Summary of Study ST002194

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001398. The data can be accessed directly via it's Project DOI: 10.21228/M8141Z This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002194
Study TitleMetabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation
Study SummaryIn this study CE-MS and GC-MS based metabolomics was used to analyze COVID-19 disease. In total, 144 individuals classified as healthy, asymptomatic/mils, moderate and severe according to the highest COVID-19 severity status, were analyzed.
Last NameBarbas
First NameCoral
AddressCEU Universities, Urbanización Montepríncipe
Phone+34 913724700
Submit Date2022-06-09
Raw Data AvailableYes
Raw Data File Type(s)mzXML
Analysis Type DetailGC/LC-MS
Release Date2022-06-17
Release Version1
Coral Barbas Coral Barbas application/zip

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Combined analysis:

Analysis ID AN003591 AN003592
Analysis type MS MS
Chromatography type Other GC
Chromatography system Agilent 7100 CE 8890
Column silica capillary (100 cm; inner diameter, 50 µm, Agilent Technologies) Agilent DB5-MS (30m x 0.25mm, 0.25um)
MS instrument type TOF Single quadrupole
MS instrument name Agilent CE-TOFMS Agilent 5977B
Units Peak Area Corrected areas


MS ID:MS003346
Analysis ID:AN003591
Instrument Name:Agilent CE-TOFMS
Instrument Type:TOF
MS Comments:Data were acquired in positive ionization polarity with a full scan range from 70 to 1000 m/z at a rate of 1.36 scan/s. The rest of MS conditions were: fragmentor set to 125 V, skimmer to 65 V, OCT RF Vpp to 750 V, drying gas temperature to 200 °C, flow rate to 10 L/min, nebulizer to 10 psig, and capillary voltage to 3500 V. The sheath liquid used for detection contained two reference masses (5 µL of purine with m/z 121.0509 and 5 µL of HP-0921 with m/z 922.0098) in MeOH/water (1/1; v/v) with 1 mM formic acid and the flow rate was set to 0.6 mL/min (split 1:100). The data acquisition was made using the Agilent MassHunter Workstation (Agilent Technologies).
Analysis Protocol File:Sample_Analysis.pdf
MS ID:MS003347
Analysis ID:AN003592
Instrument Name:Agilent 5977B
Instrument Type:Single quadrupole
MS Type:EI
MS Comments:The transfer line temperature was stablished at 280 °C and the electron ionization (EI) source was operated at 70 eV and the filament source temperature was set at 200 °C. Mass spectra were collected over a mass range of 50 - 600 m/z at a scan rate of 2.7 scans/s. Data were acquired using the Agilent MassHunter Workstation GC/MS Data Acquisition (version 10.0).
Analysis Protocol File:Sample_Analysis.pdf