Summary of Study ST000045

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000044. The data can be accessed directly via it's Project DOI: 10.21228/M8D59R This work is supported by NIH grant, U2C- DK119886.

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Study IDST000045
Study TitlePlasma metabolomics: Comparison of non-diabetic controls with T1D patients
Study TypeDrug effect study
Study SummaryNon-diabetic controls whose metabolites were compared to T1D patients with and without insulin. Seven C-peptide–negative T1D subjects were studied on two occasions: one during insulin treatment and the other following withdrawal of insulin for 8 h and compared with matched healthy ND participants
Institute
Mayo Clinic
DepartmentEndocrinology
Last NameNair
First NameSreekumaran
EmailDasari.Surendra@mayo.edu
Submit Date2014-03-24
Num Groups1
Total Subjects7
Raw Data AvailableYes
Raw Data File Type(s)d
Uploaded File Size66 G
Analysis Type DetailLC-MS
Release Date2014-04-20
Release Version1
Sreekumaran Nair Sreekumaran Nair
https://dx.doi.org/10.21228/M8D59R
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR000064
Treatment Summary:Saline Infusion | Insulin Withdrawal | Insulin Infusion
Treatment Protocol ID:SI / IW / II
Treatment Protocol Comments:ND participants were kept on a saline infusion from the evening following their meal. | Insulin was discontinued for 8.6 +/- 0.6 h starting at 0400 h. | Insulin was infused into a forearm vein to maintain blood glucose between 4.44 and 5.56 mmol | L overnight until 1200 h the next day.
Treatment Compound:Saline | Insulin
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