Summary of Study ST000523
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000386. The data can be accessed directly via it's Project DOI: 10.21228/M8559K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000523 |
Study Title | Prenatal exposures and Metabolite and Lipid Profiles |
Study Summary | Our goal is to examine relationships between prenatal exposures (to metals, BPA, and phthalates) and metabolite and lipid profiles using untargeted approaches in mother-infant pairs from the Michigan Mother Infant Pairs (MMIP) cohort. Three plasma samples will be analyzed from each family: two maternal samples (from first trimester and time of admission for labor and delivery) and one child sample (from cord blood). We are interested in differences/correlations between family samples over time, and also the extent to which maternal exposures impact the lipidomes and metabolomes of both family members. |
Institute | University of Michigan |
Department | Biomedical Research Core Facilities |
Laboratory | Metabolomics core |
Last Name | Kachman |
First Name | Maureen |
Address | 6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714 |
mkachman@med.umich.edu | |
Phone | (734) 232-8175 |
Submit Date | 2016-12-16 |
Num Groups | 09-13-2016 |
Total Subjects | 168 |
Num Males | 168 |
Raw Data Available | Yes |
Raw Data File Type(s) | d, wiff |
Chear Study | Yes |
Analysis Type Detail | LC-MS |
Release Date | 2024-12-31 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
Project ID: | PR000386 |
Project DOI: | doi: 10.21228/M8559K |
Project Title: | Metabolome and lipidome of mother-infant cohort |
Project Summary: | A pilot analysis of the metabolome and lipidome of mother-infant pairs from Michigan using three samples (two maternal and one child) from each pair. Interested in prenatal environmental exposures and how they alter the metabolome and lipidome |
Institute: | University of Michigan |
Department: | Environmental Health Sciences |
Laboratory: | Padmanabhan Lab |
Last Name: | Padmanabhan |
First Name: | Vasantha |
Address: | Ann Arbor, MI |
Email: | vasantha@umich.edu |
Phone: | 734-647-0276 |
Subject:
Subject ID: | SU000545 |
Subject Type: | Animal |
Subject Species: | Homo sapiens |
Taxonomy ID: | 9606 |
Species Group: | Mammals |
Factors:
Subject type: Animal; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | Gender | Timing of Sample Collection | Type of Family Member |
---|---|---|---|---|
SA027289 | R000000098 | CHEAR_REFERENCE | CHEAR_REFERENCE | CHEAR_REFERENCE |
SA027290 | S00024101 | Female | 1st trimester | mother |
SA027291 | S00024100 | Female | 1st trimester | mother |
SA027292 | S00024102 | Female | 1st trimester | mother |
SA027293 | S00024103 | Female | 1st trimester | mother |
SA027294 | S00024099 | Female | 1st trimester | mother |
SA027295 | S00024104 | Female | 1st trimester | mother |
SA027296 | S00024097 | Female | 1st trimester | mother |
SA027297 | S00024094 | Female | 1st trimester | mother |
SA027298 | S00024093 | Female | 1st trimester | mother |
SA027299 | S00024095 | Female | 1st trimester | mother |
SA027300 | S00024096 | Female | 1st trimester | mother |
SA027301 | S00024105 | Female | 1st trimester | mother |
SA027302 | S00024098 | Female | 1st trimester | mother |
SA027303 | S00024107 | Female | 1st trimester | mother |
SA027304 | S00024116 | Female | 1st trimester | mother |
SA027305 | S00024115 | Female | 1st trimester | mother |
SA027306 | S00024117 | Female | 1st trimester | mother |
SA027307 | S00024118 | Female | 1st trimester | mother |
SA027308 | S00024063 | Female | 1st trimester | mother |
SA027309 | S00024114 | Female | 1st trimester | mother |
