Summary of Study ST001253
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000840. The data can be accessed directly via it's Project DOI: 10.21228/M83Q36 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001253 |
| Study Title | Phenotyping Mouse blood metabolites in day and night in type 2 diabetes |
| Study Type | time course in a 24hr period |
| Study Summary | This experiment compares the metabolites in control db/m and diabetic db/db in day and night. |
| Institute | Indiana University School of Medicine |
| Department | Ophthalmology |
| Laboratory | Maria Grant Laboratory |
| Last Name | Beli |
| First Name | Eleni |
| Address | 97 Lisburn Road |
| e.beli@qub.ac.uk | |
| Phone | 5176144409 |
| Submit Date | 2019-09-24 |
| Num Groups | 4 |
| Total Subjects | 15 |
| Num Males | 15 |
| Publications | Nutrients.2019. Beli E. Loss of diurnal oscillatory rhythms in gut microbiota correlates with changes in circulating metabolites in type 2 diabetic, db/db mice |
| Raw Data Available | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2019-10-11 |
| Release Version | 1 |
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Project:
| Project ID: | PR000840 |
| Project DOI: | doi: 10.21228/M83Q36 |
| Project Title: | Phenotyping blood metabolites in day and night in type 2 diabetes |
| Project Summary: | Our hypothesis is that diabetes leads to differential regulation of circulating metabolites during the day and the night. We performed an untargeted global metabolomics study of plasma murine samples collected from 10-month old control (db/m) and type 2 diabetic (db/db) mice (n=3). Plasma was collected in EDTA tubes at a day (ZT5) and at a night (ZT17) timepoint and was frozen. Samples were shipped on dry ice and analyzed by Metabolon Inc with their untargeted global metabolomic platform and using UPLC- MS/MS to detect metabolites. |
| Institute: | Indiana University School of Medicine |
| Department: | Ophthalmology |
| Laboratory: | Maria Grant Laboratory |
| Last Name: | Beli |
| First Name: | Eleni |
| Address: | 97 Lisburn Road |
| Email: | e.beli@qub.ac.uk |
| Phone: | 2890976461 |
| Funding Source: | NIH- NIE |
| Publications: | Nutrients.2019. Beli E. Loss of diurnal oscillatory rhythms in gut microbiota correlates with changes in circulating metabolites in type 2 diabetic, db/db mice |
