Summary of Study ST003484

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002140. The data can be accessed directly via it's Project DOI: 10.21228/M80R74 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003484
Study TitleMetabolism of TNBC cell line MDA-MB-453 is altered by cytokines, TDO2 inhibition, or suspension growth conditions - cellular steady state metabolome and in vitro tracing with 13C11 tryptophan
Study SummaryTNBC cell line MDA-MB-453 was cultured in 13C11 tryptophan and experimental treatments were as follows: a) cytokine treatment (TNFα+IL1β); b) treated with TDO2/IDO1 dual inhibitor AT-0174 for 24 or 48 hours with an without labeled tryptophan; c) cultured in 13C11 tryptophan and suspension condition.
Institute
University of Colorado Anschutz Medical Campus
Last NameHaines
First NameJulie
Address12801 E 17th Ave, Room 1303, Aurora, Colorado, 80045, USA
Emailjulie.haines@cuanschutz.edu
Phone3037243339
Submit Date2024-09-16
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2024-10-03
Release Version1
Julie Haines Julie Haines
https://dx.doi.org/10.21228/M80R74
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Growth condition time (h) treatment Sample source
SA383874MA0-2Attached 0 none Breast cancer cells
SA383875MA0-1Attached 0 none Breast cancer cells
SA383876MA0-3Attached 0 none Breast cancer cells
SA383877MA610-24-3Attached 24 10µM 68c091 Breast cancer cells
SA383878MA610-24-2Attached 24 10µM 68c091 Breast cancer cells
SA383879MA610-24-1Attached 24 10µM 68c091 Breast cancer cells
SA383880MAA10-24-2Attached 24 10µM AT0174 Breast cancer cells
SA383881MAA10-24-3Attached 24 10µM AT0174 Breast cancer cells
SA383882MAA10-24-1Attached 24 10µM AT0174 Breast cancer cells
SA383883MAA1-24-2Attached 24 1µM AT0174 Breast cancer cells
SA383884MAA1-24-1Attached 24 1µM AT0174 Breast cancer cells
SA383885MAA1-24-3Attached 24 1µM AT0174 Breast cancer cells
SA383886MAD-24-1Attached 24 DMSO Breast cancer cells
SA383887MAD-24-3Attached 24 DMSO Breast cancer cells
SA383888MAD-24-2Attached 24 DMSO Breast cancer cells
SA383889MAT-24-1Attached 24 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383890MAT-24-2Attached 24 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383891MAT-24-3Attached 24 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383892MAV-24-1Attached 24 Vehicle Breast cancer cells
SA383893MAV-24-2Attached 24 Vehicle Breast cancer cells
SA383894MAV-24-3Attached 24 Vehicle Breast cancer cells
SA383895MA610-48-1Attached 48 10µM 68c091 Breast cancer cells
SA383896MA610-48-2Attached 48 10µM 68c091 Breast cancer cells
SA383897MA610-48-3Attached 48 10µM 68c091 Breast cancer cells
SA383898MAA10-48-2Attached 48 10µM AT0174 Breast cancer cells
SA383899MAA10-48-1Attached 48 10µM AT0174 Breast cancer cells
SA383900MAA10-48-3Attached 48 10µM AT0174 Breast cancer cells
SA383901MAA1-48-2Attached 48 1µM AT0174 Breast cancer cells
SA383902MAA1-48-1Attached 48 1µM AT0174 Breast cancer cells
SA383903MAA1-48-3Attached 48 1µM AT0174 Breast cancer cells
SA383904MAD-48-3Attached 48 DMSO Breast cancer cells
SA383905MAD-48-2Attached 48 DMSO Breast cancer cells
SA383906MAD-48-1Attached 48 DMSO Breast cancer cells
SA383907MAT-48-1Attached 48 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383908MAT-48-2Attached 48 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383909MAT-48-3Attached 48 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383913MA48-3Attached 48 none Breast cancer cells
