Summary of Study ST001643
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001051. The data can be accessed directly via it's Project DOI: 10.21228/M8V702 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001643 |
| Study Title | Deletion of the diabetes candidate gene Slc16a13 in mice |
| Study Summary | The metabolome of plasma and liver lysates of Slc16a13 knockout mice was analyzed. Genome-wide association studies identified SLC16A13 as novel target gene in type 2 diabetes. The SLC16A13 gene encodes for SLC16A13/MCT13, a member of the solute carrier 16 family of monocarboxylate transporters. So far, biology and physiological function of SLC16A13 is unknown. Deletion of Slc16a13 is hypothezised to affect intrahepatocellular monocarboxylate availability, that drives increased oxidative phosphorylation, while reducing hepatic lipid content, thereby attenuating hepatic insulin resistance. |
| Institute | University of California, Davis |
| Department | West Coast Metabolomics Center |
| Laboratory | Institut für Diabetesforschung und Metabolische Erkrankungen (IDM) |
| Last Name | Birkenfeld |
| First Name | Andreas |
| Address | Ottfried-Müller Str. 10 72076 Tübingen |
| Andreas.Birkenfeld@med.uni-tuebingen.de | |
| Phone | +49(0)7071 84 20257 |
| Submit Date | 2021-01-06 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | cdf |
| Analysis Type Detail | GC-MS |
| Release Date | 2021-04-01 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN002688 |
|---|---|
| Analysis type | MS |
| Chromatography type | GC |
| Chromatography system | Leco Pegasus IV |
| Column | Rtx-5Sil MS |
| MS Type | EI |
| MS instrument type | GC-TOF |
| MS instrument name | Leco Pegasus IV TOF |
| Ion Mode | UNSPECIFIED |
| Units | counts per second |
