Summary of Study ST001949
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001236. The data can be accessed directly via it's Project DOI: 10.21228/M8Z10X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001949 |
| Study Title | Plasma Metabolome Normalization in Rheumatoid Arthritis following initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy |
| Study Type | Clinical |
| Study Summary | Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response to MTX in RA with the goal of understanding the metabolic basis for MTX efficacy towards the identification of potential metabolic biomarkers of MTX response. |
| Institute | University of Kansas |
| Department | Pharmacy Practice |
| Laboratory | Funk |
| Last Name | Medcalf |
| First Name | Matthew |
| Address | 2106 Olathe Boulevard |
| mmedcalf@ku.edu | |
| Phone | 13147880236 |
| Submit Date | 2021-10-20 |
| Num Groups | 3 |
| Total Subjects | 40 |
| Num Males | 9 |
| Num Females | 31 |
| Raw Data Available | Yes |
| Analysis Type Detail | GC-MS |
| Release Date | 2022-11-07 |
| Release Version | 1 |
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Project:
| Project ID: | PR001236 |
| Project DOI: | doi: 10.21228/M8Z10X |
| Project Title: | Plasma Metabolome Normalization in Rheumatoid Arthritis following initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy |
| Project Type: | Clinical |
| Project Summary: | Methotrexate (MTX) efficacy in the treatment of rheumatoid arthritis (RA) is variable and unpredictable, resulting in a need to identify biomarkers to guide drug therapy. This study evaluates changes in the plasma metabolome associated with response to MTX in RA with the goal of understanding the metabolic basis for MTX efficacy towards the identification of potential metabolic biomarkers of MTX response. |
| Institute: | University of Kansas |
| Department: | Pharmacy Practice |
| Laboratory: | Funk |
| Last Name: | Medcalf |
| First Name: | Matthew |
| Address: | 2106 Olathe Boulevard |
| Email: | mmedcalf@ku.edu |
| Phone: | 13147880236 |
| Funding Source: | KL2TR002367 |
