Summary of study ST000244

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000197. The data can be accessed directly via it's Project DOI: 10.21228/M8XK51 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000244
Study TitleMetabolomic Diagnosis in Horse
Study Typecomparison
Study SummaryIn this project we will investigate the feasibility of metabolomics and to characterize the diversity of “metabotypes” in the horse, towards discovery of markers and pathways associated with obesity and insulin resistance in the equine model. The collaborative team of researchers assembled for this work have identified horses severely affected with Equine Metabolic syndrome, often characterized by obesity and hyperinsulinemia. These animals are all from the Arabian breed, to control for some genetic background. Horses are age, sex and farm of residence matched with a control animal whenever possible. Carefully controlled collection protocols were utilized to ensure minimal variability in sample age and quality. Blood plasma is submitted for both global LC-MS analysis through the SECIM core facilities. This discovery-based approach will begin to generate new targets for the development of novel therapeutic interventions for the treatment and prevention of obesity, type-2 diabetes as well as related secondary conditions in both humans and horses. Finally, as the first dataset of its kind in the horse, we may also be able to highlight promising new biomarkers for veterinary diagnostic use.
Institute
University of Florida
Last NameBrooks
First NameSamantha
Emailsamantha.brooks@ufl.edu
Submit Date2015-10-13
Num Groups3
Total Subjects51
Raw Data AvailableYes
Raw Data File Type(s).raw
Analysis Type DetailLC-MS
Release Date2016-09-23
Release Version1
Samantha Brooks Samantha Brooks
https://dx.doi.org/10.21228/M8XK51
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Animal; Subject species: Equus caballus (Factor headings shown in green)

mb_sample_id local_sample_id Treatment Gender
SA0112652268Control Female
SA0112662227Control Female
SA0112672204Control Female
SA0112682223Control Female
SA0112692241Control Female
SA0112702232Control Female
SA0112712244Control Female
SA0112722267Control Female
SA0112732245Control Female
SA0112742214Control Female
SA0112752222Control Male(gelding)
SA0112762253Control Male(gelding)
SA0112772250Control Male(gelding)
SA0112782256Control Male(gelding)
SA0112792205Control Male(gelding)
SA0112802209Control Male(gelding)
SA0112812233Control Male(gelding)
SA0112952212EMS Female
SA0112962215EMS Female
SA0112972221EMS Female
SA0112982255EMS Female
SA0112992265EMS Female
SA0113002217EMS Female
SA0113012226EMS Female
SA0113022229EMS Female
SA0113032243EMS Female
SA0113042242EMS Female
SA0113052246EMS Female
SA0113062274EMS Female
SA0113072270EMS Male(gelding)
SA0113082266EMS Male(gelding)
SA0113092235EMS Male(gelding)
SA0113102228EMS Male(gelding)
SA0113112257EMS Male(gelding)
SA0113122247EMS Male(gelding)
SA0113132219EMS Male(gelding)
SA0113142239EMS Male(gelding)
SA0113152271EMS Male(gelding)
SA0112822254EMS-Treated Female
SA0112832220EMS-Treated Female
SA0112842263EMS-Treated Female
SA0112852258EMS-Treated Female
SA0112862216EMS-Treated Male(gelding)
SA0112872249EMS-Treated Male(gelding)
SA0112882210EMS-Treated Male(gelding)
SA0112892264EMS-Treated Male(gelding)
SA0112902238EMS-Treated Male(gelding)
SA0112912234EMS-Treated Male(gelding)
SA0112922225EMS-Treated Male(gelding)
SA0112932261EMS-Treated Male(gelding)
SA0112942248EMS-Treated Male(gelding)
Showing results 1 to 51 of 51
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