Summary of Study ST001179

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000791. The data can be accessed directly via it's Project DOI: 10.21228/M8F97P This work is supported by NIH grant, U2C- DK119886.


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Study IDST001179
Study TitleMetabolomic analysis of skeletal muscle in young and aged mice
Study SummarySarcopenia is the age-induced, progressive loss of skeletal muscle mass and function, which results in poor muscle performance. To better understand changes in skeletal muscles during sarcopenia, we performed a metabolomic analysis of skeletal muscle in young (8-week-old) and aged (28-month-old) mice using CE-TOFMS. Our data shows that the metabolites including glucose and polyamine metabolism were decreased in aged mice compared with young mice. In addition, neurotransmitter levels were higher in aged mice.
Kyoto Prefectural University
Last NameKamei
First NameYasutomi
Address1-5 Hangi-cho, Shimogamo, Sakyo-ku Kyoto, Kyoto, Kyoto, 606-8522, Japan
Submit Date2019-05-06
Analysis Type DetailLC-MS
Release Date2019-07-17
Release Version1
Yasutomi Kamei Yasutomi Kamei application/zip

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Subject ID:SU001245
Subject Type:Mammal
Subject Species:Mus musculus
Taxonomy ID:10090
Genotype Strain:wild type
Age Or Age Range:8-week-old and 28-month-old
Weight Or Weight Range:25.4 ± 0.2 g for young and 32.0 ± 0.2 g for aged
Animal Animal Supplier:Shimizu Laboratory Supplies (Kyoto, Japan)
Animal Light Cycle:12-h light-dark cycle
Animal Feed:CE2
Species Group:C57BL/6J