SA383914MA48-1Attached 48 none Breast cancer cells
SA383915MA48-2Attached 48 none Breast cancer cells
SA383910MAV-48-1Attached 48 Vehicle Breast cancer cells
SA383911MAV-48-2Attached 48 Vehicle Breast cancer cells
SA383912MAV-48-3Attached 48 Vehicle Breast cancer cells
SA383916MA72-3Attached 72 none Breast cancer cells
SA383917MA72-2Attached 72 none Breast cancer cells
SA383918MA72-1Attached 72 none Breast cancer cells
SA383919MS0-3Suspension 0 none Breast cancer cells
SA383920MS0-1Suspension 0 none Breast cancer cells
SA383921MS0-2Suspension 0 none Breast cancer cells
SA383922MS610-24-1Suspension 24 10µM 68c091 Breast cancer cells
SA383923MS610-24-2Suspension 24 10µM 68c091 Breast cancer cells
SA383924MS610-24-3Suspension 24 10µM 68c091 Breast cancer cells
SA383925MSA10-24-2Suspension 24 10µM AT0174 Breast cancer cells
SA383926MSA10-24-3Suspension 24 10µM AT0174 Breast cancer cells
SA383927MSA10-24-1Suspension 24 10µM AT0174 Breast cancer cells
SA383928MSA1-24-2Suspension 24 1µM AT0174 Breast cancer cells
SA383929MSA1-24-3Suspension 24 1µM AT0174 Breast cancer cells
SA383930MSA1-24-1Suspension 24 1µM AT0174 Breast cancer cells
SA383931MSD-24-3Suspension 24 DMSO Breast cancer cells
SA383932MSD-24-1Suspension 24 DMSO Breast cancer cells
SA383933MSD-24-2Suspension 24 DMSO Breast cancer cells
SA383934MST-24-3Suspension 24 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383935MST-24-1Suspension 24 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383936MST-24-2Suspension 24 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383937MSV-24-2Suspension 24 Vehicle Breast cancer cells
SA383938MSV-24-3Suspension 24 Vehicle Breast cancer cells
SA383939MSV-24-1Suspension 24 Vehicle Breast cancer cells
SA383940MS610-48-2Suspension 48 10µM 68c091 Breast cancer cells
SA383941MS610-48-1Suspension 48 10µM 68c091 Breast cancer cells
SA383942MS610-48-3Suspension 48 10µM 68c091 Breast cancer cells
SA383943MSA10-48-3Suspension 48 10µM AT0174 Breast cancer cells
SA383944MSA10-48-1Suspension 48 10µM AT0174 Breast cancer cells
SA383945MSA10-48-2Suspension 48 10µM AT0174 Breast cancer cells
SA383946MSA1-48-3Suspension 48 1µM AT0174 Breast cancer cells
SA383947MSA1-48-2Suspension 48 1µM AT0174 Breast cancer cells
SA383948MSA1-48-1Suspension 48 1µM AT0174 Breast cancer cells
SA383949MSD-48-3Suspension 48 DMSO Breast cancer cells
SA383950MSD-48-2Suspension 48 DMSO Breast cancer cells
SA383951MSD-48-1Suspension 48 DMSO Breast cancer cells
SA383952MST-48-2Suspension 48 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383953MST-48-3Suspension 48 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383954MST-48-1Suspension 48 NFkB cocktail 10 ng/ml IL1b + 10 ng/ml TNFa Breast cancer cells
SA383958MS48-1Suspension 48 none Breast cancer cells
SA383959MS48-2Suspension 48 none Breast cancer cells
SA383960MS48-3Suspension 48 none Breast cancer cells
SA383955MSV-48-3Suspension 48 Vehicle Breast cancer cells
SA383956MSV-48-2Suspension 48 Vehicle Breast cancer cells
SA383957MSV-48-1Suspension 48 Vehicle Breast cancer cells
SA383961MS72-1Suspension 72 none Breast cancer cells
SA383962MS72-2Suspension 72 none Breast cancer cells
SA383963MS72-3Suspension 72 none Breast cancer cells
Showing results 1 to 90 of 90
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