Summary of study ST000004

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000004. The data can be accessed directly via it's Project DOI: 10.21228/M8MW26 This work is supported by NIH grant, U2C- DK119886.

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Study IDST000004
Study TitleLipidomics studies on NIDDK / NIST human plasma samples
Study TypeMS analysis on human plasma
Study SummaryThe National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in collaboration with the National Institute of Standards (NIST) recently produced a human plasma standard reference material (SRM 1950) for metabolite analysis. The SRM was prepared by obtaining plasma samples from 100 individuals between 40 and 50 years of age, whose ethnicity was representative of the US population and that included an equal number of men and women. The intent of the NIDDK/NIST project was to provide a reference material that would be publically available to researchers and that could be used by the clinical chemistry community to identify plasma metabolites for diagnostic purposes. Signature metabolites could then be further probed for their usefulness as disease biomarkers. The LIPID MAPS Consortium has undertaken the task to analyze this SRM by systematically identifying and quantifying the lipid molecular species in the six main categories of mammalian lipids. The quantitative levels of over 500 different lipids present in this reference human plasma sample are presented here.
Institute
LIPID MAPS
DepartmentMultiple
LaboratoryMultiple
Last NameFahy
First NameEoin
AddressUCSD
Emailefahy@ucsd.edu
Submit Date2013-02-20
Num Groups1
Total Subjects100
Num Males100
PublicationsQuehenberger, O. et al Lipidomics reveals a remarkable diversity of lipids in human plasma. J Lipid Res. 51, 3299-3305 (2010).
Raw Data AvailableNo
Analysis Type DetailLC-MS
Release Date2013-03-17
Release Version1
Eoin Fahy Eoin Fahy
https://dx.doi.org/10.21228/M8MW26
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:


Project:

Project ID:PR000004
Project DOI:doi: 10.21228/M8MW26
Project Title:LIPID MAPS Lipidomics studies
Project Type:MS quantitative analysis
Project Summary:Multi-center quantitative lipidomics studies on samples from human and murine sources (LIPIDMAPS)
Institute:LIPID MAPS
Department:Multiple
Laboratory:Multiple
Last Name:Fahy
First Name:Eoin
Address:UCSD
Email:efahy@ucsd.edu
Funding Source:NIGMS

Subject:

Subject ID:SU000005
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Age Or Age Range:40-50
Species Group:Human

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Pooled sample
SA000055NIDDK1yes
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Collection:

Collection ID:CO000004
Sample Type:Blood

Treatment:

Treatment ID:TR000006

Sample Preparation:

Sampleprep ID:SP000004

Combined analysis:

Analysis ID AN000004 AN000005 AN000006 AN000007 AN000008 AN000009 AN000010 AN000011
Analysis type MS MS MS MS MS MS MS MS
Chromatography type
Chromatography system
Column
MS Type ESI ESI ESI ESI ESI ESI ESI ESI
MS instrument type
MS instrument name
Ion Mode
Units pmol/ml pmol/ml nmol/ml nmol/ml pmol/ml pmol/ml pmol/ml umol/ml

Chromatography:

Chromatography ID:CH000004

MS:

MS ID:MS000004
Analysis ID:AN000004
MS Type:ESI
  
MS ID:MS000005
Analysis ID:AN000005
MS Type:ESI
  
MS ID:MS000006
Analysis ID:AN000006
MS Type:ESI
  
MS ID:MS000007
Analysis ID:AN000007
MS Type:ESI
  
MS ID:MS000008
Analysis ID:AN000008
MS Type:ESI
  
MS ID:MS000009
Analysis ID:AN000009
MS Type:ESI
  
MS ID:MS000010
Analysis ID:AN000010
MS Type:ESI
  
MS ID:MS000011
Analysis ID:AN000011
MS Type:ESI
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