Summary of Study ST001953

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001240. The data can be accessed directly via it's Project DOI: 10.21228/M8F121 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001953
Study TitleIdentifying metabolite changes in human islets treated with Phospho-BAD mimicry and Inflammatory cytokines
Study SummaryThe goal of this study was to associate metabolite changes with protection of human islets from cell death induced by the diabetogenic stress of inflammatory cytokines. Protection of human islet viability was accomplished via enhanced glucose metabolism using phospho-BAD mimicry peptide treatment.
Institute
Harvard University
DepartmentDana-Farber Cancer Institute
LaboratoryNika N. Danial
Last NameFu
First NameAccalia
Address360 Longwood Ave., Boston, MA, 02215
Emailaccalia_fu@dfci.harvard.edu
Phone617-632-3000
Submit Date2021-10-18
Num Groups4
Total Subjects32
PublicationsFu et al. 2020, Fu et al. in press
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2021-11-12
Release Version1
Accalia Fu Accalia Fu
https://dx.doi.org/10.21228/M8F121
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Sample Preparation:

Sampleprep ID:SP002037
Sampleprep Summary:150 human islets per replicate were extracted in hot 70% ethanol at 75˚C for 3 min, placed on ice, and clarified by centrifugation. Extracts from all donors were pooled and analyzed in 8 replicates by flow-injections.
Sampleprep Protocol Filename:Methods Fu et al. FIA_MS
Extraction Method:Islet were extracted with hot 70% ethanol at 75˚C for 3 min
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