metabolite_name V09 MUT09 MUT07 MUT06 WT02 WT07 WT05 MUT04 V07 MUT08 QC002 WT04 WT06 V02 WT03 MUT10 WT10 WT01 MUT05 WT08 V05 QC003 MUT03 WT09 V10 V06 V04 V01 MUT02 V03 MUT01 V08 QC004 Blank001 QC005 HR_11_IDH1 HR_09_IDH1 HR_02_WT HR_05_IDH2 HR_07_IDH2 HR_10_IDH1 QC06 HR_08_IDH2 HR_12_IDH1 HR_03_WT HR_06_IDH2 HR_04_WT HR_01_WT Blank002 QC007 QC008 CS49_MUT09_48 CS43_MUT03_48 CS56_V06_48 CS53_V03_48 CS37_WT07_48 CS47_MUT07_48 CS58_V08_48 CS51_V01_48 CS33_WT03_48 CS44_MUT04_48 QC009 CS41_MUT01_48 CS39_WT09_48 CS52_V02_48 CS48_MUT08_48 CS42_MUT02_48 CS57_V07_48 CS45_MUT05_48 CS34_WT04_48 CS36_WT06_48 CS50_MUT10_48 QC010 CS40_WT10_48 CS38_WT08_48 CS55_V05_48 CS59_V09_48 CS54_V04_48 CS35_WT05_48 CS46_MUT06_48 CS32_WT02_48 CS60_V10_48 CS31_WT01_48 QC011 Blank003 Asp TIC Results 62067.0586 68997.33993 75371.38813 70801.55076 57925.81691 54193.40238 70498.59874 75943.91992 64545.09647 85047.2726 447866.2448 48154.70257 57527.10983 195115.1489 109874.8587 24718.9052 42896.08221 65546.02794 66255.50981 52567.21863 59880.8502 517862.6181 184595.3644 68731.63646 69226.80163 69381.23022 50766.08415 66367.8631 89576.99165 75550.29143 82785.95803 54247.98495 429798.3593 5306.82436 508958.2916 609124.4604 199059.426 498470.7185 114465.8525 294486.5884 148462.0829 830592.7041 1251014.126 30251.68959 135569.8079 493269.6016 3450604.433 207144.2845 10665.68855 788290.8294 620218.6602 22127.07494 55695.28688 27501.0992 48423.55338 21037.22373 22634.30231 24947.40435 24803.51163 33477.10421 15504.29583 586575.8508 23392.70818 22287.02709 22427.61428 22521.52089 31661.43607 30064.90361 20797.25454 20106.64763 23075.75919 20365.98566 513001.8396 20638.83746 23649.2834 29344.76887 26826.7331 23241.50115 24558.9413 18890.38544 31039.5341 22522.23797 19136.39006 498748.7566 14472.85897 Asp EIC Results 3662.335785 4347.787233 4583.813687 4203.923077 3334 3182 4256.284942 4528.721112 3918 4911.015217 28168 2718.296788 3421.644581 12155.11512 6705.797197 1454 2236.269006 3674.666291 3960.195702 3085.191925 3243 33897.15629 11989.50018 4013.754717 3994.741025 4002.483707 3013.425367 4072 5499.242766 4173.888452 4778 3045 27344 34 32648 40897.83605 11823.08569 33519.62848 6254.089803 18889.7325 8699.05017 58439.72847 89508.51923 1287.386974 7797.942518 32259.55409 278317.2429 13213.95684 25.93100988 54622.76509 36722.98839 1165 3313.723305 1411 2723 1062 1194 1264 1441.993592 1879 1042.273538 34674.55438 1327 1135 1103 1242 1951 1519 1009 1220 1151 1152 31354.5028 911 1221 1578 1389.318707 1234 1097 951.2824659 1816.250938 1046 1005 29754.16455 65 2HG TIC Results 2379.6125 929937.0141 998440.9202 1069168.264 1766.103125 1957.321316 2171.235413 1099299.67 1892.113359 1145497.368 1622118.682 1975.7625 1905.813369 1984.771547 1546.773382 345366.8361 1970.146877 1600.292662 1295079.348 1979.033494 1900.014468 2014774.842 1280467.562 3027.920939 2127.9625 2185.223102 1412.21632 1225.53659 793902.9575 2112.97766 1011826.018 1652.465949 1557615.714 5827.246875 2067240.808 170291.5777 3583177.525 5628.459375 110893.0043 988477.7222 62002.62615 2617796.438 3029049.197 77559.86208 7178.801639 1450304.234 11398.43176 4855.188278 5736.79375 2501630.235 2308320.5 677076.7539 157407.1728 970.9440275 1329.561653 1737.817176 767532.3147 3001.959482 1516.810698 1431.522293 340394.3165 2295711.772 410910.7765 1573.514574 1086.680241 628545.7785 197697.5771 1267.5 352363.9151 1232.087565 1126.125 387689.2244 2118710.26 1059.402263 939.9966076 1131.44375 1327.84375 1295.81875 1672.782695 714603.4415 2195.4 1634.450019 2509.975414 2056238.225 4077.5625 2HG EIC Results 270 138357.9143 149553.5296 167596.3631 229 191.0320803 227 165613.6082 202 174699.255 247344.8571 269 293 153.6153846 106 46323.90963 188 208 193454.2214 224.7783898 217.5384615 313709.2498 193792 309 186.7152671 208 147 114.9890625 113573.8189 99.34615385 149099.4184 185 237473.5094 350 310272 23652.43084 621035.4005 412.2819881 15248.91958 152807.3429 8894.017817 424871.6039 514037.0952 10228.53963 296.2179893 229797.9352 2742.899876 398.9230769 24.56854897 402789.2198 337960.5409 91317.61085 20168.79702 172 97 187 105992.4709 214 100 174.4615385 43709.26145 333160.3944 52373.78773 229.4774348 95 86368 25699.3888 111 44661.99109 140 219 50886.54115 300712.5488 252 202 79 139 101 88 96216.04266 