Summary of Study ST001276

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000861. The data can be accessed directly via it's Project DOI: 10.21228/M8D392 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001276
Study TitleDevelopment and Characterisation of a Novel Class of Aroyl Guanidine Containing Anti-Trypanosomal Compounds
Study SummaryThe mode of action of a novel class of aroyl guanidine containing anti-Trypanosomal compounds was investigated using an unbiased metabolomics approach. Trypanosoma brucei parasites were incubated for five hours with the test compounds at 1 µM concentration. Analysis of cell pellets allowed reproducible detection of diverse metabolites from a range of metabolic pathways.
Institute
Monash University
Last NameCreek
First NameDarren
AddressMonash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Melbourne, Victoria, 3052, Australia
Emaildarren.creek@monash.edu
Phone+61 (0) 3 9903 9249
Submit Date2019-11-16
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2020-01-13
Release Version1
Darren Creek Darren Creek
https://dx.doi.org/10.21228/M8D392
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Trypanosoma brucei brucei (Factor headings shown in green)

mb_sample_id local_sample_id Drug treatment
SA093199P_DMSO_1DMSO
SA093200P_DMSO_2DMSO
SA093201P_DMSO_3DMSO
SA093202P_DMSO_4DMSO
SA093203P_112_2MIPS112
SA093204P_112_3MIPS112
SA093205P_112_4MIPS112
SA093206P_112_1MIPS112
SA093207P_116_3MIPS116
SA093208P_116_1MIPS116
SA093209P_116_2MIPS116
SA093210P_116_4MIPS116
SA093211P_12828_3MIPS12828
SA093212P_12828_2MIPS12828
SA093213P_12828_1MIPS12828
SA093214P_12828_4MIPS12828
SA093215P_14554_1MIPS14554
SA093216P_14554_4MIPS14554
SA093217P_14554_2MIPS14554
SA093218P_14554_3MIPS14554
SA093219P_15_3MIPS15
SA093220P_15_1MIPS15
SA093221P_15_2MIPS15
SA093222P_15_4MIPS15
SA093223P_8664_4MIPS8664
SA093224P_8664_1MIPS8664
SA093225P_8664_2MIPS8664
SA093226P_8664_3MIPS8664
SA093227P_9560_4MIPS9560
SA093228P_9560_1MIPS9560
SA093229P_9560_2MIPS9560
SA093230P_9560_3MIPS9560
SA093231P_9880_2MIPS9880
SA093232P_9880_1MIPS9880
SA093233P_9880_3MIPS9880
SA093234P_9880_4MIPS9880
Showing results 1 to 36 of 36
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