Summary of study ST000823

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000510. The data can be accessed directly via it's Project DOI: 10.21228/M8R68T This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000823
Study TitleMetabolic profiling of cyst fluid from patients with Intraductal Pancreatic Mucinous Neoplasm (part II)
Study TypeMS analysis
Study SummaryThe pancreatic cyst fluids were collected using a syringe aspiration of the cyst fluid immediately after surgical resection of the lesion. The cyst fluid were then aliquoted and stored in -80C freezer until ready to use. We plan on performing untargeted metabolomics analysis and unknown lipid analysis and identification on these pancreatic cyst fluid to find potential biomarkers that correlate with histopathological assessment and clinical behavior of these cystic lesions and thus to guide clinical management of patients. Abbreviations: IPMN - Intraductal Pancreatic Mucinous Neoplasm; MCN - mucinous cystic neoplasm; SCA - serous cystadenoma.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-07-14
Num Groups5
Total Subjects10
Raw Data AvailableYes
Raw Data File Type(s).d, .wiff
Analysis Type DetailLC-MS
Release Date2018-02-07
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8R68T
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:


Project:

Project ID:PR000510
Project DOI:doi: 10.21228/M8R68T
Project Title:Metabolic profiling of cyst fluid from patients with Intraductal Pancreatic Mucinous Neoplasm
Project Type:MS analysis
Project Summary:Identify novel cystic fluid biomarkers to guide clinical management of patients with intraductal pancreatic mucinous neoplasm (IPMN) by metabolic profiling of the cyst fluid.
Institute:University of Michigan
Department:Pathology
Laboratory:Shi Lab
Last Name:Shi
First Name:Jiaqi
Address:Ann Arbor, MI
Email:jiaqis@umich.edu
Phone:734-647-3967

Subject:

Subject ID:SU000849
Subject Type:HUMAN
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Human

Factors:

Subject type: HUMAN; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Diagnosis Dysplasia
SA045845S00027604IPMN LGD
SA045846S00027600IPMN LGD
SA045847S00027601IPMN LGD
SA045848S00027597IPMN LGD
SA045849S00027602MCN LGD
SA045850S00027603MCN LGD
SA045851S00027596MCN LGD
SA045852S00027605SCA N/A
SA045853S00027598SCA N/A
SA045854S00027599SCA N/A
Showing results 1 to 10 of 10

Collection:

Collection ID:CO000843
Collection Summary:-
Sample Type:Cyst fluid

Treatment:

Treatment ID:TR000863
Treatment Summary:-

Sample Preparation:

Sampleprep ID:SP000856
Sampleprep Summary:-
Sampleprep Protocol Filename:A003_-_Untargeted_Metabolomics.pdf

Combined analysis:

Analysis ID AN001306 AN001307 AN001308 AN001309
Analysis type MS MS MS MS
Chromatography type Reversed phase Reversed phase Reversed phase Reversed phase
Chromatography system Agilent Agilent Shimadzu CTO-20A Nexera X2 Shimadzu CTO-20A Nexera X2
Column Waters Acquity HSS T3 (50 x 2.1mm, 1.8um) Waters Acquity HSS T3 (50 x 2.1mm, 1.8um) Waters Acquity HSS T3 (50 x 2.1mm, 1.8um) Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
MS Type ESI ESI ESI ESI
MS instrument type QTOF QTOF Triple TOF Triple TOF
MS instrument name Agilent 6530 QTOF Agilent 6530 QTOF ABI Sciex 5600+ TripleTOF ABI Sciex 5600+ TripleTOF
Ion Mode NEGATIVE POSITIVE NEGATIVE POSITIVE
Units peak area peak area peak area peak area

Chromatography:

Chromatography ID:CH000915
Instrument Name:Agilent
Column Name:Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
Chromatography Type:Reversed phase
  
Chromatography ID:CH000916
Instrument Name:Shimadzu CTO-20A Nexera X2
Column Name:Waters Acquity HSS T3 (50 x 2.1mm, 1.8um)
Chromatography Type:Reversed phase

MS:

MS ID:MS001199
Analysis ID:AN001306
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
  
MS ID:MS001200
Analysis ID:AN001307
Instrument Name:Agilent 6530 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:POSITIVE
  
MS ID:MS001201
Analysis ID:AN001308
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:NEGATIVE
  
MS ID:MS001202
Analysis ID:AN001309
Instrument Name:ABI Sciex 5600+ TripleTOF
Instrument Type:Triple TOF
MS Type:ESI
Ion Mode:POSITIVE
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