Summary of Study ST000903

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000627. The data can be accessed directly via it's Project DOI: 10.21228/M8MT2H This work is supported by NIH grant, U2C- DK119886.

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Study IDST000903
Study TitlePharmacometabolomic analysis of rat hippocampus and plasma in response to chronic stress and albiflorin treament
Study TypeAnimal study
Study SummaryMale Sprague-Dawley (SD) rats were exposed to one random stressor per day for 35 d. Following four weeks of stress exposure, rats with stress-induced depression-like behaviors were treated daily with either saline, fluoxetine or albiflorin for 7 days via intragastric gavage. Rat heparinized plasma was collected after drug treatment. After behavior tests, rats were sacrificed and the hippocampus was collected. Pharmacometabolomic analysis was conducted for both plasma and hippocampal samples
Institute
Beijing Wonner Biotech. Ltd. Co.
Last NameZhang
First NameZuoguang
AddressNo.9, Kexing Road, Fengtai, Beijing, Beijing, 101111, China
Emailleekefeng@hotmail.com
Phone86-10-65670787
Submit Date2017-11-16
Num Groups4
Study CommentsAnimal study
Analysis Type DetailLC-MS
Release Date2018-02-07
Release Version1
Zuoguang Zhang Zuoguang Zhang
https://dx.doi.org/10.21228/M8MT2H
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Subject:

Subject ID:SU000940
Subject Type:Animal
Subject Species:Rattus norvegicus
Taxonomy ID:10116
Genotype Strain:Sprague-Dawley
Weight Or Weight Range:180-220 g
Gender:Male
Animal Animal Supplier:Beijing Huafukang Bioscience
Animal Light Cycle:12:12 light-dark cycle
Animal Feed:Standard food
Animal Water:Free access to food and water
Species Group:Mammal
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