Summary of Study ST001940

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001228. The data can be accessed directly via it's Project DOI: 10.21228/M80120 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001940
Study TitleCognitive Behavioral Therapy for Irritable Bowel Syndrome Induces Bidirectional Alterations in the Brain-Gut-Microbiome Axis Associated with Gastrointestinal Symptom Improvement
Study Summary34 Rome III-diagnosed IBS patients receiving CBT were drawn from the Irritable Bowel Syndrome Outcome Study (IBSOS; ClinicalTrials.gov NCT00738920). Fecal samples were collected at baseline and post-treatment for 16S rRNA gene sequencing, untargeted metabolomics, and measurement of short chain fatty acids. Multimodal neuroimaging was performed at baseline and post-treatment.
Institute
University of California, Los Angeles
DepartmentDivision of Digestive Diseases
LaboratoryJacobs Laboratory
Last NameJacobs
First NameJonathan
Address10833 Le Conte Ave, Los Angeles, CA 90095
EmailJJacobs@mednet.ucla.edu
Phone310-825-9333
Submit Date2021-09-01
Total Subjects34
Num Males6
Num Females28
Raw Data AvailableYes
Analysis Type DetailLC-MS
Release Date2022-03-01
Release Version1
Jonathan Jacobs Jonathan Jacobs
https://dx.doi.org/10.21228/M80120
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Sample Preparation:

Sampleprep ID:SP002024
Sampleprep Summary:Aliquots of frozen feces were shipped to Metabolon, Inc., and run as a single batch on their global HD4 metabolomics platform.
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