Summary of Study ST002314

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001484. The data can be accessed directly via it's Project DOI: 10.21228/M8WT54 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST002314
Study TitleDifferential requirements for mitochondrial electron transport chain components in the adult murine liver - Lactate/Pyruvate Tolerance Test
Study SummaryHepatic Cox10 knockout mice were injected with a lactate/pyruvate (10:1) solution with 40% of the mixture labeled with [U-13C]. After 30 minutes, plasma and liver tissue was harvested. Metabolites were extracted, dried, and derivatized to form methoxime-TBDMS adducts.
Institute
The University of Texas Southwestern Medical Center at Dallas
DepartmentChildren's Research Institute
LaboratoryPrashant Mishra
Last NameLesner
First NameNicholas
Address6000 Harry Hines BLVD
Emailnicholas.lesner@pennmedicine.upenn.edu
Phone2146483784
Submit Date2022-08-22
Num Groups2
Total Subjects9
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailGC-MS
Release Date2022-11-02
Release Version1
Nicholas Lesner Nicholas Lesner
https://dx.doi.org/10.21228/M8WT54
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:


Combined analysis:

Analysis ID AN003781
Analysis type MS
Chromatography type GC
Chromatography system Agilent 7890B
Column Agilent HP5-MS (30m x 0.25mm, 0.25 um)
MS Type EI
MS instrument type Single quadrupole
MS instrument name Agilent 5977A
Ion Mode POSITIVE
Units peak area

Chromatography:

Chromatography ID:CH002795
Chromatography Summary:60C for 1 min then 10C/min to 320C for 1 min 9 min at 320C
Instrument Name:Agilent 7890B
Column Name:Agilent HP5-MS (30m x 0.25mm, 0.25 um)
Injection Temperature:60
Internal Standard:Norvaline
Sample Injection:Splitless
Chromatography Type:GC
  logo