Summary of Study ST001110

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000741. The data can be accessed directly via it's Project DOI: 10.21228/M8WQ2Z This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001110
Study TitleInvestigating link between metabolism and circadian rhythm in Drosophila melanogaster
Study SummaryWe are investigating the link between metabolism, circadian rhythm, and a high-fat diet with an emphasis on the role of metabolites that affect protein post translational modifications. We've hypothesized that protein modifications, which are critical to circadian clock functions, can be affected by different metabolic profiles, such as an excess or lack of fat in the diet, that ultimately regulate changes in circadian biology.
Institute
University of California, Davis
DepartmentCollege of Biological Sciences
Last NameContreras
First NameAdam
Address202 Life Sciences Building, Kleiber Hall Drive, Davis, CA, 95616
Emailajcon@ucdavis.edu
Phone512-393-4773
Submit Date2018-10-19
Total Subjects96
Raw Data AvailableYes
Raw Data File Type(s)cdf
Analysis Type DetailGC-MS
Release Date2019-01-22
Release Version1
Adam Contreras Adam Contreras
https://dx.doi.org/10.21228/M8WQ2Z
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR001169
Treatment Summary:48 flies were split into two treatment groups, with 24 flies in each group. Group 1 consisted of a High Fat Diet (HFD, Cornmeal diet + 15% coconut oil) and Group 2 consisted of a Non-Fat Diet (NFD, Cornmeal). Within each group, flies were placed in one of four smaller groups, depending on how long they would be on either the HFD or NFD. These groups are ZT4, ZT10, ZT16, ZT22. Each of these smaller groups consisted of 6 flies, to create 4 groups of 6 flies each in both of the diet treatments.
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