Summary of Study ST003429

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001941. The data can be accessed directly via it's Project DOI: 10.21228/M8TM76 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003429
Study TitleIntracellular and medium metabolomics of BT-474 cells treated with Fasnall that was manufactured by Enamine
Study SummaryBT-474 human breast cancer cells were treated with various concentrations of Fasnall for 24 h. The drug was manufactured by Enamine (1-benzyl-N-{5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}pyrrolidin-3-amine, EN300-14327544).
Institute
Wistar Institute
DepartmentMolecular and Cellular Oncogenesis Program, Ellen and Ronald Caplan Cancer Center
LaboratorySchug's Lab
Last NameMukha
First NameDzmitry
Address3601 Spruce St, Philadelphia, PA 19104, USA
Emaildmukha@wistar.org
Phone+12154956903
Submit Date2024-08-21
Num Groups15
Total Subjects45
PublicationsSubmission Pending
Raw Data AvailableYes
Raw Data File Type(s)mzML, wiff
Analysis Type DetailLC-MS
Release Date2024-09-12
Release Version1
Dzmitry Mukha Dzmitry Mukha
https://dx.doi.org/10.21228/M8TM76
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Sample source Sample Type Drug Treatment
SA37782211 BT-474 Fasnall 0.1 uM cellsBT-474 breast cancer cells Intracellular 0.1 uM Fasnall
SA37782304 BT-474 Fasnall 0.1 uM cellsBT-474 breast cancer cells Intracellular 0.1 uM Fasnall
SA37782418 BT-474 Fasnall 0.1 uM cellsBT-474 breast cancer cells Intracellular 0.1 uM Fasnall
SA37782821 BT-474 Fasnall 10 uM cellsBT-474 breast cancer cells Intracellular 10 uM Fasnall
SA37782914 BT-474 Fasnall 10 uM cellsBT-474 breast cancer cells Intracellular 10 uM Fasnall
SA37783007 BT-474 Fasnall 10 uM cellsBT-474 breast cancer cells Intracellular 10 uM Fasnall
SA37782505 BT-474 Fasnall 1 uM cellsBT-474 breast cancer cells Intracellular 1 uM Fasnall
SA37782619 BT-474 Fasnall 1 uM cellsBT-474 breast cancer cells Intracellular 1 uM Fasnall
SA37782712 BT-474 Fasnall 1 uM cellsBT-474 breast cancer cells Intracellular 1 uM Fasnall
SA37783108 BT-474 Fasnall 20 uM cellsBT-474 breast cancer cells Intracellular 20 uM Fasnall
SA37783215 BT-474 Fasnall 20 uM cellsBT-474 breast cancer cells Intracellular 20 uM Fasnall
SA37783322 BT-474 Fasnall 20 uM cellsBT-474 breast cancer cells Intracellular 20 uM Fasnall
SA37783423 BT-474 Fasnall 40 uM cellsBT-474 breast cancer cells Intracellular 40 uM Fasnall
SA37783516 BT-474 Fasnall 40 uM cellsBT-474 breast cancer cells Intracellular 40 uM Fasnall
SA37783609 BT-474 Fasnall 40 uM cellsBT-474 breast cancer cells Intracellular 40 uM Fasnall
SA37783706 BT-474 Fasnall 5 uM cellsBT-474 breast cancer cells Intracellular 5 uM Fasnall
SA37783820 BT-474 Fasnall 5 uM cellsBT-474 breast cancer cells Intracellular 5 uM Fasnall
SA37783913 BT-474 Fasnall 5 uM cellsBT-474 breast cancer cells Intracellular 5 uM Fasnall
SA37784010 BT-474 Fasnall 0 uM cellsBT-474 breast cancer cells Intracellular Control
SA37784103 BT-474 Fasnall 0 uM cellsBT-474 breast cancer cells Intracellular Control
SA37784217 BT-474 Fasnall 0 uM cellsBT-474 breast cancer cells Intracellular Control
SA37784333 BT-474 Fasnall 0.1 uM medBT-474 breast cancer cells Medium 0.1 uM Fasnall
SA37784425 BT-474 Fasnall 0.1 uM medBT-474 breast cancer cells Medium 0.1 uM Fasnall
SA37784541 BT-474 Fasnall 0.1 uM medBT-474 breast cancer cells Medium 0.1 uM Fasnall
SA37784929 BT-474 Fasnall 10 uM medBT-474 breast cancer cells Medium 10 uM Fasnall
SA37785045 BT-474 Fasnall 10 uM medBT-474 breast cancer cells Medium 10 uM Fasnall
SA37785137 BT-474 Fasnall 10 uM medBT-474 breast cancer cells Medium 10 uM Fasnall
SA37784642 BT-474 Fasnall 1 uM medBT-474 breast cancer cells Medium 1 uM Fasnall
SA37784734 BT-474 Fasnall 1 uM medBT-474 breast cancer cells Medium 1 uM Fasnall
SA37784826 BT-474 Fasnall 1 uM medBT-474 breast cancer cells Medium 1 uM Fasnall
SA37785246 BT-474 Fasnall 20 uM medBT-474 breast cancer cells Medium 20 uM Fasnall
SA37785338 BT-474 Fasnall 20 uM medBT-474 breast cancer cells Medium 20 uM Fasnall
SA37785430 BT-474 Fasnall 20 uM medBT-474 breast cancer cells Medium 20 uM Fasnall
SA37785531 BT-474 Fasnall 40 uM medBT-474 breast cancer cells Medium 40 uM Fasnall
SA37785647 BT-474 Fasnall 40 uM medBT-474 breast cancer cells Medium 40 uM Fasnall
SA37785739 BT-474 Fasnall 40 uM medBT-474 breast cancer cells Medium 40 uM Fasnall
SA37785843 BT-474 Fasnall 5 uM medBT-474 breast cancer cells Medium 5 uM Fasnall
SA37785927 BT-474 Fasnall 5 uM medBT-474 breast cancer cells Medium 5 uM Fasnall
SA37786035 BT-474 Fasnall 5 uM medBT-474 breast cancer cells Medium 5 uM Fasnall
SA37786140 BT-474 Fasnall 0 uM medBT-474 breast cancer cells Medium Control
SA37786224 BT-474 Fasnall 0 uM medBT-474 breast cancer cells Medium Control
SA37786332 BT-474 Fasnall 0 uM medBT-474 breast cancer cells Medium Control
SA37786449 BlankNA Blank NA
SA37786501 BlankNA Blank NA
SA37786644 Bottle mediumNA Medium 10 uM Fasnall
SA37786736 Bottle mediumNA Medium 10 uM Fasnall
SA37786828 Bottle mediumNA Medium 10 uM Fasnall
SA37786902 DMEM/F12 no addsNA QC NA
SA37787048 DMEM/F12 no addsNA QC NA
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