136 39.28245356 416.0769231 286699.1261 277 Glu TIC Results 6571665.097 2105616.63 2428900.625 2636272.734 5319126.759 4913475.068 6259518.76 2824469.46 6210461.425 3010281.962 492659.6078 5720729.838 5446163.308 7399968.004 6710379.362 325767.923 2744293.793 5883039.872 2628371.845 5277603.5 5635202.765 598050.7795 3618888.413 6774789.104 5235173 7130334.299 5388128.67 6177417.333 3911635.827 6304200.431 2773219.482 5752449.506 494130.8833 2445.575749 608088.0796 5657123.897 5421979.081 6700558.637 2476359.879 5688185.037 2886950.29 899682.6277 7693632.984 1022163.621 2983100.095 7513739.861 15857911.82 3486475.573 3341.736286 861844.5374 782679.0936 402768.302 917124.0403 916524.7667 896398.7647 820508.4048 371541.9572 627541.9594 1423014.712 667199.7068 229728.4523 716686.8442 545835.1978 684639.2191 480477.1016 448996.381 335738.4797 1373593.676 442350.3798 479408.5638 749449.6118 276934.2842 639601.1459 912840.1011 811977.5594 1048159.737 801784.0505 523768.2465 906725.4161 296481.0148 629705.2325 1078039.936 981691.4646 611840.7043 2820.99936 Glu EIC Results 990626.18 275121.6334 327978.707 351267.1984 775707.6208 718882.7063 948702.1825 375655.602 958285.8009 411560.9846 56331.95826 820832.6422 779101.1062 1121221.964 1010130.576 36423.1178 354539.6253 863701.3527 344749.4315 786260.5234 827220.0986 69132.46603 509222.163 1025686.712 767966.1044 1096147.9 796064.9075 934035.5617 553716.6715 967320.9254 379383.6661 856029.8588 57421.82176 173.1177599 68298.64274 837782.48 830819.2785 1052077.06 338847.0227 879267.292 410022.5336 114711.7821 1228190.706 131308.0108 423002.6766 1211303.961 2735000.716 493847.4982 52.31457294 107096.0611 85587.29888 43606.31775 104180.3391 103251.6172 98985.38524 93037.50765 38941.82004 68263.01578 161903.8392 72772.85632 23784.77659 79924.08804 59903.28215 74874.48183 52460.39831 47686.8242 35286.04402 159346.2915 47240.15665 49911.82271 81988.5512 28334.90626 68413.25009 102408 88845.668 120836.1069 89995.74745 56981.70133 102053.4034 30213.95252 68351.40361 122740.3042 110601.1028 66061.18033 129 Ratio of 2HG/Glu TIC 0.000362102 0.44164593 0.411067011 0.405560567 0.000332029 0.000398358 0.000346869 0.38920572 0.000304666 0.380528264 3.292574947 0.000345369 0.000349937 0.000268214 0.000230505 1.060162194 0.000717907 0.000272018 0.492730642 0.000374987 0.000337169 3.368902628 0.353828971 0.00044694 0.000406474 0.000306469 0.000262098 0.00019839 0.202959323 0.00033517 0.364856091 0.000287263 3.152233075 2.38277096 3.399574629 0.030102147 0.660861555 0.000839999 0.04478065 0.17377735 0.02147686 2.909688769 0.393708564 0.075878128 0.00240649 0.193020288 0.000718785 0.001392578 1.716710494 2.902646738 2.949255345 1.681057696 0.17163128 0.001059376 0.001483226 0.002117976 2.065802529 0.004783679 0.001065914 0.002145568 1.481724676 3.203228566 0.752811065 0.002298312 0.002261669 1.399890523 0.588843964 0.000922762 0.796571974 0.002570016 0.001502603 1.39993221 3.312549193 0.001160556 0.001157663 0.001079457 0.001656111 0.002474031 0.001844861 2.410283984 0.003486393 0.001516131 0.002556786 3.360741137 1.445431913 Ratio of 2HG/Glu EIC 0.000272555 0.502897255 0.455985484 0.477119309 0.000295214 0.000265735 0.000239274 0.440865536 0.000210793 0.424479631 4.390844286 0.000327716 0.000376074 0.000137007 0.000104937 1.271827137 0.000530265 0.000240824 0.561144425 0.000285883 0.000262975 4.537799211 0.38056474 0.000301262 0.00024313 0.000189755 0.000184658 0.00012311 0.205111792 0.000102702 0.393004317 0.000216114 4.135596924 2.021745199 4.542872121 0.028232186 0.74749758 0.000391874 0.045002371 0.173789409 0.021691534 3.703818354 0.418531986 0.077897301 0.000700275 0.189711206 0.001002888 0.000807786 0.469631072 3.761008721 3.948723062 2.09413717 0.193595041 0.001665833 0.000979943 0.002009942 2.721816052 0.003134933 0.000617651 0.002397344 1.837699054 4.16846038 0.874305812 0.003064828 0.00181089 1.811150175 0.728315954 0.000696596 0.94542428 0.002804947 0.002671105 1.795895871 4.395530814 0.002460745 0.002273606 0.000653778 0.001544517 0.001772499 0.000862294 3.184490431 0.001989718 0.000320045 0.00376196 4.339903172 2.147286822 metabolite_name Asp TIC Results Asp EIC Results 2HG TIC Results 2HG EIC Results Glu TIC Results Glu EIC Results Ratio of 2HG/Glu TIC Ratio of 2HG/Glu EIC