Summary of Study ST002149
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001362. The data can be accessed directly via it's Project DOI: 10.21228/M8NX37 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002149 |
Study Title | In vivo commensal control of Clostridioides difficile virulence |
Study Type | Gnotobiotic mouse infection model |
Study Summary | Gnotobiotic mouse infection model with C. difficile strain ATCC43255 and co-colonization studies with the commensals Paraclostridium bifermentans or Clostridium sardiniense |
Institute | Brigham and Women's Hospital |
Department | Pathology/Massachusetts Host-Microbiome Center |
Laboratory | Bry |
Last Name | Bry |
First Name | Lynn |
Address | 221 Longwood Ave |
lbry@bwh.harvard.edu | |
Phone | 6177325500 |
Submit Date | 2021-12-09 |
Num Groups | 6 |
Total Subjects | 48 |
Num Males | 24 |
Num Females | 24 |
Publications | doi: 10.1016/j.chom.2021.09.007 |
Analysis Type Detail | LC-MS |
Release Date | 2022-05-13 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
Project ID: | PR001362 |
Project DOI: | doi: 10.21228/M8NX37 |
Project Title: | In vivo commensal control of Clostrioides difficile virulence |
Project Type: | Animal model |
Project Summary: | Untargeted metabolomic data (Metabolon) of cecal contents from gnotobiotic (GF) mice, GF mice monocolonized for 7 days with the commensals Paraclostridium bifermentans or Clostridium sardiniens, or for 24 hours with C. difficile strain ATCC43255 or co-colonized with one of the above commensals. |
Institute: | Brigham and Women's Hospital |
Department: | Pathology/Massachusetts Host-Microbiome Center |
Laboratory: | Bry |
Last Name: | Bry |
First Name: | Lynn |
Address: | 221 Longwood Ave |
Email: | lbry@bwh.harvard.edu |
Phone: | 6177325500 |
Funding Source: | BWH Precision Medicine Institute; NIH: R01 AI153605, P30DK034854, R01AI128215, R01AI141953, U19AI135976 T32 HL007627; NSF: IIBR-2042948; Pasteur Bourse ROUX |
Publications: | doi:10.1016/j.chom.2021.09.007 doi:10.1016/j.chom.2021.09.008 |