Summary of Study ST001323

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000900. The data can be accessed directly via it's Project DOI: 10.21228/M8BX09 This work is supported by NIH grant, U2C- DK119886.


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Study IDST001323
Study TitleEffect of high-fat diet on serum lipidome in mice
Study SummaryWe analyzed mouse serum samples from a mouse dietary intervention experiment. Briefly, C57BL/6 mice (n=44) were divided into 4 groups (n=11 per group) and fed High-fat diet (HFD), 1% deoxycholic acid (DCA) in drinking water, both, or left as control for 9 months. For quality control, 12 TQC samples and 2 blanks were also included in the analysis (total 58 samples and 6 groups). The two treatments were selected to demonstrate the ability of lipidomics to detect gross changes induced by HFD in the serum lipidome, as well as specific/minor changes induced by the secondary bile acid (DCA) through regulation of liver lipid metabolism.
QIMR Berghofer Medical Research Institute
Last NameMohamed
First NameAhmed
Address300 Herston Road
Submit Date2020-03-02
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2020-03-20
Release Version1
Ahmed Mohamed Ahmed Mohamed application/zip

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Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Diet BileAcid
SA096024Blank_1blank blank
SA096025Blank_2blank blank
SA095968S5DHighFat DCA
SA095969S4DHighFat DCA
SA095970S1DHighFat DCA
SA095971S6DHighFat DCA
SA095972S2DHighFat DCA
SA095973S3DHighFat DCA
SA095974S7DHighFat DCA
SA095975S11DHighFat DCA
SA095976S10DHighFat DCA
SA095977S9DHighFat DCA
SA095978S8DHighFat DCA
SA095979S4CHighFat water
SA095980S5CHighFat water
SA095981S3CHighFat water
SA095982S6CHighFat water
SA095983S2CHighFat water
SA095984S10CHighFat water
SA095985S1CHighFat water
SA095986S11CHighFat water
SA095987S9CHighFat water
SA095988S7CHighFat water
SA095989S8CHighFat water
SA095990S3BNormal DCA
SA095991S2BNormal DCA
SA095992S1BNormal DCA
SA095993S11BNormal DCA
SA095994S4BNormal DCA
SA095995S5BNormal DCA
SA095996S9BNormal DCA
SA095997S10BNormal DCA
SA095998S7BNormal DCA
SA095999S8BNormal DCA
SA096000S6BNormal DCA
SA096001S7ANormal water
SA096002S5ANormal water
SA096003S3ANormal water
SA096004S2ANormal water
SA096005S4ANormal water
SA096006S6ANormal water
SA096007S8ANormal water
SA096008S1ANormal water
SA096009S11ANormal water
SA096010S9ANormal water
SA096011S10ANormal water
SA096012TQC_9QC QC
SA096013TQC_8QC QC
SA096014TQC_12QC QC
SA096015TQC_7QC QC
SA096016TQC_11QC QC
SA096017TQC_10QC QC
SA096018TQC_4QC QC
SA096019TQC_1QC QC
SA096020TQC_6QC QC
SA096021TQC_2QC QC
SA096022TQC_3QC QC
SA096023TQC_5QC QC
Showing results 1 to 58 of 58