Summary of Study ST001176

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000788. The data can be accessed directly via it's Project DOI: 10.21228/M8TM3P This work is supported by NIH grant, U2C- DK119886.

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Study IDST001176
Study TitleMetabolite changes in human plasma before and after YF17D vaccination in symptomatic and asymptomatic subjects
Study SummaryPlasma was taken before and 1 day post-YF17D vaccination in a total of 13 subjects, of which 6 were asymptomatic and 7 were symptomatic.
Institute
Duke-NUS Medical School
Last NameChan
First NameKuan Rong
Address8 College Road Singapore 169857, Singapore, Singapore, 169857, Singapore
Emailkuanrong.chan@duke-nus.edu.sg
Phone90058277
Submit Date2019-04-25
Num Groups2
Total Subjects13
Raw Data AvailableYes
Analysis Type DetailCE-MS
Release Date2019-05-15
Release Version1
Kuan Rong Chan Kuan Rong Chan
https://dx.doi.org/10.21228/M8TM3P
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN001952
Analysis type MS
Chromatography type CE
Chromatography system Agilent 6210
Column Agilent capillary electrophoresis system
MS Type ESI
MS instrument type CE-TOFMS
MS instrument name Agilent 6210 TOF
Ion Mode UNSPECIFIED
Units uM

MS:

MS ID:MS001807
Analysis ID:AN001952
Instrument Name:Agilent 6210 TOF
Instrument Type:CE-TOFMS
MS Type:ESI
MS Comments:The spectrometer was scanned from m/z 50 to 1,000. Peaks were extracted using MasterHands, automatic integration software (Keio University, Tsuruoka, Yamagata, Japan) in order to obtain peak information including m/z, peak area, and migration time (MT)43. Signal peaks corresponding to isotopomers, adduct ions, and other product ions of known metabolites were excluded, and remaining peaks were annotated according to the HMT metabolite database based on their m/z values with the MTs. Areas of the annotated peaks were then normalized based on internal standard levels and sample volumes in order to obtain relative levels of each metabolite. Partial least square discriminant analysis was performed by HMT’s proprietary software, PeakStat and SampleStat, respectively. Pathway analysis is performed by MetaboAnalyst 4.0.
Ion Mode:UNSPECIFIED
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