Summary of Study ST002088

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001048. The data can be accessed directly via it's Project DOI: 10.21228/M87D6G This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)
Study IDST002088
Study TitlePlasma Metabolomic signatures of COPD in a SPIROMICS cohort: A metabolomic severity score for airflow obstructions and emphysema
Study TypeObservational Cohort
Study SummaryPlasma Metabolomic signatures of COPD in a SPIROMICS cohort The Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) (ClinicalTrials.gov Identifier: NCT01969344) includes 2,771 subjects, aged 40-80 years with at least 20 pack-years of smoking. An additional 202 subjects were never smokers. Fasting blood drawn at the enrollment visit using a p100 tube. The first 648 subjects who returned for a 5-7 year visit (Visit 5) were selected for this study. The blood profiled were from the year 1 visit. This study is a duplicate of ST001639 (https://www.metabolomicsworkbench.org/data/DRCCMetadata.php?Mode=Study&StudyID=ST001639) but differs in analysis and contains batch normalized data using median metabolite values.
Institute
National Jewish Health
DepartmentDivision of Pulmonary Medicine
LaboratoryBowler
Last NameBowler
First NameRussell
Address1400 Jackson St. Denver, CO 80206
Emailbowlerr@njhealth.org
Phone303 270 2014
Submit Date2022-02-14
Num Groups1
Total Subjects648
Analysis Type DetailLC-MS
Release Date2022-03-04
Release Version1
Russell Bowler Russell Bowler
https://dx.doi.org/10.21228/M87D6G
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Combined analysis:

Analysis ID AN003406 AN003407 AN003408 AN003409
Analysis type MS MS MS MS
Chromatography type Reversed phase Reversed phase Reversed phase HILIC
Chromatography system Waters Acquity Waters Acquity Waters Acquity Waters Acquity
Column Waters Acquity BEH C18 (100 x 2mm,1.7um) Waters Acquity BEH C18 (100 x 2mm,1.7um) Waters Acquity BEH C18 (100 x 2mm,1.7um) Waters Acquity BEH Amide (150 x 2.1mm,1.7um)
MS Type ESI ESI ESI ESI
MS instrument type Orbitrap Orbitrap Orbitrap Orbitrap
MS instrument name Thermo LTQ Thermo LTQ Thermo LTQ Thermo LTQ
Ion Mode POSITIVE POSITIVE NEGATIVE NEGATIVE
Units relativeMedian relativeMedian relativeMedian relativeMedian

MS:

MS ID:MS003171
Analysis ID:AN003406
Instrument Name:Thermo LTQ
Instrument Type:Orbitrap
MS Type:ESI
MS Comments:Proprietary analytical software for integration and peak picking
Ion Mode:POSITIVE
  
MS ID:MS003172
Analysis ID:AN003407
Instrument Name:Thermo LTQ
Instrument Type:Orbitrap
MS Type:ESI
MS Comments:Proprietary analytical software for integration and peak picking
Ion Mode:POSITIVE
  
MS ID:MS003173
Analysis ID:AN003408
Instrument Name:Thermo LTQ
Instrument Type:Orbitrap
MS Type:ESI
MS Comments:Proprietary analytical software for integration and peak picking
Ion Mode:NEGATIVE
  
MS ID:MS003174
Analysis ID:AN003409
Instrument Name:Thermo LTQ
Instrument Type:Orbitrap
MS Type:ESI
MS Comments:Proprietary analytical software for integration and peak picking
Ion Mode:NEGATIVE
  logo