SA027310 | S00024113 | Female | 1st trimester | mother |
SA027311 | S00024108 | Female | 1st trimester | mother |
SA027312 | S00024092 | Female | 1st trimester | mother |
SA027313 | S00024109 | Female | 1st trimester | mother |
SA027314 | S00024110 | Female | 1st trimester | mother |
SA027315 | S00024111 | Female | 1st trimester | mother |
SA027316 | S00024106 | Female | 1st trimester | mother |
SA027317 | S00024112 | Female | 1st trimester | mother |
SA027318 | S00024064 | Female | 1st trimester | mother |
SA027319 | S00024071 | Female | 1st trimester | mother |
SA027320 | S00024073 | Female | 1st trimester | mother |
SA027321 | S00024074 | Female | 1st trimester | mother |
SA027322 | S00024076 | Female | 1st trimester | mother |
SA027323 | S00024075 | Female | 1st trimester | mother |
SA027324 | S00024070 | Female | 1st trimester | mother |
SA027325 | S00024069 | Female | 1st trimester | mother |
SA027326 | S00024065 | Female | 1st trimester | mother |
SA027327 | S00024091 | Female | 1st trimester | mother |
SA027328 | S00024066 | Female | 1st trimester | mother |
SA027329 | S00024067 | Female | 1st trimester | mother |
SA027330 | S00024068 | Female | 1st trimester | mother |
SA027331 | S00024077 | Female | 1st trimester | mother |
SA027332 | S00024072 | Female | 1st trimester | mother |
SA027333 | S00024087 | Female | 1st trimester | mother |
SA027334 | S00024085 | Female | 1st trimester | mother |
SA027335 | S00024088 | Female | 1st trimester | mother |
SA027336 | S00024089 | Female | 1st trimester | mother |
SA027337 | S00024090 | Female | 1st trimester | mother |
SA027338 | S00024078 | Female | 1st trimester | mother |
SA027339 | S00024084 | Female | 1st trimester | mother |
SA027340 | S00024086 | Female | 1st trimester | mother |
SA027341 | S00024083 | Female | 1st trimester | mother |
SA027342 | S00024079 | Female | 1st trimester | mother |
SA027343 | S00024081 | Female | 1st trimester | mother |
SA027344 | S00024080 | Female | 1st trimester | mother |
SA027345 | S00024082 | Female | 1st trimester | mother |
SA027346 | S00024185 | Female | term (birth) | child |
SA027347 | S00024184 | Female | term (birth) | child |
SA027348 | S00024186 | Female | term (birth) | child |
SA027349 | S00024193 | Female | term (birth) | child |
SA027350 | S00024196 | Female | term (birth) | child |
SA027351 | S00024195 | Female | term (birth) | child |
SA027352 | S00024191 | Female | term (birth) | child |
SA027353 | S00024177 | Female | term (birth) | child |
SA027354 | S00024178 | Female | term (birth) | child |
SA027355 | S00024197 | Female | term (birth) | child |
SA027356 | S00024180 | Female | term (birth) | child |
SA027357 | S00024181 | Female | term (birth) | child |
SA027358 | S00024182 | Female | term (birth) | child |
SA027359 | S00024183 | Female | term (birth) | child |
SA027360 | S00024217 | Female | term (birth) | child |
SA027361 | S00024223 | Female | term (birth) | child |
SA027362 | S00024222 | Female | term (birth) | child |
SA027363 | S00024224 | Female | term (birth) | child |
SA027364 | S00024226 | Female | term (birth) | child |
SA027365 | S00024228 | Female | term (birth) | child |
SA027366 | S00024199 | Female | term (birth) | child |
SA027367 | S00024216 | Female | term (birth) | child |
SA027368 | S00024227 | Female | term (birth) | child |
SA027369 | S00024204 | Female | term (birth) | child |
SA027370 | S00024215 | Female | term (birth) | child |
SA027371 | S00024205 | Female | term (birth) | child |
SA027372 | S00024201 | Female | term (birth) | child |
SA027373 | S00024210 | Female | term (birth) | child |
SA027374 | S00024206 | Female | term (birth) | child |
SA027375 | S00024167 | Female | term (birth) | mother |
