Summary of Study ST002194
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001398. The data can be accessed directly via it's Project DOI: 10.21228/M8141Z This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002194 |
| Study Title | Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation |
| Study Summary | In this study CE-MS and GC-MS based metabolomics was used to analyze COVID-19 disease. In total, 144 individuals classified as healthy, asymptomatic/mils, moderate and severe according to the highest COVID-19 severity status, were analyzed. |
| Institute | CEMBIO |
| Last Name | Barbas |
| First Name | Coral |
| Address | CEU Universities, Urbanización Montepríncipe |
| cbarbas@ceu.es | |
| Phone | +34 913724700 |
| Submit Date | 2022-06-09 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Analysis Type Detail | GC-MS/LC-MS |
| Release Date | 2022-06-17 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN003591 | AN003592 |
|---|---|---|
| Analysis type | MS | MS |
| Chromatography type | CE | GC |
| Chromatography system | Agilent 7100 CE | 8890 |
| Column | silica capillary (100 cm; inner diameter,50um,Agilent Technologies) | Agilent DB5-MS (30m x 0.25mm, 0.25um) |
| MS Type | ESI | EI |
| MS instrument type | TOF | Single quadrupole |
| MS instrument name | Agilent CE-TOFMS | Agilent 5977B |
| Ion Mode | POSITIVE | UNSPECIFIED |
| Units | Peak Area | Corrected areas |
MS:
| MS ID: | MS003346 |
| Analysis ID: | AN003591 |
| Instrument Name: | Agilent CE-TOFMS |
| Instrument Type: | TOF |
| MS Type: | ESI |
| MS Comments: | Data were acquired in positive ionization polarity with a full scan range from 70 to 1000 m/z at a rate of 1.36 scan/s. The rest of MS conditions were: fragmentor set to 125 V, skimmer to 65 V, OCT RF Vpp to 750 V, drying gas temperature to 200 °C, flow rate to 10 L/min, nebulizer to 10 psig, and capillary voltage to 3500 V. The sheath liquid used for detection contained two reference masses (5 µL of purine with m/z 121.0509 and 5 µL of HP-0921 with m/z 922.0098) in MeOH/water (1/1; v/v) with 1 mM formic acid and the flow rate was set to 0.6 mL/min (split 1:100). The data acquisition was made using the Agilent MassHunter Workstation (Agilent Technologies). |
| Ion Mode: | POSITIVE |
| Analysis Protocol File: | Sample_Analysis.pdf |
| MS ID: | MS003347 |
| Analysis ID: | AN003592 |
| Instrument Name: | Agilent 5977B |
| Instrument Type: | Single quadrupole |
| MS Type: | EI |
| MS Comments: | The transfer line temperature was stablished at 280 °C and the electron ionization (EI) source was operated at 70 eV and the filament source temperature was set at 200 °C. Mass spectra were collected over a mass range of 50 - 600 m/z at a scan rate of 2.7 scans/s. Data were acquired using the Agilent MassHunter Workstation GC/MS Data Acquisition (version 10.0). |
| Ion Mode: | UNSPECIFIED |
| Analysis Protocol File: | Sample_Analysis.pdf |
