Summary of study ST000677

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000479. The data can be accessed directly via it's Project DOI: 10.21228/M84S5Z This work is supported by NIH grant, U2C- DK119886.

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Study IDST000677
Study TitleNonalcoholic steatohepatitis (NASH) changes with S.Q. Leptin administrations
Study TypeMS analysis
Study SummarySamples are from individuals with documented fatty liver disease (NAFLD) from whom serum was drawn at baseline and after 1 and 12 months of S.Q. Leptin administrations. The effect of leptin on degree of steatosis and inflammation was assessed in liver biopsies at baseline and following 1 year of treatment.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-05
Num Groups6
Total Subjects7
Raw Data AvailableYes
Raw Data File Type(s).wiff
Analysis Type DetailLC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M84S5Z
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:


Project:

Project ID:PR000479
Project DOI:doi: 10.21228/M84S5Z
Project Title:Nonalcoholic steatohepatitis (NASH) changes with S.Q. Leptin administrations
Project Type:MS analysis
Project Summary:Nonalcoholic steatohepatitis (NASH) Studies
Institute:University of Michigan
Department:Internal Medicine
Laboratory:Burant Lab
Last Name:Burant
First Name:Chuck
Address:1500 E. Medical Center Drive Ann Arbor, MI 48109
Email:burantc@umich.edu
Phone:734 615-3481

Subject:

Subject ID:SU000700
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Human

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id visit
SA038923S00025126closeout
SA038924S00025129closeout
SA038925S00025132closeout
SA038926S00025135closeout
SA038927S00025124initial visit
SA038928S00025121initial visit
SA038929S00025118intitial visit
SA038930S00025115intitial visit
SA038931S00025131month 1
SA038932S00025128month 1
SA038933S00025134month 1
SA038934S00025125month 1
SA038935S00025122month 1
SA038936S00025116month 1
SA038937S00025119month 1
SA038938S00025117month 12
SA038939S00025120month 12
SA038940S00025123month 12
SA038941S00025130visit 1
SA038942S00025127visit 1
SA038943S00025133visit 1
Showing results 1 to 21 of 21

Collection:

Collection ID:CO000694
Collection Summary:-
Sample Type:Blood

Treatment:

Treatment ID:TR000714
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000707
Sampleprep Summary:-
Sampleprep Protocol Filename:A004_-_Shotgun_Lipidomics.pdf

Combined analysis:

Analysis ID AN001040 AN001041
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Shimadzu CTO-20A Nexera X2 Shimadzu CTO-20A Nexera X2
Column Waters Acquity HSS T3 (50 x 2.1mm, 1.8um) Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
MS Type ESI ESI
MS instrument type Triple TOF Triple TOF
MS instrument name ABI Sciex 5600+ TripleTOF ABI Sciex 5600+ TripleTOF
Ion Mode NEGATIVE POSITIVE
Units peak area normalized peak area normalized

Chromatography:

Chromatography ID:CH000740
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
Chromatography Type:Reversed phase

MS:

MS ID:MS000935
Analysis ID:AN001040
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:NEGATIVE
  
MS ID:MS000936
Analysis ID:AN001041
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:POSITIVE
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