Summary of Study ST002088
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001048. The data can be accessed directly via it's Project DOI: 10.21228/M87D6G This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST002088 |
| Study Title | Plasma Metabolomic signatures of COPD in a SPIROMICS cohort: A metabolomic severity score for airflow obstructions and emphysema |
| Study Type | Observational Cohort |
| Study Summary | Plasma Metabolomic signatures of COPD in a SPIROMICS cohort The Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) (ClinicalTrials.gov Identifier: NCT01969344) includes 2,771 subjects, aged 40-80 years with at least 20 pack-years of smoking. An additional 202 subjects were never smokers. Fasting blood drawn at the enrollment visit using a p100 tube. The first 648 subjects who returned for a 5-7 year visit (Visit 5) were selected for this study. The blood profiled were from the year 1 visit. This study is a duplicate of ST001639 (https://www.metabolomicsworkbench.org/data/DRCCMetadata.php?Mode=Study&StudyID=ST001639) but differs in analysis and contains batch normalized data using median metabolite values. |
| Institute | National Jewish Health |
| Department | Division of Pulmonary Medicine |
| Laboratory | Bowler |
| Last Name | Bowler |
| First Name | Russell |
| Address | 1400 Jackson St. Denver, CO 80206 |
| bowlerr@njhealth.org | |
| Phone | 303 270 2014 |
| Submit Date | 2022-02-14 |
| Num Groups | 1 |
| Total Subjects | 648 |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-03-04 |
| Release Version | 1 |
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Project:
| Project ID: | PR001048 |
| Project DOI: | doi: 10.21228/M87D6G |
| Project Title: | Plasma Metabolomic signatures of COPD in a SPIROMICS cohort |
| Project Summary: | The Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) (ClinicalTrials.gov Identifier: NCT01969344) includes 2,771 subjects, aged 40-80 years with at least 20 pack-years of smoking. An additional 202 subjects were never smokers. Fasting blood drawn at the enrollment visit using a p100 tube. The first 649 subjects who returned for a 5-7 year visit (Visit 5) were selected for this study. The blood profiled were from the year 1 visit. |
| Institute: | National Jewish Health |
| Department: | Division of Pulmonary Medicine |
| Laboratory: | Bowler |
| Last Name: | Bowler |
| First Name: | Russell |
| Address: | 1400 Jackson St. Denver, CO 80206 |
| Email: | bowlerr@njhealth.org |
| Phone: | 303 270 2014 |
| Funding Source: | NHLBI R21 HL140376, R01HL129937, R01HL 095432, R01 HL089856, R01 HL089897); and UL1 RR025680 from NCRR/HIH |
