Summary of Study ST001815

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001148. The data can be accessed directly via it's Project DOI: 10.21228/M89Q5T This work is supported by NIH grant, U2C- DK119886.

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Study ID	ST001815
Study Title	Metabolic Markers of Methotrexate Response in Juvenile Idiopathic Arthritis
Study Type	Clinical
Study Summary	Plasma from children with juvenile idiopathic arthritis collected pre-treatment and following 3 months of treatment with methotrexate were submitted for metabolomic profiling to the NIH West Coast Metabolomics Center.
Institute	University of Kansas
Department	Pharmacy Practice
Laboratory	Funk Lab
Last Name	funk
First Name	ryan
Address	2106 Olathe Boulevard
Email	ryanfunk@kumc.edu
Phone	9135885000
Submit Date	2021-05-18
Num Groups	1
Total Subjects	30
Num Males	9
Num Females	21
Analysis Type Detail	GC-MS/LC-MS
Release Date	2021-06-17
Release Version	1

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Sample Preparation:

Sampleprep ID:	SP001898
Sampleprep Summary:	Plasma samples were sent to the West Coast Metabolomics Center and were processed on laboratory Standard Operating Procedures for Sample Preparation of Blood Plasma or Serum Samples for Lipidomic, Biogenic Amine, and Primary Metabolomic Analysis using a biphasic MeOH/MTBE/Water extraction procedure. The upper organic phase was used for lipidomics analysis and the aqueous phase was used for analysis of primary metabolism and biogenic amines.

Sampleprep ID:

SP001898

Sampleprep Summary:

Plasma samples were sent to the West Coast Metabolomics Center and were processed on laboratory Standard Operating Procedures for Sample Preparation of Blood Plasma or Serum Samples for Lipidomic, Biogenic Amine, and Primary Metabolomic Analysis using a biphasic MeOH/MTBE/Water extraction procedure. The upper organic phase was used for lipidomics analysis and the aqueous phase was used for analysis of primary metabolism and biogenic amines.