Summary of Study ST000930

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000644. The data can be accessed directly via it's Project DOI: 10.21228/M8F380 This work is supported by NIH grant, U2C- DK119886.

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Study IDST000930
Study TitleDefine alterations in the gut metabolome of mice infected with C. difficile
Study TypeTime course experiment
Study SummaryC57BL/6 mice were treated with antibiotics to make them susceptible to C. difficile. Mice were challenged with C. difficile and the infection was monitored for 30 hours post challenge. Mice were sacrificed at 0 hr, 12 hr, 24 hr, and 30 hr post challenge with C. difficile and gut content was collected for untargeted metabolomic analysis. The aim of this project was to define the gut metabolome throughout C. difficile infection.
Institute
North Carolina State University
DepartmentPHP
LaboratoryTheriot
Last NameTheriot
First NameCasey
Address1051 William Moore Drive
Emailcmtherio@ncsu.edu
Phone919-513-0711
Submit Date2018-02-26
Num Groups4
Total Subjects31
Num Males16
Num Females15
Analysis Type DetailLC-MS
Release Date2018-03-15
Release Version1
Casey Theriot Casey Theriot
https://dx.doi.org/10.21228/M8F380
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN001524
Analysis type MS
Chromatography type Reversed phase
Chromatography system Waters Acquity
Column Waters Acquity BEH C8 (100 x 2mm,1.7um)
MS Type ESI
MS instrument type Orbitrap
MS instrument name Thermo Q Exactive Orbitrap
Ion Mode UNSPECIFIED
Units scaled intensity
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