Summary of Study ST001400
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000960. The data can be accessed directly via it's Project DOI: 10.21228/M8M39X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001400 |
| Study Title | Identification of distinct metabolic perturbations and associated immunomodulatory events during intra-erythrocytic development stage of pediatric Plasmodium falciparum malaria |
| Study Summary | The goal of this study was to interrogate biochemical profiles manifested in human serum samples originating from a cohort of West African children, collected before and during P. falciparum malarial infection, with the aim of characterizing metabolic migration associated with severity of malarial infection. |
| Institute | New York University Abu Dhabi |
| Last Name | Abdrabou |
| First Name | Wael |
| Address | Saadiyat Island, P.O Box 129188, Abu Dhabi |
| wsa224@nyu.edu | |
| Phone | 0562729855 |
| Submit Date | 2020-06-15 |
| Num Groups | 2 |
| Total Subjects | 200 |
| Num Males | 109 |
| Num Females | 90 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-08-10 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Subject:
| Subject ID: | SU001474 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 2-12 years |
| Weight Or Weight Range: | 11-30 Kilograms |
| Height Or Height Range: | 85 - 137 cm |
| Gender: | Male and female |
| Human Ethnicity: | Gouin (Burkina Faso, West Africa) |
| Human Inclusion Criteria: | residency in the Nafona- and Bounouna rural area in Burkina Faso, age of 2 to 12 years, no P. falciparum infection at the time of enrollment (as evidenced by malaria rapid diagnostic test and confirmed later with microscopy and qPCR), no fever (axillary temperature ≥37.5°C) or history of fever within the preceding 48 hours |
| Human Exclusion Criteria: | history of immunosuppressive diseases or chronic diseases, signs of concomitant febrile illness or active infection, use of anti-malarial treatment within the preceding two weeks, use of immunosuppressant or other immune-modifying drugs within the preceding six months and receiving blood transfusion within the preceding three months |
