00 13C a-glycerol-3P_#2-13C01 a-glycerol-3P_#2 13C01 13C a-glycerol-3P_#2-13C02 a-glycerol-3P_#2 13C02 13C a-glycerol-3P_#2-13C03 a-glycerol-3P_#2 13C03 13C a-glycerol-3P_#2-ALL a-glycerol-3P_#2 ALL 13C a-ketoglutarate-13C00 a-ketoglutarate 13C00 13C a-ketoglutarate-13C01 a-ketoglutarate 13C01 13C a-ketoglutarate-13C02 a-ketoglutarate 13C02 13C a-ketoglutarate-13C03 a-ketoglutarate 13C03 13C a-ketoglutarate-13C04 a-ketoglutarate 13C04 13C a-ketoglutarate-13C05 a-ketoglutarate 13C05 13C a-ketoglutarate-ALL a-ketoglutarate ALL 13C ascorbate-13C00 ascorbate 13C00 13C ascorbate-13C01 ascorbate 13C01 13C ascorbate-13C02 ascorbate 13C02 13C ascorbate-13C03 ascorbate 13C03 13C ascorbate-13C04 ascorbate 13C04 13C ascorbate-13C05 ascorbate 13C05 13C ascorbate-13C06 ascorbate 13C06 13C ascorbate-ALL ascorbate ALL 13C bOHbutyrate-13C00 bOHbutyrate 13C00 13C bOHbutyrate-13C01 bOHbutyrate 13C01 13C bOHbutyrate-13C02 bOHbutyrate 13C02 13C bOHbutyrate-13C03 bOHbutyrate 13C03 13C bOHbutyrate-13C04 bOHbutyrate 13C04 13C bOHbutyrate-ALL bOHbutyrate ALL 13C citrate-13C00 citrate 13C00 13C citrate-13C01 citrate 13C01 13C citrate-13C02 citrate 13C02 13C citrate-13C03 citrate 13C03 13C citrate-13C04 citrate 13C04 13C citrate-13C05 citrate 13C05 13C citrate-13C06 citrate 13C06 13C citrate-ALL citrate ALL 13C fumarate-13C00 fumarate 13C00 13C fumarate-13C01 fumarate 13C01 13C fumarate-13C02 fumarate 13C02 13C fumarate-13C03 fumarate 13C03 13C fumarate-13C04 fumarate 13C04 13C fumarate-ALL fumarate ALL 13C lactate-13C00 lactate 13C00 13C lactate-13C01 lactate 13C01 13C lactate-13C02 lactate 13C02 13C lactate-13C03 lactate 13C03 13C lactate-ALL lactate ALL 13C pyroGlu-13C00 pyroGlu 13C00 13C pyroGlu-13C01 pyroGlu 13C01 13C pyroGlu-13C02 pyroGlu 13C02 13C pyroGlu-13C03 pyroGlu 13C03 13C pyroGlu-13C04 pyroGlu 13C04 13C pyroGlu-13C05 pyroGlu 13C05 13C pyroGlu-ALL pyroGlu ALL 13C t-aconitate-13C00 t-aconitate 13C00 13C t-aconitate-13C01 t-aconitate 13C01 13C t-aconitate-13C02 t-aconitate 13C02 13C t-aconitate-13C03 t-aconitate 13C03 13C t-aconitate-13C04 t-aconitate 13C04 13C t-aconitate-13C05 t-aconitate 13C05 13C t-aconitate-13C06 t-aconitate 13C06 13C t-aconitate-ALL t-aconitate ALL 13C METABOLITES_END #END