Summary of Study ST000337
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000269. The data can be accessed directly via it's Project DOI: 10.21228/M81307 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000337 |
Study Title | Metabolomics Approach to Allograft Assessment in Liver Transplantation |
Study Type | Retrospective analysis of biobanked liver tissue from organ donors |
Study Summary | This pilot study is designed to apply several types of metabolomic analysis for liver allograft assessment with the aim of identifying candidate biomarkers for allograft function and to develop a methodology that could be applied to larger scale studies. The three main categories of metabolomic analysis are reflected in each of the specific aims, including a targeted profiling of central carbon metabolism, open lipidomic and metabolomic profiling for hypothesis generation and MALDI-IMS for tissue-based spatial analysis. Each of these approaches offers potential benefits that could be optimized in a protocol for larger scale studies depending the results of the pilot investigations. |
Institute | Ochsner Multi-Organ Transplant Institute |
Department | SECIM |
Laboratory | Abdominal Organ Transplantation |
Last Name | Seal |
First Name | John |
Address | 1514 Jefferson Highway, New Orleans, LA 70121 |
John.Seal@ochsner.org | |
Phone | 504-232-4253 |
Submit Date | 2016-01-17 |
Num Groups | 3 |
Total Subjects | Targeted analysis and open profiling: Control group - standard criteria donor (N=15); Experimental group - donation-after-cardiac-death donors (N=10). MALDI-IMS - standard criteria donor (N=10) |
Raw Data File Type(s) | raw(Thermo), d |
Analysis Type Detail | LC-MS |
Release Date | 2017-01-17 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | DONOR CAUSE OF DEATH |
---|---|---|
SA015046 | 121089 | Anoxia |
SA015047 | 114291 | Anoxia |
SA015048 | 118601 | Anoxia |
SA015049 | 121079 | Anoxia |
SA015050 | 115347 | Anoxia |
SA015051 | 120257 | Anoxia |
SA015052 | 116736 | Anoxia |
SA015053 | 115165 | Anoxia |
SA015054 | 120237 | Anoxia |
SA015058 | 115333 | Cerebrovascular/Stroke |
SA015059 | 121063 | Cerebrovascular/Stroke |
SA015060 | 114647 | Cerebrovascular/Stroke |
SA015055 | 121364 | CVA |
SA015056 | 121358 | CVA |
SA015057 | 121356 | CVA |
SA015061 | 115342 | Trauma |
SA015062 | 116707 | Trauma |
SA015063 | 117751 | Trauma |
SA015064 | 114300 | Trauma |
SA015065 | 121095 | Trauma |
SA015066 | 121087 | Trauma |
SA015067 | 117323 | Trauma |
SA015068 | 120240 | Trauma |
SA015069 | 121091 | Trauma |
SA015070 | 116709 | Trauma |
Showing results 1 to 25 of 25 |