Summary of Study ST001353
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000923. The data can be accessed directly via it's Project DOI: 10.21228/M8CT2B This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001353 |
| Study Title | Untargeted metabolomics in skeletal muscle of mice with chronic kidney disease |
| Study Type | MS quantitative analysis |
| Study Summary | This study performed untargeted metabolomics analysis of skeletal muscle obtained form mice with and without chronic kidney disease. |
| Institute | University of Florida |
| Last Name | Ryan |
| First Name | Terence |
| Address | 1864 Stadium Rd, FLG 114, Gainesville, FL, 32611, USA |
| ryant@ufl.edu | |
| Phone | 352-294-1700 |
| Submit Date | 2020-04-02 |
| Num Groups | 4 |
| Total Subjects | 18 |
| Num Males | 8 |
| Num Females | 10 |
| Study Comments | two control male samples processed mistakenly were from soles muscles, while all other samples were gastrocnemius muscles. Due to differences in fiber type proportions, soleus muscles were not used in final analysis |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Analysis Type Detail | LC-MS |
| Release Date | 2020-12-31 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR001442 |
| Treatment Summary: | We utilized an established adenine-diet model to induce CKD in mice. Mice were assigned to a casein-based chow diet for 7 days, followed by induction of renal tubular injury by supplementing the diet with 0.2% adenine for 7 days, and were subsequently maintained on a 0.15% adenine diet for 7 more weeks. CKD mice were then placed back on control casein diet for 2 weeks to prior to euthanasia and terminal experiments. Control mice received casein diet for the duration of the study. |
| Animal Anesthesia: | Ketamine/Xylazine |
| Animal Endp Euthanasia: | Ketamine/Xylazine |
