Summary of Study ST001324

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000901. The data can be accessed directly via it's Project DOI: 10.21228/M8770G This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001324
Study TitleMetabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress
Study SummaryWe compared two groups of abalones (from the same population) with different temperature acclimation history, through their survival at acute heat treatment and metabolites changes. The results indicated significantly higher survival for the high temperature acclimation group. Both groups experienced mitochondrial homeostasis break down during heat treatment, while the higher temperature acclimation group accumulated more metabolites beneficial to metabolic homeostasis, including various dipeptides, antioxidants, and neuroprotective substances.
Institute
Institute of Oceanology, Chinese Academy of Sciences
Last NameXu
First NameFei
Address7 Nanhai Road, Qingdao, Shandong, 266071, China
Emailxufei@qdio.ac.cn
Phone+86-13791940813
Submit Date2020-01-30
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2020-09-10
Release Version1
Fei Xu Fei Xu
https://dx.doi.org/10.21228/M8770G
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN002202 AN002203
Analysis type MS MS
Chromatography type HILIC HILIC
Chromatography system Agilent 1290 Agilent 1290
Column Waters Acquity UPLC BEH Amide (100 x 2.1mm, 1.7µm) Waters Acquity UPLC BEH Amide (100 x 2.1mm, 1.7µm)
MS Type ESI ESI
MS instrument type QTOF QTOF
MS instrument name ABI Sciex 5600 TripleTOF ABI Sciex 5600 TripleTOF
Ion Mode POSITIVE NEGATIVE
Units mV*s mV*min

MS:

MS ID:MS002048
Analysis ID:AN002202
Instrument Name:ABI Sciex 5600 TripleTOF
Instrument Type:QTOF
MS Type:ESI
MS Comments:MS raw data files were converted to the mzXML format using ProteoWizard, and processed by R package XCMS (version 3.2). The preprocessing results generated a data matrix that consisted of the retention time, mass-to-charge ratio (m/z) values, and peak intensity. R package CAMERA was used for peak annotation after XCMS data processing.
Ion Mode:POSITIVE
  
MS ID:MS002049
Analysis ID:AN002203
Instrument Name:ABI Sciex 5600 TripleTOF
Instrument Type:QTOF
MS Type:ESI
MS Comments:MS raw data files were converted to the mzXML format using ProteoWizard, and processed by R package XCMS (version 3.2). The preprocessing results generated a data matrix that consisted of the retention time, mass-to-charge ratio (m/z) values, and peak intensity. R package CAMERA was used for peak annotation after XCMS data processing.
Ion Mode:NEGATIVE
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