Summary of Study ST001932

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001221. The data can be accessed directly via it's Project DOI: 10.21228/M8W682 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001932
Study TitlePerfluorinated compounds and high fat diet in relation to CVD-relevant metabolomic pathways in the SEARCH for Diabetes in Youth study
Study SummaryThis project aims to evaluate the association between environmental exposure to perfluorinated alkyl substances (PFCs) and the development of risk factors for cardiometabolic disease in youth diagnosed with diabetes in the SEARCH Cohort Study. The longitudinal study of newly diagnosed cases of type 1 and type 2 diabetes examines serum metabolome changes at baseline and follow-up at approximately 5 years (all >3 years from baseline). Exposures to PFCs and biological effects characterized by serum metabolome changes will be associated with known cardiometabolic risk factors in youth diagnosed with diabetes.
Emory University
DepartmentSchool of Medicine
LaboratoryClincal Biomarkers Laboratory
Last NameTran
First NameViLinh
Address615 Michael St, suite 225
Submit Date2021-10-06
Total Subjects1796
Study CommentsBoth CHEAR pooled plasma samples and Clinical Biomarker Laboratory pooled plasma samples were used
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Chear StudyYes
Analysis Type DetailLC-MS
Release Date2022-10-07
Release Version1
ViLinh Tran ViLinh Tran application/zip

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Collection ID:CO002003
Collection Summary:Blood serum samples were collected from participants in the SEARCH multi-center, longitudinal cohort study at baseline and >3 years from baseline. Serum was obtained from blood vein draw in children (<20 years of age) with incidence or clinical presentation of type 1 and type 2 diabetes. Blood samples were collected in red top vacutainer tubes and sit upright for 30 minutes for clot formation, followed by centrifugation and removal of 500ul aliquots of serum to 1.8ml freezer tubes and stored in a -70C freezer. The samples were shipped on dry ice from the clinical centers to the CHEAR URR at Emory University.
Sample Type:plasma
Storage Conditions:Described in summary