metabolite_name bileacid_Exp1_1_EER bileacid_Exp1_2_EER bileacid_Exp1_3_EER bileacid_Exp1_4_EER bileacid_Exp1_5_EER bileacid_Exp1_6_EER bileacid_Exp1_7_EER bileacid_Exp1_8_EER bileacid_Exp1_9_EER bileacid_Exp1_10_Therapy bileacid_Exp1_11_Therapy bileacid_Exp1_12_Therapy bileacid_Exp1_13_Therapy bileacid_Exp1_14_Therapy bileacid_Exp1_15_Therapy bileacid_Exp1_16_Therapy bileacid_Exp1_17_Therapy bileacid_Exp1_18_Prevention bileacid_Exp1_19_Prevention bileacid_Exp1_20_Prevention bileacid_Exp1_21_Prevention bileacid_Exp1_22_Prevention bileacid_Exp1_23_Prevention bileacid_Exp1_24_Prevention bileacid_Exp1_25_Prevention bileacid_Exp1_26_GUT103 bileacid_Exp1_27_GUT103 bileacid_Exp1_28_GUT103 bileacid_Exp1_29_GUT103 bileacid_Exp1_30_GUT103 bileacid_Exp2_1_Hu+PBS_week2 bileacid_Exp2_2_Hu+PBS_week2 bileacid_Exp2_3_Hu+PBS_week2 bileacid_Exp2_4_Hu+PBS_week2 bileacid_Exp2_5_Hu+PBS_week2 bileacid_Exp2_6_Hu+PBS_week2 bileacid_Exp2_7_Hu+PBS_week2 bileacid_Exp2_8_Hu+PBS_week2 bileacid_Exp2_9_Hu+PBS_week2 bileacid_Exp2_10_Hu+PBS_week2 bileacid_Exp2_11_Hu+PBS_week2 bileacid_Exp2_12_Hu+GUT108_week2 bileacid_Exp2_13_Hu+GUT108_week2 bileacid_Exp2_14_Hu+GUT108_week2 bileacid_Exp2_15_Hu+GUT108_week2 bileacid_Exp2_16_Hu+GUT108_week2 bileacid_Exp2_17_Hu+GUT108_week2 bileacid_Exp2_18_Hu+GUT108_week2 bileacid_Exp2_19_Hu+GUT108_week2 bileacid_Exp2_20_Hu+GUT108_week2 bileacid_Exp2_21_Hu+GUT108_week2 bileacid_Exp2_22_Hu+GUT108_week2 bileacid_Exp2_1_Hu+PBS_week4 bileacid_Exp2_2_Hu+PBS_week4 bileacid_Exp2_3_Hu+PBS_week4 bileacid_Exp2_4_Hu+PBS_week4 bileacid_Exp2_5_Hu+PBS_week4 bileacid_Exp2_6_Hu+PBS_week4 bileacid_Exp2_7_Hu+PBS_week4 bileacid_Exp2_8_Hu+PBS_week4 bileacid_Exp2_9_Hu+PBS_week4 bileacid_Exp2_10_Hu+PBS_week4 bileacid_Exp2_11_Hu+PBS_week4 bileacid_Exp2_12_Hu+GUT108_week4 bileacid_Exp2_13_Hu+GUT108_week4 bileacid_Exp2_14_Hu+GUT108_week4 bileacid_Exp2_15_Hu+GUT108_week4 bileacid_Exp2_16_Hu+GUT108_week4 bileacid_Exp2_17_Hu+GUT108_week4 bileacid_Exp2_18_Hu+GUT108_week4 bileacid_Exp2_19_Hu+GUT108_week4 bileacid_Exp2_20_Hu+GUT108_week4 bileacid_Exp2_21_Hu+GUT108_week4 bileacid_Exp2_22_Hu+GUT108_week4 α-Muricholate 11.19 12.87 16.63 21.51 24.23 30.14 32.39 44.38 48.05 1151.67 1179.31 1327.85 1351.37 1364.01 3030.23 3599.01 5696.62 765.6 954.2 1026.58 1063.96 1087.52 1331.13 1384.41 611.7 1331.56 1382.54 2712.7 2840.91 β-Muricholate 143.16 186.57 228.41 300.75 433.06 504.51 572.8 600.76 711.07 21248.93 21730.57 22058.5 23876.62 26698.31 33831.56 39948.9 52330.96 12629.71 14511.23 16633.13 17469.43 20152.17 21481.76 24101.83 14423.1 24116.84 30952.8 41582.39 43654.28 Cholate 226.39 336.45 363.73 423.5 782.96 949.8 1053.65 1171.4 1561.06 1188.06 1260.67 1494.23 1642.78 1890.95 3787.25 4301.72 1688.84 1773.7 2070.24 2456.72 2525.52 2889.57 3546.57 1772.28 2912.23 4213.43 4240.56 4370.41 Chenodeoxycholate 5.86 6.61 7.99 11.32 15.65 22.03 23.11 37.1 38.17 145.28 172.95 183.69 212.43 220.6 393.37 452.7 584.26 241.65 254.13 278.7 324.78 356.11 371.77 388.44 149.56 166.16 206.74 466.14 485.67 Lithocholate 53.43 74.76 97.12 100.9 106.66 127.92 131.51 219.67 242.37 141.6 147.73 174.2 184.04 192.02 206.18 273.79 343.14 220.31 253.94 265.9 268.86 326.39 338.78 422.93 158.11 205 225.49 350.64 376.56 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.42 0 0 0 0 0 0 0 0 0 0 2.644 0 21.386 1.002 5.623 0 11.086 9.764 5.081 0.084 8.109 11.093 14.072 Ursodeoxycholate 4.35 6.28 8.23 14.33 18.21 24.55 24.6 26.82 27.42 253.09 334.54 397.1 418.62 502.5 705.98 810.97 836.86 208.67 250.65 282.79 327.67 378.14 402.18 403.83 214.69 299.07 488.76 868.8 936.37 Deoxycholate 3.95 4.03 4.08 4.8 8.2 8.63 9.75 0.84 2 2.03 2.64 3.59 4.61 2.15 5.98 6.06 8.18 11.24 42.78 3.05 6.44 3.93 5.3 2.83 0.461 0.222 0.282 0.353 0.117 0 0.043 0.082 0.206 0.056 0.076 0.262 0.271 0.328 0.42 0.207 0.099 0.063 0.058 0.044 0.547 0.256 0.372 0 0.075 0.149 0.194 0.047 0.108 0.068 0.134 101.013 7.052 346.348 28.848 133.854 31.253 569.657 437.305 360.985 7.515 128.193 490.691 561.32 metabolite_name retention time quantified m/z PubChem_CID KEGG_ID α-Muricholate 14 407.3 5283852 C17647 β-Muricholate 14 407.3 5283853 C17726 Cholate 14 407.3 221493 C00695 Chenodeoxycholate 14 391.3 10133 C02528 Lithocholate 14 375.3 9903 C03990 Ursodeoxycholate 14 391.3 31401 C07880 Deoxycholate 14 391.3 222528 C04483