Summary of Study ST001385
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000949. The data can be accessed directly via it's Project DOI: 10.21228/M8198B This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001385 |
| Study Title | Microbial and metabolic variations mediate the influence of childhood and adolescent EDC and trace element exposure on breast density. |
| Study Summary | Our CHEAR project builds on the longitudinal Growth and Obesity Cohort Study in Santiago, Chile, which includes approximately 500 girls born in 2002-2003. Participants were recruited in 2006 from public nursery schools of six counties in Santiago representative of low to middle income families. Children were included if they were singletons with birthweight between 2500 and 4500g, and had no physical, medical or endocrine diseases that may alter the growth and/or onset of puberty. Semi-annual collection of participant anthropometric and pubertal development data by trained dietitians has continued since 2009. The overall objectives of our CHEAR study are to assess how exposure to endocrine-disrupting chemicals (phenols and phthalates), and trace elements (metals) measured in urine samples at Tanner stages 1 and 4 and 1 year post-menarche influence the pubertal microbiome and metabolome, and the potential impact on adolescent breast composition measured by DXA at Tanner stage 4 and 2 years post-menarche. |
| Institute | Icahn School of Medicine at Mount Sinai |
| Last Name | Petrick |
| First Name | Lauren |
| Address | Department of Environmental Medicine and Public Health, Atran Building 3rd floor, 101st St. between Madison and 5th Ave, New York, New York, 10029, USA |
| lauren.petrick@mssm.edu | |
| Phone | 212 241 7351 |
| Submit Date | 2020-05-22 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Chear Study | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-03-01 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Collection:
| Collection ID: | CO001454 |
| Collection Summary: | Samples were received and stored at -80°C until processing. In total, 315 samples had sufficient sample volume for metabolomics analysis. |
| Collection Protocol Filename: | Report_Michels__2017_1977.docx |
| Sample Type: | Urine |
| Storage Conditions: | -80℃ |
