Summary of Study ST001795
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001139. The data can be accessed directly via it's Project DOI: 10.21228/M8GH59 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001795 |
| Study Title | Changes in mesenteric lymph lipid profile of mice upon high-fat diet with and without Celecoxib (part I) |
| Study Type | Untargeted lipidomics analysis |
| Study Summary | Untargeted lipid profiling of mesenteric mice lymph from mice fed with CHOW, HFD and HFD supplemented with COx-2 inhibitor drug Celecoxib. It is proposed that Celecoxib can protect from deleterious morphological changes in lymphatic system caused by obesity/HFD. |
| Institute | Monash Institute of Pharmaceutical Sciences |
| Department | Drug Delivery, Disposition and Dynamics |
| Laboratory | Trevaskis Lab, Creek Lab |
| Last Name | Anderson |
| First Name | Dovile |
| Address | 6 Anderson |
| dovile.anderson@gmail.com | |
| Phone | 8671141 |
| Submit Date | 2021-05-12 |
| Num Groups | 3 |
| Total Subjects | 26 |
| Num Males | 26 |
| Publications | Manuscript NATMETAB-A20022406A Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential novel treatment target in obesity |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-06-02 |
| Release Version | 1 |
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Project:
| Project ID: | PR001139 |
| Project DOI: | doi: 10.21228/M8GH59 |
| Project Title: | Changes in mesenteric lymph lipid profile of mice upon high-fat diet with and without Celecoxib |
| Project Type: | Untargeted lipidomics |
| Project Summary: | Untargeted lipidomic profiling of mice mesenteric lymph upon HFD diet and HFD supplemented with COX-2 inhibitor drug Celecoxib. It is proposed that Celecoxib can rescue from negative morphological changes induced by obesity/HFD diet in lymphatic system. |
| Institute: | Monash Institute of Pharmaceutical Sciences |
| Department: | Drug Delivery, Disposition and Dynamics |
| Laboratory: | Trevaskis Lab, Creek Lab |
| Last Name: | Anderson |
| First Name: | Dovile |
| Address: | 399 Royal Pd |
| Email: | dovile.anderson@monash.edu |
| Phone: | +61448671141 |
| Funding Source: | Department of Health | National Health and Medical Research Council (NHMRC) - 1100036 [Trevaskis] |
| Project Comments: | This lipidomics project is part of a larger obesity/lymph research as described in the manuscript |
| Publications: | Manuscript NATMETAB-A20022406A Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential novel treatment target in obesity |
| Contributors: | Dr Enyuan Cao , Matthew Watt , Cameron Nowell , Dr Tim Quach , Jamie Simpson , Ms Violena Ferreira , Sonya Argawal , Hannah Chu , Anubhav Srivastava , Dr Dovile Anderson , Gracia Gracia , Alina Lam , Gabriela Segal , Jiwon Hong , Dr Luojuan Hu , Kian Lium Phang , Alistair Escott , Professor John Windsor , Anthony Phillips , Darren Creek , Professor Natasha Harvey , Professor Christopher Porter |
