Summary of Study ST001303
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000884. The data can be accessed directly via it's Project DOI: 10.21228/M8DX2P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001303 |
Study Title | TGF-Beta 3 heterozygous mice |
Study Type | Mice nephropathy in lipotoxic model |
Study Summary | Transforming growth factor β (TGFβ) family comprises the main player in the development of fibrosis including three isoforms: TGFβ1, TGFβ2 and TGFβ3. TGFβ3 may play an antifibrotic role at the renal level, counteracting the role of TGFβ1, using a mouse model heterozygous for the TGFβ3 gene (TGFβ3+/-). Partial deletion of TGFβ3 causes in the mice albuminuria, loss of glomerular filtration rate, accelerated fibrosis, epithelial-to-mesenchymal transition and increment of glomerular basement membrane thickening. |
Institute | University Rey Juan Carlos |
Department | Basics Science of Health |
Last Name | Lanzon |
First Name | Borja |
Address | Avenida de Atenas S/N |
borja.lanzon@urjc.es | |
Phone | 663692554 |
Submit Date | 2019-12-19 |
Num Groups | 2 |
Total Subjects | 14 |
Num Males | 14 |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Analysis Type Detail | GC-MS/LC-MS |
Release Date | 2020-03-03 |
Release Version | 1 |
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Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
mb_sample_id | local_sample_id | Genotype |
---|---|---|
SA094330 | 98 HZCD | HZCD |
SA094331 | 269 HZCD | HZCD |
SA094332 | 127 HZCD | HZCD |
SA094333 | 25 HZCD | HZCD |
SA094334 | 119 HZCD | HZCD |
SA094335 | 130 HZCD | HZCD |
SA094336 | 267 HZCD | HZCD |
SA094337 | QC2 | QC |
SA094338 | QC3 | QC |
SA094339 | QC5 | QC |
SA094340 | QC1 | QC |
SA094341 | QC4 | QC |
SA094342 | 120 WTCD | WTCD |
SA094343 | 251 WTCD | WTCD |
SA094344 | 132 WTCD | WTCD |
SA094345 | 79 WTCD | WTCD |
SA094346 | 129 WTCD | WTCD |
SA094347 | 128 WTCD | WTCD |
SA094348 | 92 WTCD | WTCD |
Showing results 1 to 19 of 19 |