Summary of Study ST003297
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002048. The data can be accessed directly via it's Project DOI: 10.21228/M8WG0S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST003297 |
| Study Title | Metabolomic profiling of cultured TRAMP-C2 cells in the presence or absence of PD-L1. |
| Study Summary | Recent evidence suggests that PD-L1, well-known as the ligand of the immune inhibitory receptor PD-1, can have cell-intrinsic effects in cancer and immune cells. One such cell-intrinsic effect is modulation of cellular metabolism, including regulation of mTOR activity and glycolysis. Here, we analyzed the metabolome of cultured mouse prostate cancer cells (TRAMP-C2) expressing PD-L1 or with PD-L1 deleted via CRISPR/Cas9. |
| Institute | University of Ottawa |
| Last Name | Hodgins |
| First Name | Jonathan |
| Address | 451 Smyth Rd, Ottawa, ON K1H 8M5, Canada |
| jonathanhodgins17@gmail.com | |
| Phone | 613-562-5800 |
| Submit Date | 2024-05-21 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-07-28 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Cultured cells; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Sample source | Genotype |
|---|---|---|---|
| SA357986 | 2021-11-22 KO_Lys_1in100_06 | Cell lysate | PD-L1 KO |
| SA357987 | 2021-11-22 KO_Lys_1in10_02 | Cell lysate | PD-L1 KO |
| SA357988 | 2021-11-22 KO_Lys_UnDiluted_06 | Cell lysate | PD-L1 KO |
| SA357989 | 2021-11-22 KO_Lys_UnDiluted_05 | Cell lysate | PD-L1 KO |
| SA357990 | 2021-11-22 KO_Lys_UnDiluted_04 | Cell lysate | PD-L1 KO |
| SA357991 | 2021-11-22 KO_Lys_UnDiluted_03 | Cell lysate | PD-L1 KO |
| SA357992 | 2021-11-22 KO_Lys_UnDiluted_02 | Cell lysate | PD-L1 KO |
| SA357993 | 2021-11-22 KO_Lys_UnDiluted_01 | Cell lysate | PD-L1 KO |
| SA357994 | 2021-11-22 KO_Lys_1in10_01 | Cell lysate | PD-L1 KO |
| SA357995 | 2021-11-22 KO_Lys_1in100_05 | Cell lysate | PD-L1 KO |
| SA357996 | 2021-11-22 KO_Lys_1in10_05 | Cell lysate | PD-L1 KO |
| SA357997 | 2021-11-22 KO_Lys_1in10_03 | Cell lysate | PD-L1 KO |
| SA357998 | 2021-11-22 KO_Lys_1in10_04 | Cell lysate | PD-L1 KO |
| SA357999 | 2021-11-22 KO_Lys_1in100_04 | Cell lysate | PD-L1 KO |
| SA358000 | 2021-11-22 KO_Lys_1in10_06 | Cell lysate | PD-L1 KO |
| SA358001 | 2021-11-22 KO_Lys_1in100_01 | Cell lysate | PD-L1 KO |
| SA358002 | 2021-11-22 KO_Lys_1in100_02 | Cell lysate | PD-L1 KO |
| SA358003 | 2021-11-22 KO_Lys_1in100_03 | Cell lysate | PD-L1 KO |
| SA358004 | 2021-11-22 WT_Lys_1in100_05 | Cell lysate | Wild-type |
| SA358005 | 2021-11-22 WT_Lys_UnDiluted_06 | Cell lysate | Wild-type |
| SA358006 | 2021-11-22 WT_Lys_UnDiluted_05 | Cell lysate | Wild-type |
| SA358007 | 2021-11-22 WT_Lys_UnDiluted_04 | Cell lysate | Wild-type |
| SA358008 | 2021-11-22 WT_Lys_UnDiluted_03 | Cell lysate | Wild-type |
| SA358009 | 2021-11-22 WT_Lys_UnDiluted_02 | Cell lysate | Wild-type |
| SA358010 | 2021-11-22 WT_Lys_UnDiluted_01 | Cell lysate | Wild-type |
| SA358011 | 2021-11-22 WT_Lys_1in100_06 | Cell lysate | Wild-type |
| SA358012 | 2021-11-22 WT_Lys_1in100_04 | Cell lysate | Wild-type |
| SA358013 | 2021-11-22 WT_Lys_1in100_02 | Cell lysate | Wild-type |
| SA358014 | 2021-11-22 WT_Lys_1in100_01 | Cell lysate | Wild-type |
| SA358015 | 2021-11-22 WT_Lys_1in10_06 | Cell lysate | Wild-type |
| SA358016 | 2021-11-22 WT_Lys_1in10_05 | Cell lysate | Wild-type |
