Summary of Study ST002194

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001398. The data can be accessed directly via it's Project DOI: 10.21228/M8141Z This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  |  Perform analysis on untargeted data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST002194
Study TitleMetabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation
Study SummaryIn this study CE-MS and GC-MS based metabolomics was used to analyze COVID-19 disease. In total, 144 individuals classified as healthy, asymptomatic/mils, moderate and severe according to the highest COVID-19 severity status, were analyzed.
Last NameBarbas
First NameCoral
AddressCEU Universities, Urbanización Montepríncipe
Phone+34 913724700
Submit Date2022-06-09
Raw Data AvailableYes
Raw Data File Type(s)mzXML
Analysis Type DetailGC/LC-MS
Release Date2022-06-17
Release Version1
Coral Barbas Coral Barbas application/zip

Select appropriate tab below to view additional metadata details:

Combined analysis:

Analysis ID AN003591 AN003592
Analysis type MS MS
Chromatography type CE GC
Chromatography system Agilent 7100 CE 8890
Column silica capillary (100 cm; inner diameter,50um,Agilent Technologies) Agilent DB5-MS (30m x 0.25mm, 0.25um)
MS instrument type TOF Single quadrupole
MS instrument name Agilent CE-TOFMS Agilent 5977B
Units Peak Area Corrected areas


Chromatography ID:CH002653
Chromatography Summary:Metabolite separation was performed in a fused silica capillary (100 cm; inner diameter, 50 µm, Agilent Technologies). Before each analysis, background electrolyte (BFE) (0.8 M formic acid solution in 10 % MeOH; v/v) was flushed for 5 min (950 mbar). Samples injections were performed over 50 s at 50 mbar and BGE was injected after each injection for 10 s at 100 mbar to improve reproducibility. The separation was carried out with an internal pressure of 25 mbar and 30 kV voltage with a total analytical run time of 35 min.
Methods Filename:Sample_Analysis.pdf
Instrument Name:Agilent 7100 CE
Column Name:silica capillary (100 cm; inner diameter,50um,Agilent Technologies)
Chromatography Type:CE
Chromatography ID:CH002654
Chromatography Summary:The flow rate of helium carrier gas was constant at 1.1359 mL/min and the injector temperature was set at 250 °C. The lock of the retention time (RTL) relative to the internal standard (methyl stearate) peak at 19.66 min was performed. The oven temperature gradient was initially set at 60 °C and was maintained for 1 min. Then it was raised by 10 °C/min until it reached 325 °C, and then was held at this temperature for 10 min before cooling down. The total analysis run time was 37.5 min.
Methods Filename:Sample_Analysis.pdf
Instrument Name:8890
Column Name:Agilent DB5-MS (30m x 0.25mm, 0.25um)
Chromatography Type:GC