Summary of Study ST002149

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001362. The data can be accessed directly via it's Project DOI: 10.21228/M8NX37 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002149
Study TitleIn vivo commensal control of Clostridioides difficile virulence
Study TypeGnotobiotic mouse infection model
Study SummaryGnotobiotic mouse infection model with C. difficile strain ATCC43255 and co-colonization studies with the commensals Paraclostridium bifermentans or Clostridium sardiniense
Brigham and Women's Hospital
DepartmentPathology/Massachusetts Host-Microbiome Center
Last NameBry
First NameLynn
Address221 Longwood Ave
Submit Date2021-12-09
Num Groups6
Total Subjects48
Num Males24
Num Females24
Publicationsdoi: 10.1016/j.chom.2021.09.007
Analysis Type DetailUnspecified
Release Date2022-05-13
Release Version1
Lynn Bry Lynn Bry application/zip

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Treatment ID:TR002247
Treatment Summary:Gnotobiotic mice (baseline controls) or mono- or co-colonized with C. difficile, and the commensal P. bifermentans or C. sardiniense.
Treatment Dose:gavage with 1000 spores of ATCC43255 for C. difficile infection; 200uL of overnight culture for commensal species