Summary of Study ST001940
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001228. The data can be accessed directly via it's Project DOI: 10.21228/M80120 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001940 |
| Study Title | Cognitive Behavioral Therapy for Irritable Bowel Syndrome Induces Bidirectional Alterations in the Brain-Gut-Microbiome Axis Associated with Gastrointestinal Symptom Improvement |
| Study Summary | 34 Rome III-diagnosed IBS patients receiving CBT were drawn from the Irritable Bowel Syndrome Outcome Study (IBSOS; ClinicalTrials.gov NCT00738920). Fecal samples were collected at baseline and post-treatment for 16S rRNA gene sequencing, untargeted metabolomics, and measurement of short chain fatty acids. Multimodal neuroimaging was performed at baseline and post-treatment. |
| Institute | University of California, Los Angeles |
| Department | Division of Digestive Diseases |
| Laboratory | Jacobs Laboratory |
| Last Name | Jacobs |
| First Name | Jonathan |
| Address | 10833 Le Conte Ave, Los Angeles, CA 90095 |
| JJacobs@mednet.ucla.edu | |
| Phone | 310-825-9333 |
| Submit Date | 2021-09-01 |
| Total Subjects | 34 |
| Num Males | 6 |
| Num Females | 28 |
| Raw Data Available | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-03-01 |
| Release Version | 1 |
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Sample Preparation:
| Sampleprep ID: | SP002024 |
| Sampleprep Summary: | Aliquots of frozen feces were shipped to Metabolon, Inc., and run as a single batch on their global HD4 metabolomics platform. |