| SA358017 | 2021-11-22 WT_Lys_1in10_04 | Cell lysate | Wild-type |
| SA358018 | 2021-11-22 WT_Lys_1in10_03 | Cell lysate | Wild-type |
| SA358019 | 2021-11-22 WT_Lys_1in100_03 | Cell lysate | Wild-type |
| SA358020 | 2021-11-22 WT_Lys_1in10_01 | Cell lysate | Wild-type |
| SA358021 | 2021-11-22 WT_Lys_1in10_02 | Cell lysate | Wild-type |
| SA358022 | 2021-11-18 KO_Media_1in100_05 | Conditioned media | PD-L1 KO |
| SA358023 | 2021-11-24 KO_CM_UnDiluted_02 | Conditioned media | PD-L1 KO |
| SA358024 | 2021-11-24 KO_CM_UnDiluted_01 | Conditioned media | PD-L1 KO |
| SA358025 | 2021-11-24 KO_CM_UnDiluted_06 | Conditioned media | PD-L1 KO |
| SA358026 | 2021-11-24 KO_CM_UnDiluted_03 | Conditioned media | PD-L1 KO |
| SA358027 | 2021-11-24 KO_CM_UnDiluted_04 | Conditioned media | PD-L1 KO |
| SA358028 | 2021-11-24 KO_CM_UnDiluted_05 | Conditioned media | PD-L1 KO |
| SA358029 | 2021-11-18 KO_Media_1in100_06 | Conditioned media | PD-L1 KO |
| SA358030 | 2021-11-18 KO_Media_1in100_02 | Conditioned media | PD-L1 KO |
| SA358031 | 2021-11-18 KO_Media_1in100_04 | Conditioned media | PD-L1 KO |
| SA358032 | 2021-11-18 KO_Media_1in100_01 | Conditioned media | PD-L1 KO |
| SA358033 | 2021-11-18 KO_Media_1in10_01 | Conditioned media | PD-L1 KO |
| SA358034 | 2021-11-18 KO_Media_1in10_02 | Conditioned media | PD-L1 KO |
| SA358035 | 2021-11-18 KO_Media_1in10_04 | Conditioned media | PD-L1 KO |
| SA358036 | 2021-11-18 KO_Media_1in10_05 | Conditioned media | PD-L1 KO |
| SA358037 | 2021-11-18 KO_Media_1in100_03 | Conditioned media | PD-L1 KO |
| SA358038 | 2021-11-18 KO_Media_1in10_06 | Conditioned media | PD-L1 KO |
| SA358039 | 2021-11-18 KO_Media_1in10_03 | Conditioned media | PD-L1 KO |
| SA358040 | 2021-11-18 WT_Media_1in10_02 | Conditioned media | Wild-type |
| SA358041 | 2021-11-24 WT_CM_UnDiluted_06 | Conditioned media | Wild-type |
| SA358042 | 2021-11-24 WT_CM_UnDiluted_05 | Conditioned media | Wild-type |
| SA358043 | 2021-11-24 WT_CM_UnDiluted_04 | Conditioned media | Wild-type |
| SA358044 | 2021-11-24 WT_CM_UnDiluted_03 | Conditioned media | Wild-type |
| SA358045 | 2021-11-24 WT_CM_UnDiluted_02 | Conditioned media | Wild-type |
| SA358046 | 2021-11-24 WT_CM_UnDiluted_01 | Conditioned media | Wild-type |
| SA358047 | 2021-11-18 WT_Media_1in100_02 | Conditioned media | Wild-type |
| SA358048 | 2021-11-18 WT_Media_1in100_01 | Conditioned media | Wild-type |
| SA358049 | 2021-11-18 WT_Media_1in10_03 | Conditioned media | Wild-type |
| SA358050 | 2021-11-18 WT_Media_1in10_04 | Conditioned media | Wild-type |
| SA358051 | 2021-11-18 WT_Media_1in10_05 | Conditioned media | Wild-type |
| SA358052 | 2021-11-18 WT_Media_1in10_06 | Conditioned media | Wild-type |
| SA358053 | 2021-11-18 WT_Media_1in100_06 | Conditioned media | Wild-type |
| SA358054 | 2021-11-18 WT_Media_1in100_05 | Conditioned media | Wild-type |
| SA358055 | 2021-11-18 WT_Media_1in100_04 | Conditioned media | Wild-type |
| SA358056 | 2021-11-18 WT_Media_1in100_03 | Conditioned media | Wild-type |
| SA358057 | 2021-11-18 WT_Media_1in10_01 | Conditioned media | Wild-type |
| SA358058 | 2021-11-18 MediaOnly_1in10 | Culture media | N/A |
| SA358059 | 2021-11-18 MediaOnly_1in100. | Culture media | N/A |
| SA358060 | 2021-11-24 Media Only_UnDiluted | Culture media | N/A |
| Showing results 1 to 75 of 75 |