SA027376 | S00024168 | Female | term (birth) | mother |
SA027377 | S00024166 | Female | term (birth) | mother |
SA027378 | S00024165 | Female | term (birth) | mother |
SA027379 | S00024169 | Female | term (birth) | mother |
SA027380 | S00024164 | Female | term (birth) | mother |
SA027381 | S00024173 | Female | term (birth) | mother |
SA027382 | S00024163 | Female | term (birth) | mother |
SA027383 | S00024174 | Female | term (birth) | mother |
SA027384 | S00024172 | Female | term (birth) | mother |
SA027385 | S00024171 | Female | term (birth) | mother |
SA027386 | S00024170 | Female | term (birth) | mother |
SA027387 | S00024150 | Female | term (birth) | mother |
SA027388 | S00024139 | Female | term (birth) | mother |
Collection:
Collection ID: | CO000539 |
Collection Summary: | None |
Sample Type: | Plasma |
Treatment:
Treatment ID: | TR000559 |
Treatment Summary: | None |
Sample Preparation:
Sampleprep ID: | SP000552 |
Sampleprep Summary: | None |
Sampleprep Protocol Filename: | EX00616-Sample_preparation_protocol.pdf |
Combined analysis:
Analysis ID | AN000798 | AN000799 | AN000800 | AN000801 |
---|---|---|---|---|
Analysis type | MS | MS | MS | MS |
Chromatography type | Reversed phase | Reversed phase | Reversed phase | Reversed phase |
Chromatography system | Agilent 1290 Infinity | Agilent 1290 Infinity | Agilent 1290 Infinity | Agilent 1290 Infinity |
Column | Waters Acquity HSS T3 | Waters Acquity HSS T3 | Waters Acquity HSS T3 | Waters Acquity HSS T3 |
MS Type | ESI | ESI | ESI | ESI |
MS instrument type | QTOF | QTOF | Triple TOF | Triple TOF |
MS instrument name | Agilent 6530 QTOF | Agilent 6530 QTOF | ABI Sciex 5600+ TripleTOF | ABI Sciex 5600+ TripleTOF |
Ion Mode | POSITIVE | NEGATIVE | POSITIVE | NEGATIVE |
Units | Peak area | Peak area | Peak area | Peak area |
Chromatography:
Chromatography ID: | CH000573 |
Methods Filename: | RP Pos Untargeted_2016_Agilent_460ulmin_2mm.m |
Chromatography Comments: | DQM0272 |
Instrument Name: | Agilent 1290 Infinity |
Column Name: | Waters Acquity HSS T3 |
Chromatography Type: | Reversed phase |
Chromatography ID: | CH000574 |
Methods Filename: | RP Neg Untargeted_2016_460ulmin_Agilent.m |
Chromatography Comments: | DQM0441 |
Instrument Name: | Agilent 1290 Infinity |
Column Name: | Waters Acquity HSS T3 |
Chromatography Type: | Reversed phase |
Chromatography ID: | CH000575 |
Methods Filename: | LIP_15min_MSMS_Jenny_new_20min_Positive.zip |
Chromatography Comments: | DQM0460 |
Instrument Name: | Agilent 1290 Infinity |
Column Name: | Waters Acquity HSS T3 |
Chromatography Type: | Reversed phase |
Chromatography ID: | CH000576 |
Methods Filename: | LIP_15min_MSMS_Jenny_New_20min_Negative.zip |
Chromatography Comments: | DQM0459 |
Instrument Name: | Agilent 1290 Infinity |
Column Name: | Waters Acquity HSS T3 |
Chromatography Type: | Reversed phase |
MS:
MS ID: | MS000705 |
Analysis ID: | AN000798 |
Instrument Name: | Agilent 6530 QTOF |
Instrument Type: | QTOF |
MS Type: | ESI |
Ion Mode: | POSITIVE |
Analysis Protocol File: | EX00616-Data_analysis.pdf |
MS ID: | MS000706 |
Analysis ID: | AN000799 |
Instrument Name: | Agilent 6530 QTOF |
Instrument Type: | QTOF |
MS Type: | ESI |
Ion Mode: | NEGATIVE |
Analysis Protocol File: | EX00616-Data_analysis.pdf |
MS ID: | MS000707 |
Analysis ID: | AN000800 |
Instrument Name: | ABI Sciex 5600+ TripleTOF |
Instrument Type: | Triple TOF |
MS Type: | ESI |
Ion Mode: | POSITIVE |
Analysis Protocol File: | EX00616-Data_analysis.pdf |
MS ID: | MS000708 |
Analysis ID: | AN000801 |
Instrument Name: | ABI Sciex 5600+ TripleTOF |
Instrument Type: | Triple TOF |
MS Type: | ESI |
Ion Mode: | NEGATIVE |
Analysis Protocol File: | EX00616-Data_analysis.pdf |