Summary of Study ST000445

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000343. The data can be accessed directly via it's Project DOI: 10.21228/M8JS49 This work is supported by NIH grant, U2C- DK119886.

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Study IDST000445
Study TitleFollicular fluid lipidomics reveals lipid alterations by LH addition during IVF cycles
Study SummaryPurpose Ovulation induction protocols are key components for performing assisted reproduction treatments successfully. The objective of the present study was to estimate how LH addition to controlled ovarian stimulation protocols may affect the follicular fluid lipid profile of women undergoing in vitro fertilization treatment. Methods We conducted the study using 28 self-paired samples, 14 per group. The patients received FSH during their first cycle of ovarian stimulation (FSH group). If treatment did not result in pregnancy, the same patients returned for a new cycle and received stimulus with the addition of LH to the previous protocol (Low-dose-LH group). Lipidomics analysis was performed by UPLC-MSE mass spectrometry. Potential lipid biomarkers were identified by the software Progenesis QI. Statistical analysis was performed using the SPSS 18.0 and MetaboAnalyst 2.0 software.
Institute
Universidade Federal de Sao Paulo
DepartmentSurgery
LaboratoryCentro de Pesquisa em Urologia
Last NameDa Costa
First NameLivia
AddressRua Embau 231 - Vila Clementino, Sao Paulo, Sao Paulo, 04039060, Brazil
Emailliviadovale@hotmail.com
Phone551138074062
Submit Date2016-07-25
Num Groups2
Total Subjects28
Num Females14
Study CommentsThe groups consists of the same 14 women submitted to two different controlled ovarian stimulation protocols (FSH or LH group)
Raw Data AvailableYes
Raw Data File Type(s)raw(Waters)
Analysis Type DetailLC-MS
Release Date2016-09-23
Release Version1
Livia Da Costa Livia Da Costa
https://dx.doi.org/10.21228/M8JS49
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human patients (Women); Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Treatment
SA022624UNIFESP_lip_LF12FSH
SA022625UNIFESP_lip_LF10FSH
SA022626UNIFESP_lip_LF13FSH
SA022627UNIFESP_lip_LF14FSH
SA022628UNIFESP_lip_LF1FSH
SA022629UNIFESP_lip_LF9FSH
SA022630UNIFESP_lip_LF11FSH
SA022631UNIFESP_lip_LF4FSH
SA022632UNIFESP_lip_LF8FSH
SA022633UNIFESP_lip_LF2FSH
SA022634UNIFESP_lip_LF5FSH
SA022635UNIFESP_lip_LF3FSH
SA022636UNIFESP_lip_LF6FSH
SA022637UNIFESP_lip_LF7FSH
SA022638UNIFESP_lip_LF25LH
SA022639UNIFESP_lip_LF24LH
SA022640UNIFESP_lip_LF26LH
SA022641UNIFESP_lip_LF28LH
SA022642UNIFESP_lip_LF23LH
SA022643UNIFESP_lip_LF27LH
SA022644UNIFESP_lip_LF15LH
SA022645UNIFESP_lip_LF17LH
SA022646UNIFESP_lip_LF16LH
SA022647UNIFESP_lip_LF18LH
SA022648UNIFESP_lip_LF19LH
SA022649UNIFESP_lip_LF21LH
SA022650UNIFESP_lip_LF20LH
SA022651UNIFESP_lip_LF22LH
Showing results 1 to 28 of 28
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