Summary of study ST001140

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000761. The data can be accessed directly via it's Project DOI: 10.21228/M89Q32 This work is supported by NIH grant, U2C- DK119886.


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Study IDST001140
Study TitleChanges in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure
Study SummaryGlucocorticoids (GCs) are widely used in veterinary and human medicine. Chromic endogenous or iatrogenic GC overexposure impairs metabolic function and can result in diverse side-effects, including Cushing’s syndrome. This study examines the effects of experimentally induced short-term and long-term GC excess (induced by prednisolone and tetracosactide, respectively) on the plasma lipidome of Beale dogs. Both, long- and short-term GC resulted in significant changes of the plasma lipidome.
National University of Singapore;University of Zurich
DepartmentSingapore Lipidomics Incubator (SLING);Vetsuisse Faculty, University of Zurich
LaboratorySingapore Lipidomics Incubator (SLING), National University of Singapore
Last NameBurla
First NameBo
Address28 Medical Drive, Singapore 117456, Singapore
Submit Date2019-01-19
Num Groups2
Total Subjects14
Num Males9
Num Females5
Raw Data AvailableYes
Raw Data File Type(s).d
Analysis Type DetailLC-MS
Release Date2019-03-06
Release Version1
Bo Burla Bo Burla application/zip

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Subject type: Mammal; Subject species: Canis lupus familiaris (Factor headings shown in green)

mb_sample_id local_sample_id TreatmentGroup TreatmentDuration SamplingTimePoint
SA078299Prednisolone-d0-P5Prednisolone 0d before
SA078300Prednisolone-d0-P6Prednisolone 0d before
SA078301Prednisolone-d0-P1Prednisolone 0d before
SA078302Prednisolone-d0-P4Prednisolone 0d before
SA078303Prednisolone-d0-P7Prednisolone 0d before
SA078304Prednisolone-d0-P8Prednisolone 0d before
SA078305Prednisolone-d0-P2Prednisolone 0d before
SA078306Prednisolone-d0-P3Prednisolone 0d before
SA078307Prednisolone-d4-P4Prednisolone 4d after
SA078308Prednisolone-d4-P1Prednisolone 4d after
SA078309Prednisolone-d4-P7Prednisolone 4d after
SA078310Prednisolone-d4-P8Prednisolone 4d after
SA078311Prednisolone-d4-P2Prednisolone 4d after
SA078312Prednisolone-d4-P3Prednisolone 4d after
SA078313Prednisolone-d4-P6Prednisolone 4d after
SA078314Prednisolone-d4-P5Prednisolone 4d after
SA078315Tetracosactide-w00-T6Tetracosactide 00w before
SA078316Tetracosactide-w00-T5Tetracosactide 00w before
SA078317Tetracosactide-w00-T4Tetracosactide 00w before
SA078318Tetracosactide-w00-T2Tetracosactide 00w before
SA078319Tetracosactide-w00-T1Tetracosactide 00w before
SA078320Tetracosactide-w00-T3Tetracosactide 00w before
SA078321Tetracosactide-w25-T5Tetracosactide 25w after
SA078322Tetracosactide-w25-T6Tetracosactide 25w after
SA078323Tetracosactide-w25-T1Tetracosactide 25w after
SA078324Tetracosactide-w25-T2Tetracosactide 25w after
SA078325Tetracosactide-w25-T3Tetracosactide 25w after
SA078326Tetracosactide-w25-T4Tetracosactide 25w after
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