Summary of Study ST002149

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001362. The data can be accessed directly via it's Project DOI: 10.21228/M8NX37 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002149
Study TitleIn vivo commensal control of Clostridioides difficile virulence
Study TypeGnotobiotic mouse infection model
Study SummaryGnotobiotic mouse infection model with C. difficile strain ATCC43255 and co-colonization studies with the commensals Paraclostridium bifermentans or Clostridium sardiniense
Brigham and Women's Hospital
DepartmentPathology/Massachusetts Host-Microbiome Center
Last NameBry
First NameLynn
Address221 Longwood Ave
Submit Date2021-12-09
Num Groups6
Total Subjects48
Num Males24
Num Females24
Publicationsdoi: 10.1016/j.chom.2021.09.007
Analysis Type DetailUnspecified
Release Date2022-05-13
Release Version1
Lynn Bry Lynn Bry application/zip

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Project ID:PR001362
Project DOI:doi: 10.21228/M8NX37
Project Title:In vivo commensal control of Clostrioides difficile virulence
Project Type:Animal model
Project Summary:Untargeted metabolomic data (Metabolon) of cecal contents from gnotobiotic (GF) mice, GF mice monocolonized for 7 days with the commensals Paraclostridium bifermentans or Clostridium sardiniens, or for 24 hours with C. difficile strain ATCC43255 or co-colonized with one of the above commensals.
Institute:Brigham and Women's Hospital
Department:Pathology/Massachusetts Host-Microbiome Center
Last Name:Bry
First Name:Lynn
Address:221 Longwood Ave
Funding Source:BWH Precision Medicine Institute; NIH: R01 AI153605, P30DK034854, R01AI128215, R01AI141953, U19AI135976 T32 HL007627; NSF: IIBR-2042948; Pasteur Bourse ROUX
Publications:doi:10.1016/j.chom.2021.09.007 doi:10.1016/j.chom.2021.09.008