Summary of Study ST002197

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001400. The data can be accessed directly via it's Project DOI: 10.21228/M8RM5T This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002197
Study TitleMetabolic signature of C-protein induced myositis mouse model
Study SummaryObjective of this study was to find Metabolic signature of C-protein induced myositis mouse model. For metabolite quantification, we used the tissue samples of C-protein induced myositis mouse model and control. Biocrates p180 kit enables to quantify 188 metabolites including amino acids, biogenic amines, acylcarnitine, glycerophospholipid and sugar. Significant metabolites were selected by t-test with false discovery rate p-value less than 0.05. In mouse tissue sample, a total of 68 metabolites significantly changed in CIM mice. We did pathway analysis to find altered pathway in muscle tissue. Metabolites from polyamine and beta-alanine pathway were altered.
Institute
Seoul National University
Last NameKang
First NameJihyun
Address502ho Intergrative Biomedical Education Research Building, 101 Deahakro, Jongro-gu, Seoul, 03080, Korea, South Korea
Emailjikang@snu.ac.kr
Phone+821071014069
Submit Date2022-06-15
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2022-07-14
Release Version1
Jihyun Kang Jihyun Kang
https://dx.doi.org/10.21228/M8RM5T
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR001400
Project DOI:doi: 10.21228/M8RM5T
Project Title:Myositis metabolomics
Project Type:MS quantitative analysis
Project Summary:Targeted metabolomics study for idiopathic inflammatory myositis patients and C-protein induced myositis mouse model
Institute:Seoul national university
Last Name:Kang
First Name:Jihyun
Address:502ho Intergrative Biomedical Education Research Building, 101 Deahakro, Jongro-gu, Seoul, 03080, Korea, South
Email:jikang@snu.ac.kr
Phone:+821071014069
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