Summary of Study ST001361
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000931. The data can be accessed directly via it's Project DOI: 10.21228/M8BT4S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001361 |
| Study Title | Serum tryptophan metabolomics in CKD |
| Study Type | MS quantitative analysis |
| Study Summary | Serum was processed using a targeted metabolomics platform for quantifying tryptophan metabolites as a number of these metabolites are well establish uremic toxins. |
| Institute | University of Florida |
| Last Name | Ryan |
| First Name | Terence |
| Address | 1864 Stadium Rd, FLG 114, Gainesville, FL, 32611, USA |
| ryant@ufl.edu | |
| Phone | 352-294-1700 |
| Submit Date | 2020-04-02 |
| Num Groups | 2 |
| Total Subjects | 16 |
| Num Males | 8 |
| Num Females | 8 |
| Raw Data Available | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2020-12-31 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR001450 |
| Treatment Summary: | We utilized an established adenine-diet model to induce CKD in mice. Mice were assigned to a casein-based chow diet for 7 days, followed by induction of renal tubular injury by supplementing the diet with 0.2% adenine for 7 days, and were subsequently maintained on a 0.15% adenine diet for 7 more weeks. CKD mice were then placed back on control casein diet for 2 weeks to prior to euthanasia and terminal experiments. Control mice received casein diet for the duration of the study. |
| Animal Anesthesia: | Ketamine/Xylazine |
| Animal Endp Euthanasia: | Ketamine/Xylazine |
