Summary of Study ST002127

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001348. The data can be accessed directly via it's Project DOI: 10.21228/M8GD8D This work is supported by NIH grant, U2C- DK119886.

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This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002127
Study TitleAmino acids and TCA substrates in hematopoietic cells (Part4)
Study SummaryThis study uses [13C,15N] labeled amino acids to study the amino acid consumption and their catabolism into tricarboxylic acid cycle substrates in hematopoietic stem cells, hemopoietic progenitors, and differentiated hematopoietic cells under different conditions, such as homeostasis and proliferation and with drug treatment.
Institute
Sun Yat-sen University
Last NameZhao
First NameMeng
AddressZhongshan 2nd Road
Emailzhaom38@mail.sysu.edu.cn
Phone18138799889
Submit Date2022-04-06
Raw Data AvailableYes
Raw Data File Type(s)cdf
Analysis Type DetailGC-MS
Release Date2022-11-01
Release Version1
Meng Zhao Meng Zhao
https://dx.doi.org/10.21228/M8GD8D
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Source_Name[gating] Treatment Batch Note
SA204401HSC_sot_ND_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 1 h 1e [13C, 15N]AAs were used for AA uptake (FigS6.J)
SA204402HSC_sot_ND_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 1 h 1e [13C, 15N]AAs were used for AA uptake (FigS6.J)
SA204403HSC_sot_ND_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 1 h 1e [13C, 15N]AAs were used for AA uptake (FigS6.J)
SA204392HSC_sot_ND_0h_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204393HSC_sot_ND_0h_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204394HSC_sot_ND_0h_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204395HSC_sot_ND_12h_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204396HSC_sot_ND_12h_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204397HSC_sot_ND_12h_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204398HSC_sot_ND_6h_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204399HSC_sot_ND_6h_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204400HSC_sot_ND_6h_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) Ctrl, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204404HSC_sot_NR_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 1 h 1e [13C, 15N]AAs were used for AA uptake (FigS6.J)
SA204405HSC_sot_NR_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 1 h 1e [13C, 15N]AAs were used for AA uptake (FigS6.J)
SA204406HSC_sot_NR_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 1 h 1e [13C, 15N]AAs were used for AA uptake (FigS6.J)
SA204407HSC_sot_NR_0h_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204408HSC_sot_NR_0h_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204409HSC_sot_NR_0h_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 0 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204410HSC_sot_NR_12h_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204411HSC_sot_NR_12h_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204412HSC_sot_NR_12h_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 12 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204413HSC_sot_NR_6h_2Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204414HSC_sot_NR_6h_3Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
SA204415HSC_sot_NR_6h_1Lin– Scal1+ c-Kit+ CD48– CD150+ (HSC) NR 1 week, [13C, 15N] AAs were incorporated for 24 h and subsequently washed out for 6 h 1e [13C, 15N] AA levels and [13C]TCA substrate levels in different time point were calculated for AA catabolism (Fig5.L).
Showing results 1 to 24 of 24
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