Summary of Study ST004042
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002534. The data can be accessed directly via it's Project DOI: 10.21228/M83G11 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST004042 |
| Study Title | Untargeted Metabolomics Identifies Oncometabolites Induced by P2-HNF4α Overexpression in Hepatocytes |
| Study Summary | This study explores the metabolic impact of P2-HNF4α overexpression in primary mouse hepatocytes. Using untargeted metabolomics, we compared metabolite profiles between control and P2-HNF4α-overexpressing cells to identify metabolic pathways potentially altered in liver disease and HCC. |
| Institute | University of Tennessee Health Science Center |
| Department | IMM |
| Laboratory | Mahan Lab |
| Last Name | Fekry |
| First Name | Baharan |
| Address | 1825 Pressler St, Houston TX 77030. USA. |
| Baharan.Fekry@uth.tmc.edu | |
| Phone | 18434693199 |
| Submit Date | 2025-07-03 |
| Analysis Type Detail | LC-MS |
| Release Date | 2025-08-05 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR004197 |
| Treatment Summary: | Primary hepatocytes were isolated from mouse livers and cultured in vitro. Cells were transduced with either control GFP or P2-HNF4α-expressing lentivirus. Following 48 hours of transduction, cells were harvested and processed for untargeted metabolomics analysis. |
