Summary of Study ST001856
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001170. The data can be accessed directly via it's Project DOI: 10.21228/M8G98C This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001856 |
| Study Title | The metabolomic resetting effect of FG4592 in AKI to CKD transition (Part 2) |
| Study Summary | C57BL/6 mice were anesthetized using isoflurane. UIR was induced by clamping the right renal pedicle for 45 minutes and then releasing it to allow reperfusion, leaving the left kidney intact. Sham treated mice served as controls. Each mouse was located supine on a thermostatic pad (37 °C) to maintain its body temperature throughout the whole process. After 3 days of recovery, the mice received a daily intraperitoneal (i.p.) injection of FG4592 (10 mg/kg) or vehicle for 7 consecutive days. After treatment, the mice were sacrificed.Non-target metabolomics analysis was carried out using the kidney tissues of mice sacrificed at day 10 after UIR. |
| Institute | Children's Hospital of Nanjing Medical University |
| Last Name | Weiyi |
| First Name | Chen |
| Address | 72 Guangzhou Road, Nanjing 210008, P. R. of China |
| chen.weiyi@qq.com | |
| Phone | +862583117309 |
| Submit Date | 2021-07-01 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-07-07 |
| Release Version | 1 |
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Subject:
| Subject ID: | SU001933 |
| Subject Type: | Mammal |
| Subject Species: | Mus musculus |
| Taxonomy ID: | 10090 |
| Genotype Strain: | C57BL/6 |
| Age Or Age Range: | 8 weeks |
| Weight Or Weight Range: | 20-25 g |
| Gender: | Male |
| Animal Animal Supplier: | Model Animal Research Center of Nanjing University |
| Animal Housing: | Standard specific pathogen free (SPF) conditions |
| Animal Light Cycle: | 12:12-h light/dark cycle |
| Animal Feed: | food freely |
| Animal Water: | water freely |
