Summary of Study ST000235
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000188. The data can be accessed directly via it's Project DOI: 10.21228/M8ZK5B This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000235 |
| Study Title | Sprague Dawley rats Nicotine alters brain oxidative metabolism |
| Study Summary | Adult (14 weeks old) Sprague-Dawley rats showing at least three consecutive normal periods (4 day) of estrous cycles were randomly assigned to four groups: 1: saline, 2: nicotine (6 mg/kg), 3: OC and 4: nicotine (6 mg/kg) + OC. Rats were exposed to these treatments for a month. At the end of treatments, hippocampus was obtained, immediately frozen in liquid nitrogen. We are sending one side of hippocampi to Southeast Center for Integrated Metabolomics for analysis at the University of Florida. |
| Institute | University of Florida |
| Department | SECIM |
| Last Name | Garrett |
| First Name | Tim |
| Address | 2004 Mowry Road |
| tgarrett@ufl.edu | |
| Phone | 3526279177 |
| Submit Date | 2015-08-25 |
| Total Subjects | 32 |
| Study Comments | Saline, Nicotine, Oral contraceptives, Nicotine + oral contraceptives |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Uploaded File Size | 4.2 G |
| Analysis Type Detail | LC-MS |
| Release Date | 2016-09-23 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN000353 | AN000354 |
|---|---|---|
| Analysis type | MS | MS |
| Chromatography type | Reversed phase | Reversed phase |
| Chromatography system | Thermo Dionex Ultimate 3000 | Thermo Dionex Ultimate 3000 |
| Column | ACE Excel 2 C18-PFP (100 x 2.1mm, 2um) | ACE Excel 2 C18-PFP (100 x 2.1mm, 2um) |
| MS Type | ESI | ESI |
| MS instrument type | Orbitrap | Orbitrap |
| MS instrument name | Thermo Q Exactive Orbitrap | Thermo Q Exactive Orbitrap |
| Ion Mode | POSITIVE | NEGATIVE |
| Units | Peak area | Peak area |
