Summary of Study ST002127

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001348. The data can be accessed directly via it's Project DOI: 10.21228/M8GD8D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002127
Study TitleAmino acids and TCA substrates in hematopoietic cells (Part4)
Study SummaryThis study uses [13C,15N] labeled amino acids to study the amino acid consumption and their catabolism into tricarboxylic acid cycle substrates in hematopoietic stem cells, hemopoietic progenitors, and differentiated hematopoietic cells under different conditions, such as homeostasis and proliferation and with drug treatment.
Institute
Sun Yat-sen University
Last NameZhao
First NameMeng
AddressZhongshan 2nd Road
Emailzhaom38@mail.sysu.edu.cn
Phone18138799889
Submit Date2022-04-06
Raw Data AvailableYes
Raw Data File Type(s)cdf
Analysis Type DetailGC-MS
Release Date2022-11-01
Release Version1
Meng Zhao Meng Zhao
https://dx.doi.org/10.21228/M8GD8D
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR002224
Treatment Summary:Germ-free C57BL/6J mice were intraperitoneally injected with 10 mg/kg 5FU (F6627-5G, Sigma-Aldrich) for 14 days, or fed with vehicle or NR (400 mg/kg per day) (1341-23-7, ziyi-reagent) for consecutive 8 weeks (long-term) or 1 week (short-term). Hematopoietic cells were stained and sorted from treated mice.
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